| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
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The map label for this gene is gyrB [H]
Identifier: 150398412
GI number: 150398412
Start: 3393136
End: 3395571
Strand: Direct
Name: gyrB [H]
Synonym: Smed_3220
Alternate gene names: 150398412
Gene position: 3393136-3395571 (Clockwise)
Preceding gene: 150398411
Following gene: 150398414
Centisome position: 89.72
GC content: 63.01
Gene sequence:
>2436_bases ATGACCGAAATTTCTGAGACCGAAGCCGGCGCAATCGCCGAATATGGTGCCGATTCCATCAAGGTGCTGAAAGGCCTCGA TGCCGTACGCAAGCGCCCGGGCATGTATATCGGCGACACCGACGACGGCTCAGGTTTGCACCACATGGTCTACGAAGTCG TGGACAACGCGATCGACGAGGCTTTGGCAGGGCACGCGGATCTGGTTACGGTGACGCTCAACCCCGACGGCTCCGTAACC GTGACCGACAACGGCCGCGGTATACCGACCGACATTCACAGGGAAGAGGGCGTCTCGGCGGCGGAAGTCATCATGACGCA GCTTCATGCCGGCGGGAAATTCGACCAGAATTCCTACAAGGTCTCCGGCGGTCTGCACGGCGTCGGCGTTTCGGTCGTCA ACGCCCTTTCCGTGTCGCTGAAGCTCAAGATTCGCCGTTCGGGCAAGATCCACGAAATGAGCTTCACCCACGGCGTTGCC GACGGGCCGCTCAAAGTGACGGGCGACGCCGGCAGCGACACCGGGACGGAGGTGACCTTCACGCCGAGCGAACAGACCTT TTCGAACATCGAATTCGAGTTCGCCAGGCTCGAGCATCGCCTGCGCGAACTCGCCTTCCTGAATTCCGGCGTCCGCATCG TGCTGACCGACAAGCGTCATTCTGACATCAGGCGTGAGGAACTGATGTATGACGGTGGCCTCGAGGCCTTCGTCGCCTAT CTCGACCGGGCGAAGAAACCGCTCGTGCAGAAGCCGGTCTCGATTAGAGGCGAGAAGGACGGCATCACCGTAGAGGTGGC CATGTGGTGGAACGACAGCTATCACGAGAACATGCTGTGCTTCACCAACAACATTCCGCAGCGTGACGGCGGCACGCATA TGGCCGGCTTCCGTGCCGCGCTCACGCGTCAGATCACCTCCTATGCCGACAGTTCCGGCGTCACCAAGAAGGAGAAGGTG TCGCTCACGGGCGACGATTGCCGAGAGGGCCTGACGGCTGTGCTGTCGGTTAAGGTCCCCGATCCCAAGTTCTCTTCGCA GACCAAGGACAAATTGGTGTCCTCCGAAGTCCGCCCGGTCGTCGAGAGCCTGGTCAACGAGGCCCTGGGCGTCTGGCTTG AAGAACATCCTTCCGACGCCAAGATTCTCGTGGGAAAGGTCGTCGAGGCCGCGGCCGCGCGCGAAGCGGCGCGCAAGGCG CGCGAACTGACGCGCCGGAAGGGTGCGCTCGACATCTCCTCGCTTCCCGGCAAGCTCGCCGATTGCTCGGAACGCGACCC GGCCAAGTCGGAACTCTTCCTGGTGGAGGGCGACTCGGCGGGCGGCTCCGCCAAACAGGGCCGCTCGCGCGAAAGCCAGG CGATCCTGCCGCTGCGAGGCAAGATCCTCAACGTCGAGCGCGCGCGTTTCGACAAGATGCTGTCGAGCCAGGAAATCGGC ACGCTGATCACCGCGCTCGGCACGTCGATCGGCCCGGACGAGTTCAATGCCGACAAGCTGCGCTATCACAAGATCATCAT CATGACGGATGCCGACGTCGACGGCGCTCACATCCGCACGCTGCTGCTCACCTTCTTCTTCCGGCAGATGCCGGTGCTGA TCGAGCGCGGCCACCTCTACATCGCCCAGCCGCCGCTCTATAAGGTGGCACGCGGCAAGTCCGTCCAGTATCTCAAGGAT GAGAAGGCGCTCGAAGACTACCTGATCAATATGGGCCTGGAGGAGGCTTCCCTCGAACTCGCTTCGGGCGAGGTGCGTGC CGGTCAGGATCTTCGCGAAGTCATCAACGACGCGCTCCGGCTGCGGTCGCTGATGGATGGGCTCCACTCCCGCTACAACC GCTCCGTCGTGGAGCAGGCTGCGATTGCCGGAGCGCTCAATGTGGAACTGAACGGCCAACGCAACGAATATCAGCAGATC GCCGCTGAAGTCGCCCGCCGGCTTGACGTCATCGCCGAGGAGACCGAGCGCGGCTGGGCGGCAGAGGTGACCGCCGAGGG CGGCCTGAAGCTGGAGCGCATGGTGCGCGGCGTCAAGGAAGCGGCTGTGCTCGACATGGCGCTGATCGGCTCGTCCGATG CCCGGCATATCGACCAGCTCAAGAGCCGGTTGAAGGAAGTCTACGGCGCACCGCCGATGCTGCGCCGCCGCGACGGAACG CAGGAGATCAGCGGCCCGCGCGCTCTTCTGGACGCGATCTTCGCCGCCGGCCGCAAGGGTCTTACCATGCAGCGCTACAA GGGCCTCGGCGAAATGAACGCCGAGCAGTTGTGGGAAACGACGCTCGATCCGAACGTTCGCTCGCTGCTGCAGGTCAAGG TAAACGACGCTACGGATGCGGACGGTCTGTTCTCGCGCCTGATGGGCGACGAAGTGGAACCGCGGCGCGACTTCATCCAG GAAAACGCGCTGAGCGTCGCCAACCTCGATATCTGA
Upstream 100 bases:
>100_bases TTTGGAACCGACGGACAAATTTCCTATAGTCCGCGAGGCATCTCGCGCTGTGATTCGCAATGGATCACGACGTCCGAAAC CTGGAAAGACCTGAGCTCGA
Downstream 100 bases:
>100_bases CATCTGATTCCAGCAAGCGGCTGCATAGCTTCGAAAGAGCAGGGCGGATCTCCGTCCTGCTTTTTCGTCGCTACGGCTCA TTCGCCCTTGAAGTGCCCTT
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 811; Mature: 810
Protein sequence:
>811_residues MTEISETEAGAIAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGHADLVTVTLNPDGSVT VTDNGRGIPTDIHREEGVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVSLKLKIRRSGKIHEMSFTHGVA DGPLKVTGDAGSDTGTEVTFTPSEQTFSNIEFEFARLEHRLRELAFLNSGVRIVLTDKRHSDIRREELMYDGGLEAFVAY LDRAKKPLVQKPVSIRGEKDGITVEVAMWWNDSYHENMLCFTNNIPQRDGGTHMAGFRAALTRQITSYADSSGVTKKEKV SLTGDDCREGLTAVLSVKVPDPKFSSQTKDKLVSSEVRPVVESLVNEALGVWLEEHPSDAKILVGKVVEAAAAREAARKA RELTRRKGALDISSLPGKLADCSERDPAKSELFLVEGDSAGGSAKQGRSRESQAILPLRGKILNVERARFDKMLSSQEIG TLITALGTSIGPDEFNADKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPVLIERGHLYIAQPPLYKVARGKSVQYLKD EKALEDYLINMGLEEASLELASGEVRAGQDLREVINDALRLRSLMDGLHSRYNRSVVEQAAIAGALNVELNGQRNEYQQI AAEVARRLDVIAEETERGWAAEVTAEGGLKLERMVRGVKEAAVLDMALIGSSDARHIDQLKSRLKEVYGAPPMLRRRDGT QEISGPRALLDAIFAAGRKGLTMQRYKGLGEMNAEQLWETTLDPNVRSLLQVKVNDATDADGLFSRLMGDEVEPRRDFIQ ENALSVANLDI
Sequences:
>Translated_811_residues MTEISETEAGAIAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGHADLVTVTLNPDGSVT VTDNGRGIPTDIHREEGVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVSLKLKIRRSGKIHEMSFTHGVA DGPLKVTGDAGSDTGTEVTFTPSEQTFSNIEFEFARLEHRLRELAFLNSGVRIVLTDKRHSDIRREELMYDGGLEAFVAY LDRAKKPLVQKPVSIRGEKDGITVEVAMWWNDSYHENMLCFTNNIPQRDGGTHMAGFRAALTRQITSYADSSGVTKKEKV SLTGDDCREGLTAVLSVKVPDPKFSSQTKDKLVSSEVRPVVESLVNEALGVWLEEHPSDAKILVGKVVEAAAAREAARKA RELTRRKGALDISSLPGKLADCSERDPAKSELFLVEGDSAGGSAKQGRSRESQAILPLRGKILNVERARFDKMLSSQEIG TLITALGTSIGPDEFNADKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPVLIERGHLYIAQPPLYKVARGKSVQYLKD EKALEDYLINMGLEEASLELASGEVRAGQDLREVINDALRLRSLMDGLHSRYNRSVVEQAAIAGALNVELNGQRNEYQQI AAEVARRLDVIAEETERGWAAEVTAEGGLKLERMVRGVKEAAVLDMALIGSSDARHIDQLKSRLKEVYGAPPMLRRRDGT QEISGPRALLDAIFAAGRKGLTMQRYKGLGEMNAEQLWETTLDPNVRSLLQVKVNDATDADGLFSRLMGDEVEPRRDFIQ ENALSVANLDI >Mature_810_residues TEISETEAGAIAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGHADLVTVTLNPDGSVTV TDNGRGIPTDIHREEGVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVSLKLKIRRSGKIHEMSFTHGVAD GPLKVTGDAGSDTGTEVTFTPSEQTFSNIEFEFARLEHRLRELAFLNSGVRIVLTDKRHSDIRREELMYDGGLEAFVAYL DRAKKPLVQKPVSIRGEKDGITVEVAMWWNDSYHENMLCFTNNIPQRDGGTHMAGFRAALTRQITSYADSSGVTKKEKVS LTGDDCREGLTAVLSVKVPDPKFSSQTKDKLVSSEVRPVVESLVNEALGVWLEEHPSDAKILVGKVVEAAAAREAARKAR ELTRRKGALDISSLPGKLADCSERDPAKSELFLVEGDSAGGSAKQGRSRESQAILPLRGKILNVERARFDKMLSSQEIGT LITALGTSIGPDEFNADKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPVLIERGHLYIAQPPLYKVARGKSVQYLKDE KALEDYLINMGLEEASLELASGEVRAGQDLREVINDALRLRSLMDGLHSRYNRSVVEQAAIAGALNVELNGQRNEYQQIA AEVARRLDVIAEETERGWAAEVTAEGGLKLERMVRGVKEAAVLDMALIGSSDARHIDQLKSRLKEVYGAPPMLRRRDGTQ EISGPRALLDAIFAAGRKGLTMQRYKGLGEMNAEQLWETTLDPNVRSLLQVKVNDATDADGLFSRLMGDEVEPRRDFIQE NALSVANLDI
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the type II topoisomerase family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=557, Percent_Identity=25.8527827648115, Blast_Score=130, Evalue=4e-30, Organism=Homo sapiens, GI19913406, Length=551, Percent_Identity=24.6823956442831, Blast_Score=129, Evalue=9e-30, Organism=Escherichia coli, GI48994957, Length=804, Percent_Identity=59.2039800995025, Blast_Score=905, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=556, Percent_Identity=42.0863309352518, Blast_Score=414, Evalue=1e-117, Organism=Caenorhabditis elegans, GI17535065, Length=542, Percent_Identity=24.7232472324723, Blast_Score=129, Evalue=7e-30, Organism=Caenorhabditis elegans, GI212645845, Length=519, Percent_Identity=23.3140655105973, Blast_Score=103, Evalue=5e-22, Organism=Caenorhabditis elegans, GI212645657, Length=141, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=597, Percent_Identity=25.7956448911223, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI17136538, Length=532, Percent_Identity=25.7518796992481, Blast_Score=132, Evalue=1e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 88838; Mature: 88707
Theoretical pI: Translated: 5.61; Mature: 5.61
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEISETEAGAIAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDE CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH ALAGHADLVTVTLNPDGSVTVTDNGRGIPTDIHREEGVSAAEVIMTQLHAGGKFDQNSYK HHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEE VSGGLHGVGVSVVNALSVSLKLKIRRSGKIHEMSFTHGVADGPLKVTGDAGSDTGTEVTF ECCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEHHCCCCCCCEEEECCCCCCCCCEEEE TPSEQTFSNIEFEFARLEHRLRELAFLNSGVRIVLTDKRHSDIRREELMYDGGLEAFVAY CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHH LDRAKKPLVQKPVSIRGEKDGITVEVAMWWNDSYHENMLCFTNNIPQRDGGTHMAGFRAA HHHHCCCHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHH LTRQITSYADSSGVTKKEKVSLTGDDCREGLTAVLSVKVPDPKFSSQTKDKLVSSEVRPV HHHHHHHHHCCCCCCCHHEEECCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH VESLVNEALGVWLEEHPSDAKILVGKVVEAAAAREAARKARELTRRKGALDISSLPGKLA HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC DCSERDPAKSELFLVEGDSAGGSAKQGRSRESQAILPLRGKILNVERARFDKMLSSQEIG CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHH TLITALGTSIGPDEFNADKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPVLIERGHLY HHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHEECCCEE IAQPPLYKVARGKSVQYLKDEKALEDYLINMGLEEASLELASGEVRAGQDLREVINDALR EECCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH LRSLMDGLHSRYNRSVVEQAAIAGALNVELNGQRNEYQQIAAEVARRLDVIAEETERGWA HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCE AEVTAEGGLKLERMVRGVKEAAVLDMALIGSSDARHIDQLKSRLKEVYGAPPMLRRRDGT EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCC QEISGPRALLDAIFAAGRKGLTMQRYKGLGEMNAEQLWETTLDPNVRSLLQVKVNDATDA CCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHEEEEECCCCCH DGLFSRLMGDEVEPRRDFIQENALSVANLDI HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC >Mature Secondary Structure TEISETEAGAIAEYGADSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDE CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH ALAGHADLVTVTLNPDGSVTVTDNGRGIPTDIHREEGVSAAEVIMTQLHAGGKFDQNSYK HHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEE VSGGLHGVGVSVVNALSVSLKLKIRRSGKIHEMSFTHGVADGPLKVTGDAGSDTGTEVTF ECCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEHHCCCCCCCEEEECCCCCCCCCEEEE TPSEQTFSNIEFEFARLEHRLRELAFLNSGVRIVLTDKRHSDIRREELMYDGGLEAFVAY CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHH LDRAKKPLVQKPVSIRGEKDGITVEVAMWWNDSYHENMLCFTNNIPQRDGGTHMAGFRAA HHHHCCCHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHH LTRQITSYADSSGVTKKEKVSLTGDDCREGLTAVLSVKVPDPKFSSQTKDKLVSSEVRPV HHHHHHHHHCCCCCCCHHEEECCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH VESLVNEALGVWLEEHPSDAKILVGKVVEAAAAREAARKARELTRRKGALDISSLPGKLA HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC DCSERDPAKSELFLVEGDSAGGSAKQGRSRESQAILPLRGKILNVERARFDKMLSSQEIG CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHH TLITALGTSIGPDEFNADKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPVLIERGHLY HHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHEECCCEE IAQPPLYKVARGKSVQYLKDEKALEDYLINMGLEEASLELASGEVRAGQDLREVINDALR EECCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH LRSLMDGLHSRYNRSVVEQAAIAGALNVELNGQRNEYQQIAAEVARRLDVIAEETERGWA HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCE AEVTAEGGLKLERMVRGVKEAAVLDMALIGSSDARHIDQLKSRLKEVYGAPPMLRRRDGT EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCC QEISGPRALLDAIFAAGRKGLTMQRYKGLGEMNAEQLWETTLDPNVRSLLQVKVNDATDA CCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCHHHHEEEEECCCCCH DGLFSRLMGDEVEPRRDFIQENALSVANLDI HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8226640 [H]