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The map label for this gene is gudP [H]

Identifier: 152969383

GI number: 152969383

Start: 920411

End: 921742

Strand: Direct

Name: gudP [H]

Synonym: KPN_00826

Alternate gene names: 152969383

Gene position: 920411-921742 (Clockwise)

Preceding gene: 152969376

Following gene: 152969384

Centisome position: 17.32

GC content: 50.98

Gene sequence:

>1332_bases
ATGTCACGTATAGATACGCTGGTCTGTACTGACGCCAGGAAAACGAAATATCGTTTCGTGGTTTTGACGATGATTTTTCT
GGTGTATGCCATCAATTACGCCGACCGAACGAATATTGGCGCGGTACTGCCTTTCATCATTGATGAGTTTCATATCAATA
ATTTTGAAGCCGGGGCCATCGCCAGTATGTTTTTCCTCGGCTATGCGGTAAGCCAGATCCCGGCCGGCTTTTTCATCGCC
AAACGCGGTACCCGGGGGCTGGTATCGCTCTCCATTTTCGGCTTCTCCGCCTTTACCTGGCTGATGGGCACGGTGAGCTC
CGTGTTTGGCCTGAAGCTGGTGCGGCTGGGACTGGGGCTGAGCGAAGGGCCTTGCCCGGTGGGGCTGGCTTCCACCATAA
ATAACTGGTTTCCACCAAAGGAGAAAGCCACGGCAACCGGCGTTTACATCGCGGCGACCATGTTTGCGCCGATTATTGTG
CCGCCGCTGGCGGTGTGGATTGCGGTGACCTGGGGCTGGCGGTGGGTCTTTTTCTCCTTCGCGATACCCGGAATTGTGGC
GGCCATCGCGTGGTATCTGCTGGTCAAATCCAAGCCTGCTGAGAGCGGATTTGTTTCCCAAAGCGAACTGGCAGAGATTA
ATGCCGGGCGTGAAAGTCATAATAATAGCGTACGCGAAAATATCTTAATTGCCGAAAGATTCACCTGGCTGGATAAAATC
ATTCGGGTAAAGAAAATGGCGCCAATTGATACGGCGAAAGGCTTATTCACCTCAAAAAATATTCTCGGTGACTGCCTGGC
ATATTTTATGATGGTTAGCGTGCTGTACGGATTATTAACCTGGATCCCCCTGTATTTAGTCAAAGAGCGCGGTTTCGATG
TAATGAGTATGGGCTTCGTGGCCAGTATGCCGTGCATCGGCGGCTTTATTGGCGCGATCGGCGGCGGATGGGTTTCGGAT
AAGCTATTAGGCCGCCGGCGTAAACCCACCATGATGTTCACTGCGGTGTCAACGGTGGTCATGATGCTAATTATGCTGAA
TATCCCGGCCAGCACCCTGGCAGTTTGTATTGGATTATTCTTTGTCGGCTTTTGTTTAAATATCGGCTGGCCAGCCTTTA
CCGCGTACGGTATGGCCGTTTCGGATAGCAAAACCTATCCAATCGCCTCTTCCATAATTAATAGCGGCGGCAACCTCGGT
GGATTTGTGGCGCCGATGGCGGCTGGTTTCTTGCTTGATAAAACCGGGAGTTTTAATTCTGTATTTACCTATTTTGGTAT
CTGCGCCGCCATTGGTTTGGTGGTGATTCTTTTCCTCGATGAACCACAATAA

Upstream 100 bases:

>100_bases
GAAAAGCATTTATCTCTTGCTCCTGTATGGATAGTAAAACGCGGTGATCCGAAGCGGCAGCTTACAGCGAAGTGGATGAG
GTATAAAACGAGGAAACCCT

Downstream 100 bases:

>100_bases
CGGAAATATATCCTGTTAATTAATATGACGTAATGTCATGGAGTGAAACTATGTTATTGAAAGATAAAGTCGCCATTATT
ACTGGCGCGGCCTCCGCACG

Product: putative general substrate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIA
KRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIV
PPLAVWIAVTWGWRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIAERFTWLDKI
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWVSD
KLLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLG
GFVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ

Sequences:

>Translated_443_residues
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIA
KRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIV
PPLAVWIAVTWGWRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIAERFTWLDKI
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWVSD
KLLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLG
GFVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ
>Mature_442_residues
SRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIAK
RGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVP
PLAVWIAVTWGWRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIAERFTWLDKII
RVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWVSDK
LLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGG
FVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=289, Percent_Identity=25.2595155709343, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI9945322, Length=418, Percent_Identity=23.6842105263158, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI148743791, Length=385, Percent_Identity=21.038961038961, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI9966811, Length=422, Percent_Identity=23.4597156398104, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21322234, Length=423, Percent_Identity=23.1678486997636, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=28.476821192053, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789515, Length=456, Percent_Identity=28.0701754385965, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=27.2311212814645, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=27.7027027027027, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI2367193, Length=308, Percent_Identity=24.025974025974, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082310, Length=369, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=340, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=333, Percent_Identity=24.9249249249249, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=326, Percent_Identity=25.1533742331288, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=392, Percent_Identity=23.9795918367347, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=411, Percent_Identity=24.0875912408759, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=411, Percent_Identity=24.0875912408759, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=443, Percent_Identity=22.5733634311512, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=297, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=278, Percent_Identity=24.1007194244604, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=215, Percent_Identity=25.1162790697674, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639764, Length=454, Percent_Identity=25.1101321585903, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654215, Length=458, Percent_Identity=23.1441048034935, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19922400, Length=445, Percent_Identity=23.3707865168539, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641682, Length=406, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648416, Length=452, Percent_Identity=22.1238938053097, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356189, Length=452, Percent_Identity=22.1238938053097, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573708, Length=443, Percent_Identity=20.9932279909707, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573707, Length=443, Percent_Identity=20.9932279909707, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20130167, Length=459, Percent_Identity=23.7472766884532, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655271, Length=421, Percent_Identity=21.6152019002375, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130135, Length=421, Percent_Identity=21.6152019002375, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584153, Length=282, Percent_Identity=22.6950354609929, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45550460, Length=321, Percent_Identity=22.7414330218069, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653727, Length=274, Percent_Identity=24.0875912408759, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48155; Mature: 48023

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAI
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
ASMFFLGYAVSQIPAGFFIAKRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGL
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVPPLAVWIAVTWGWRWVFFSF
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIAERFTWLDKI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHH
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFV
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ASMPCIGGFIGAIGGGWVSDKLLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLF
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGGFVAPMAAGFLLDKTGSFNS
HHHHHHHCCCHHHHHHCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH
VFTYFGICAAIGLVVILFLDEPQ
HHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
SRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAI
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
ASMFFLGYAVSQIPAGFFIAKRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGL
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVPPLAVWIAVTWGWRWVFFSF
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIAERFTWLDKI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHH
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFV
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ASMPCIGGFIGAIGGGWVSDKLLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLF
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGGFVAPMAAGFLLDKTGSFNS
HHHHHHHCCCHHHHHHCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH
VFTYFGICAAIGLVVILFLDEPQ
HHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]