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The map label for this gene is pheA [H]

Identifier: 150398614

GI number: 150398614

Start: 3633467

End: 3634321

Strand: Direct

Name: pheA [H]

Synonym: Smed_3428

Alternate gene names: 150398614

Gene position: 3633467-3634321 (Clockwise)

Preceding gene: 150398613

Following gene: 150398615

Centisome position: 96.08

GC content: 61.52

Gene sequence:

>855_bases
GTGACAGCCAAGACCAACCGGATTTCCTTTCAGGGCGACTACGGCGCCAATTCCGACATGGCCTGCCGCGACATGTTCCC
GGCGATGGAGCCGCTGCCCTGCCAAACCTTCGAAGATGCCTTCCTGGCGGTGGAAAACGGCGAGGCCGATCTCGCGATGA
TCCCGATCGAGAACACGATCGCCGGTCGAGTCGCCGACATTCACCACCTCCTGCCGGAATCGCGCCTTAACATCGTCGGC
GAATATTTCATGCCGATTCGCTTCCAGCTGATGGTGCTGCCCGGCGTCAAACGCGACGAGATACGTACGGTTCACAGCCA
TATCCACGCGCTCGGACAATGCCGCAAGATCGTGCGTGCCAATGGCTGGAAGCCGGTGGTCGCGGGCGATACGGCCGGCG
CCGCCAAGCTCGTCAGGGAAGTCGGAGACCGCTCCATGGCGGCGCTTGCTCCGCGCCTTGCCGCCGATCTCTACGGACTC
GAAATCATCGCCGAGAACGTGGAAGACACCGACAGCAACGTCACGCGCTTCGTCGTGCTGTCGCGGGAAGAGAAACGGGC
GGCGCGCACGTCAAAGGACGAGCTGATCATCACGACCTTTGTCTTCAACGTGCGCAATATCCCGGCGGCGCTCTACAAGG
CCATGGGCGGTTTCGCGACGAACGGCATCAACATGACCAAGCTCGAGAGCTATCAGCTCGGCGGCAGGTTCGTGGCGACC
CAGTTCTATGCGGATATCGAAGGTCACCCCGACGATATCGGCGTGCGCCACGCGATGGACGAGTTGCGCTTCTTCTCCGA
AAACGTACGCATTCTCGGCACTTATCCGGCGCATCCGATGCGCGGTGTGCTCTGA

Upstream 100 bases:

>100_bases
GATTCGGTGCCGCTCGGCGTCGACACGCCTGCAGATCTCGACAAGGCCCGCCGGATCCTTTCGGCCCGGGCCTGAGATTT
TCACATCAAGGGGAACTGAC

Downstream 100 bases:

>100_bases
AGATCGGCGCCGATGACGAAGGCGGTCTTGGGTCAGTGGCGCGCGAGATCATTTGAACCGCGCCGGAGCCACTGCGATTG
ATCGTGGCTCCCCAACTCCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTAKTNRISFQGDYGANSDMACRDMFPAMEPLPCQTFEDAFLAVENGEADLAMIPIENTIAGRVADIHHLLPESRLNIVG
EYFMPIRFQLMVLPGVKRDEIRTVHSHIHALGQCRKIVRANGWKPVVAGDTAGAAKLVREVGDRSMAALAPRLAADLYGL
EIIAENVEDTDSNVTRFVVLSREEKRAARTSKDELIITTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGRFVAT
QFYADIEGHPDDIGVRHAMDELRFFSENVRILGTYPAHPMRGVL

Sequences:

>Translated_284_residues
MTAKTNRISFQGDYGANSDMACRDMFPAMEPLPCQTFEDAFLAVENGEADLAMIPIENTIAGRVADIHHLLPESRLNIVG
EYFMPIRFQLMVLPGVKRDEIRTVHSHIHALGQCRKIVRANGWKPVVAGDTAGAAKLVREVGDRSMAALAPRLAADLYGL
EIIAENVEDTDSNVTRFVVLSREEKRAARTSKDELIITTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGRFVAT
QFYADIEGHPDDIGVRHAMDELRFFSENVRILGTYPAHPMRGVL
>Mature_283_residues
TAKTNRISFQGDYGANSDMACRDMFPAMEPLPCQTFEDAFLAVENGEADLAMIPIENTIAGRVADIHHLLPESRLNIVGE
YFMPIRFQLMVLPGVKRDEIRTVHSHIHALGQCRKIVRANGWKPVVAGDTAGAAKLVREVGDRSMAALAPRLAADLYGLE
IIAENVEDTDSNVTRFVVLSREEKRAARTSKDELIITTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGRFVATQ
FYADIEGHPDDIGVRHAMDELRFFSENVRILGTYPAHPMRGVL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=32.2463768115942, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31484; Mature: 31352

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTNRISFQGDYGANSDMACRDMFPAMEPLPCQTFEDAFLAVENGEADLAMIPIENTI
CCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCHH
AGRVADIHHLLPESRLNIVGEYFMPIRFQLMVLPGVKRDEIRTVHSHIHALGQCRKIVRA
HHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPVVAGDTAGAAKLVREVGDRSMAALAPRLAADLYGLEIIAENVEDTDSNVTRFVVL
CCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
SREEKRAARTSKDELIITTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGRFVAT
ECHHHHHHCCCCCCEEEEEEEHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPDDIGVRHAMDELRFFSENVRILGTYPAHPMRGVL
EEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TAKTNRISFQGDYGANSDMACRDMFPAMEPLPCQTFEDAFLAVENGEADLAMIPIENTI
CCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCHH
AGRVADIHHLLPESRLNIVGEYFMPIRFQLMVLPGVKRDEIRTVHSHIHALGQCRKIVRA
HHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPVVAGDTAGAAKLVREVGDRSMAALAPRLAADLYGLEIIAENVEDTDSNVTRFVVL
CCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
SREEKRAARTSKDELIITTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGRFVAT
ECHHHHHHCCCCCCEEEEEEEHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPDDIGVRHAMDELRFFSENVRILGTYPAHPMRGVL
EEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]