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The map label for this gene is alr

Identifier: 151222187

GI number: 151222187

Start: 2193212

End: 2194360

Strand: Reverse

Name: alr

Synonym: NWMN_1975

Alternate gene names: 151222187

Gene position: 2194360-2193212 (Counterclockwise)

Preceding gene: 151222188

Following gene: 151222186

Centisome position: 76.22

GC content: 36.12

Gene sequence:

>1149_bases
ATGTCGGATAAATATTATAGATCTGCGTATATGAATGTAGATTTAAACGCTGTTGCATCAAATTTCAAAGTATTCAGTAC
ATTGCATCCAAATAAAACAGTGATGGCTGTCGTTAAAGCCAATGCCTATGGACTAGGTAGTGTTAAAGTAGCACGTCATT
TAATGGAAAATGGCGCCACATTTTTTGCTGTAGCAACGTTAGATGAAGCGATAGAACTTAGAATGCATGGGATTACTGCT
AAAATTTTAGTCTTAGGTGTGTTACCAGCTAAAGATATTGATAAAGCGATACAACACCGAGTTGCCTTAACGGTTCCGTC
TAAACAGTGGTTGAAAGAAGCAATTAAAAACATTTCTGGTGAGCAAGAGAAAAAGTTATGGTTGCACATTAAATTAGATA
CAGGAATGGGACGTTTAGGTATTAAAGATACTAAAACGTATCAAGAAGTGATTGAAATCATTCAACAATATGAGCAACTT
GTATTTGAAGGCGTGTTTACACACTTTGCCTGTGCTGACGAACCAGGAGATATGACAACTGAACAATATCAACGTTTTAA
AGATATGGTCAATGAAGCAATTAAACCTGAATATATACATTGTCAGAACTCAGCAGGCTCTCTATTAATGGATTGCCAAT
TCTGTAATGCAATAAGACCAGGAATTTCCCTTTATGGATATTATCCATCAGAGTATGTACAGCAAAAAGTTAAAGTACAC
CTTAAACCAAGTGTGCAATTAATTGCTAATGTAGTTCAAACAAAGACGCTACAAGCGGGTGAGTCTGTAAGTTATGGTGC
AACTTATACAGCTACTGACCCAACTACAATAGCATTGTTACCTATTGGATATGCAGATGGCTATTTACGCATAATGCAAG
GTAGCTTTGTAAATGTAAATGGTCATCAATGCGAAGTTATTGGTCGCGTATGTATGGATCAGACAATTGTTAAAGTGCCA
GATCAAGTTAAAGCTGGAGATTCGGTGATTTTAATAGATAATCATAGAGAAAGTCCACAGTCGGTAGAGGTGGTAGCTGA
AAAGCAACATACTATTAATTATGAAGTGCTTTGTAACTTGTCGAGACGTTTGCCGCGAATCTATCATGATGGTGATCAAC
GTTTTGTAACAAATGAATTGTTAAAATAA

Upstream 100 bases:

>100_bases
TGAGCCAAGTTGTTTTAGAAAAGTCAGCATTTTAAATTTGTTATACAATGATAATTAAGATCTAGTTTTAAAACGTGTGG
GAATTACAGGAGGAAGTAAT

Downstream 100 bases:

>100_bases
TATGGTCAGTGCATATAAAATTTGTTATCATTAGAGTAATTAAAGGTCATTTAATAACTTTTGGAATCAATTGGAGGTTC
TCATATGTTATCTTTTAGTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQL
VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Sequences:

>Translated_382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQL
VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
>Mature_381_residues
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAK
ILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLV
FEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHL
KPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPD
QVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=370, Percent_Identity=32.7027027027027, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=32.2493224932249, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR1_STAA8 (Q9ZAH5)

Other databases:

- EMBL:   Y16431
- EMBL:   CP000253
- RefSeq:   YP_500784.1
- ProteinModelPortal:   Q9ZAH5
- SMR:   Q9ZAH5
- STRING:   Q9ZAH5
- EnsemblBacteria:   EBSTAT00000030513
- GeneID:   3920930
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_02305
- eggNOG:   COG0787
- GeneTree:   EBGT00050000023673
- HOGENOM:   HBG712172
- OMA:   WGKQVLA
- ProtClustDB:   CLSK885747
- BioCyc:   SAUR93061:SAOUHSC_02305-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 42824; Mature: 42693

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 39-39 ACT_SITE 265-265

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISG
EEEEEEHHHHHHHHHCCCEEEEHEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNL
CCCHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHEECH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC
>Mature Secondary Structure 
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISG
EEEEEEHHHHHHHHHCCCEEEEHEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNL
CCCHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHEECH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9756984