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The map label for this gene is yjjN [H]

Identifier: 150398422

GI number: 150398422

Start: 3406291

End: 3407307

Strand: Direct

Name: yjjN [H]

Synonym: Smed_3230

Alternate gene names: 150398422

Gene position: 3406291-3407307 (Clockwise)

Preceding gene: 150398421

Following gene: 150398425

Centisome position: 90.07

GC content: 65.09

Gene sequence:

>1017_bases
GTGAAAGCCGTCCTATGTTCAGAGCCGGGCCACATCGCCCTTGTCGCCCGCGATGCGCCTGAGGCACCGCCGCCCGGCTC
GGTGCGCCTTGCCGTCAGCCGCGTCGGCATCTGCGGCACCGATTATCATATCTTCGAGGGCAAGCACCCCTTTCTCGAAT
ATCCGCGCGTGATGGGCCACGAAATCTCGGCGAGAGTGATCGAGGGCGGTCCCGGCACCCGGCTCACGCCGGGAACGCTC
GTCGTCGTCAACCCCTATCTCTCCTGCGGAACTTGCAGCGCCTGCCGCAAAGGCAAGCCGAACTGCTGCACGGCGATCCG
CGTTCTCGGCGTCCACACCGACGGCGCGTTCTGTGAAGAAATAGTCATGCCCGAACAGAACCTTTATCCGGCTGATGGCC
TGTCGCCCGAAGCCGCCGCCGCCGTCGAGTTCCTGGCCATCGGCGCGCACGCCGTCCGGCGTTCGGCGGTAGGCAAAGAC
GTCCGTTCGCTGGTGATCGGTGCCGGGCCGATCGGACTTGGTACGGCCGTCTTTTCCCGGATCGCCGGTCATGACGTCAG
GCTGCTCGACACGAGCGTGGAGCGACTGGCCTTCGCCGCCGAAAAGCTCGGCTTCTCCCCTGGCATCCTCGCGGGTGACG
ATGCGGCGCTTGCGCAGGCAACCGGCGGGGATGGTTTCGACGTCGTCTTCGACGCCACCGGCAGCGCCCGGTCCATGGAA
CGGGCATTTGCCCACGTCGCCCATGGCGGAACGCTGGTCTTCGTCAGCGTGGTCAAGGAAGAGATCCGCTTCTCGGATCC
CGAATTCCACAAGCGGGAAATGACGCTTGTCGCAAGCCGCAACGCCACGCGCGAGGATTTCGATCACGTCATTCAGTCGC
TTTCGGCGGGGCTCGTTCCGATCGAGGCGCTCGTCACACACCGCACAACGCTTGAGGACCTCGCCCATGACCTTCCGCGC
TGGGCCCATGATAAGACGGGGCTCGTCAAGGCAGTAGTCGCGGTAAGCGCCTGCTAG

Upstream 100 bases:

>100_bases
CTGATCATCGTCATCGTCTATTTCGACCAGTTGCGGCGGCGGGGCGCGCGATGATGGCCGCCCGCCCGCACCCGGCCGCA
AGCAAACTTCGGAGCACCAC

Downstream 100 bases:

>100_bases
CCAGGCCGTCGCCATCGGCACCTGCTTGCCGCCGCATGCAGGGCGTCGATTTTGTCCGGCCATAGATCGAAGGGTAAAGG
TATAGACTTAACTTTCCGGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKAVLCSEPGHIALVARDAPEAPPPGSVRLAVSRVGICGTDYHIFEGKHPFLEYPRVMGHEISARVIEGGPGTRLTPGTL
VVVNPYLSCGTCSACRKGKPNCCTAIRVLGVHTDGAFCEEIVMPEQNLYPADGLSPEAAAAVEFLAIGAHAVRRSAVGKD
VRSLVIGAGPIGLGTAVFSRIAGHDVRLLDTSVERLAFAAEKLGFSPGILAGDDAALAQATGGDGFDVVFDATGSARSME
RAFAHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHVIQSLSAGLVPIEALVTHRTTLEDLAHDLPR
WAHDKTGLVKAVVAVSAC

Sequences:

>Translated_338_residues
MKAVLCSEPGHIALVARDAPEAPPPGSVRLAVSRVGICGTDYHIFEGKHPFLEYPRVMGHEISARVIEGGPGTRLTPGTL
VVVNPYLSCGTCSACRKGKPNCCTAIRVLGVHTDGAFCEEIVMPEQNLYPADGLSPEAAAAVEFLAIGAHAVRRSAVGKD
VRSLVIGAGPIGLGTAVFSRIAGHDVRLLDTSVERLAFAAEKLGFSPGILAGDDAALAQATGGDGFDVVFDATGSARSME
RAFAHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHVIQSLSAGLVPIEALVTHRTTLEDLAHDLPR
WAHDKTGLVKAVVAVSAC
>Mature_338_residues
MKAVLCSEPGHIALVARDAPEAPPPGSVRLAVSRVGICGTDYHIFEGKHPFLEYPRVMGHEISARVIEGGPGTRLTPGTL
VVVNPYLSCGTCSACRKGKPNCCTAIRVLGVHTDGAFCEEIVMPEQNLYPADGLSPEAAAAVEFLAIGAHAVRRSAVGKD
VRSLVIGAGPIGLGTAVFSRIAGHDVRLLDTSVERLAFAAEKLGFSPGILAGDDAALAQATGGDGFDVVFDATGSARSME
RAFAHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHVIQSLSAGLVPIEALVTHRTTLEDLAHDLPR
WAHDKTGLVKAVVAVSAC

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=318, Percent_Identity=29.559748427673, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501939, Length=349, Percent_Identity=24.0687679083095, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI156523966, Length=349, Percent_Identity=24.0687679083095, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI226510992, Length=338, Percent_Identity=41.4201183431953, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1787863, Length=352, Percent_Identity=31.5340909090909, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1788073, Length=349, Percent_Identity=28.6532951289398, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788407, Length=335, Percent_Identity=26.5671641791045, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790045, Length=297, Percent_Identity=26.2626262626263, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790718, Length=312, Percent_Identity=28.525641025641, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082125, Length=352, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786825, Length=368, Percent_Identity=23.0978260869565, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788075, Length=309, Percent_Identity=23.3009708737864, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=323, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562878, Length=185, Percent_Identity=32.4324324324324, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=329, Percent_Identity=29.1793313069909, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319257, Length=336, Percent_Identity=32.1428571428571, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319955, Length=329, Percent_Identity=29.1793313069909, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=25.6484149855908, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=332, Percent_Identity=28.0120481927711, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137530, Length=324, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737897, Length=323, Percent_Identity=26.9349845201238, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35615; Mature: 35615

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLCSEPGHIALVARDAPEAPPPGSVRLAVSRVGICGTDYHIFEGKHPFLEYPRVMGH
CCCEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHCHHHHCC
EISARVIEGGPGTRLTPGTLVVVNPYLSCGTCSACRKGKPNCCTAIRVLGVHTDGAFCEE
CCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCHHHHH
IVMPEQNLYPADGLSPEAAAAVEFLAIGAHAVRRSAVGKDVRSLVIGAGPIGLGTAVFSR
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHH
IAGHDVRLLDTSVERLAFAAEKLGFSPGILAGDDAALAQATGGDGFDVVFDATGSARSME
HCCCCEEEHHHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCEEEEEECCCCHHHHH
RAFAHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHVIQSLSAGLVP
HHHHHHHCCCEEEHHHHHHHHHCCCCCCHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCH
IEALVTHRTTLEDLAHDLPRWAHDKTGLVKAVVAVSAC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAVLCSEPGHIALVARDAPEAPPPGSVRLAVSRVGICGTDYHIFEGKHPFLEYPRVMGH
CCCEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHCHHHHCC
EISARVIEGGPGTRLTPGTLVVVNPYLSCGTCSACRKGKPNCCTAIRVLGVHTDGAFCEE
CCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCHHHHH
IVMPEQNLYPADGLSPEAAAAVEFLAIGAHAVRRSAVGKDVRSLVIGAGPIGLGTAVFSR
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHH
IAGHDVRLLDTSVERLAFAAEKLGFSPGILAGDDAALAQATGGDGFDVVFDATGSARSME
HCCCCEEEHHHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCEEEEEECCCCHHHHH
RAFAHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHVIQSLSAGLVP
HHHHHHHCCCEEEHHHHHHHHHCCCCCCHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCH
IEALVTHRTTLEDLAHDLPRWAHDKTGLVKAVVAVSAC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]