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The map label for this gene is cdd [H]

Identifier: 150398529

GI number: 150398529

Start: 3540825

End: 3541283

Strand: Direct

Name: cdd [H]

Synonym: Smed_3340

Alternate gene names: 150398529

Gene position: 3540825-3541283 (Clockwise)

Preceding gene: 150398528

Following gene: 150398530

Centisome position: 93.63

GC content: 63.18

Gene sequence:

>459_bases
ATGTCGCCCGGAAGTGTGCAGCGGTTCCGGGATGACGACATGCACAACAATAAGGAATGCCCCATGTCGAAGGACGAACT
CTTTGTCGCGGCGCGCGAAGCCATGGCAAAGGCGCATGCGCCCTATTCGAAGTTTCCGGTCGGCGCCGCCATTCGCGCCG
AGGACGGCAAGATCTATACGGGCGCGAACATCGAGAACCTGTCCTTTCCGGAAGGCTGGTGCGCCGAGACCACCGCGATC
AGCCACATGGTGATGGCCGGCCAGCGCAAGATCACGGAAGTGGCAGTGGTTGCCGAGAAGCTCGCGCTCTGCCCGCCCTG
CGGCGGCTGCCGCCAGCGCCTGGCGGAATTTTCCGGCGCCAGCACCCGCATCTATCTCTGTGACGAGACGGGGATCAGGA
AGACGCTGGCGCTCTCCGATCTTCTGCCGCACAGCTTCGAGACGGAGATCCTCGGATGA

Upstream 100 bases:

>100_bases
ACTGCCCTATATCCTCACCGTCGTTCTGCTTGCCGGATTTATCGGCAAGGCCATTCCGCCCAAGGCGGGCGGCGTACCCT
ATGTGAAGGAGCGCTAATGC

Downstream 100 bases:

>100_bases
CGGCGGCGGCAGAGTTCCTCAAGGGTAAACTCGGAGCGCTTGCGCCCCGCTACGCAATCGTGCTCGGTTCCGGTCTCGGT
GCGCTCGTCGACGCAGTGGC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSPGSVQRFRDDDMHNNKECPMSKDELFVAAREAMAKAHAPYSKFPVGAAIRAEDGKIYTGANIENLSFPEGWCAETTAI
SHMVMAGQRKITEVAVVAEKLALCPPCGGCRQRLAEFSGASTRIYLCDETGIRKTLALSDLLPHSFETEILG

Sequences:

>Translated_152_residues
MSPGSVQRFRDDDMHNNKECPMSKDELFVAAREAMAKAHAPYSKFPVGAAIRAEDGKIYTGANIENLSFPEGWCAETTAI
SHMVMAGQRKITEVAVVAEKLALCPPCGGCRQRLAEFSGASTRIYLCDETGIRKTLALSDLLPHSFETEILG
>Mature_151_residues
SPGSVQRFRDDDMHNNKECPMSKDELFVAAREAMAKAHAPYSKFPVGAAIRAEDGKIYTGANIENLSFPEGWCAETTAIS
HMVMAGQRKITEVAVVAEKLALCPPCGGCRQRLAEFSGASTRIYLCDETGIRKTLALSDLLPHSFETEILG

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=132, Percent_Identity=38.6363636363636, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540514, Length=130, Percent_Identity=43.0769230769231, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551074, Length=119, Percent_Identity=40.3361344537815, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=120, Percent_Identity=36.6666666666667, Blast_Score=77, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920920, Length=142, Percent_Identity=42.2535211267606, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24582741, Length=143, Percent_Identity=39.8601398601399, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582744, Length=147, Percent_Identity=41.4965986394558, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 16566; Mature: 16435

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPGSVQRFRDDDMHNNKECPMSKDELFVAAREAMAKAHAPYSKFPVGAAIRAEDGKIYT
CCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEE
GANIENLSFPEGWCAETTAISHMVMAGQRKITEVAVVAEKLALCPPCGGCRQRLAEFSGA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
STRIYLCDETGIRKTLALSDLLPHSFETEILG
CEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SPGSVQRFRDDDMHNNKECPMSKDELFVAAREAMAKAHAPYSKFPVGAAIRAEDGKIYT
CCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEE
GANIENLSFPEGWCAETTAISHMVMAGQRKITEVAVVAEKLALCPPCGGCRQRLAEFSGA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
STRIYLCDETGIRKTLALSDLLPHSFETEILG
CEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]