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The map label for this gene is birA [H]

Identifier: 150396127

GI number: 150396127

Start: 976175

End: 976942

Strand: Direct

Name: birA [H]

Synonym: Smed_0904

Alternate gene names: 150396127

Gene position: 976175-976942 (Clockwise)

Preceding gene: 150396126

Following gene: 150396128

Centisome position: 25.81

GC content: 65.62

Gene sequence:

>768_bases
TTGAGTGGCGGGCAGGGCAGCGGCCGGAATTCGCTTGAACAGTTCCGGCACGTCGCGCTCGCCGAAGCGGTTTCGACCAA
CAGCGAGTGCCTTTTGCGGGCGCGCGAGGGAGATGCCGGCAATCTCTGGATTACCGCGACGCGTCAGACCGGAGGCAGGG
GCCGGCGCGGCCGCGCCTGGTTCTCAGAACCGGGAAACCTTTACGCATCCCTGCTGCTCATCGATCCGGCGCCAACAGAC
AGACTGCACGCGCTGCCGCTGGCTGCCGCGGTAGCGGTTCATCGGGCGATCCGCAGGGTGATGCCGCCCGGCGGCGCCGA
GGCCGCAATCAAGTGGCCGAACGACATTCTGATCGACGGCAGAAAAACCTGCGGCATCCTTCTCGAAGGTGAAACCTTGC
CGGACGGGCGGCGCGCGCTGGTTATCGGCTGCGGCATCAACGTCGCCGTCATGCCGGAAGAAGCGCTTTACCCCGTCACA
TCGCTTCGGCAAGAGGGAGCGACAGTATCTCCCGAGGAGCTGTTCGCGCATCTTTTCGTGACCATGGCCGAGACGCTGGC
CGTCTGGGACCGGGGCGCCGGGGTCGGCGCGGTCATCGAGCAGTGGCGCGCGGCAGCCAAGGGGATCGGTGAGGCGATCA
CGGTCAACCTGCCCAACCGCTCGCTTTCCGGCCGCTTTGCGGGTATCGATCGAGACGGCCGGCTTATACTCGACACTGGT
TCCGGACCGCCGCAAACCATTGCGGCCGGCGACGTATTTTTTGGATGA

Upstream 100 bases:

>100_bases
TTCGGCTGGTGTTCGGCCTGTCGGGCCTCTTCGTGCTCGGCTATGTGCTCATCGGCGGCCCGCTTGGAAGCGCGGCCGAA
GCTGCGGCACGGACCTTCTT

Downstream 100 bases:

>100_bases
TTAAAAAGTAAAGGCGCATCACGACATGGCGCAGAATGAAGAATTGGTGTTCCTGCCGCTTGGCGGGGTGGGCGAAATAG
GCATGAATCTTGGCCTCTAC

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSGGQGSGRNSLEQFRHVALAEAVSTNSECLLRAREGDAGNLWITATRQTGGRGRRGRAWFSEPGNLYASLLLIDPAPTD
RLHALPLAAAVAVHRAIRRVMPPGGAEAAIKWPNDILIDGRKTCGILLEGETLPDGRRALVIGCGINVAVMPEEALYPVT
SLRQEGATVSPEELFAHLFVTMAETLAVWDRGAGVGAVIEQWRAAAKGIGEAITVNLPNRSLSGRFAGIDRDGRLILDTG
SGPPQTIAAGDVFFG

Sequences:

>Translated_255_residues
MSGGQGSGRNSLEQFRHVALAEAVSTNSECLLRAREGDAGNLWITATRQTGGRGRRGRAWFSEPGNLYASLLLIDPAPTD
RLHALPLAAAVAVHRAIRRVMPPGGAEAAIKWPNDILIDGRKTCGILLEGETLPDGRRALVIGCGINVAVMPEEALYPVT
SLRQEGATVSPEELFAHLFVTMAETLAVWDRGAGVGAVIEQWRAAAKGIGEAITVNLPNRSLSGRFAGIDRDGRLILDTG
SGPPQTIAAGDVFFG
>Mature_254_residues
SGGQGSGRNSLEQFRHVALAEAVSTNSECLLRAREGDAGNLWITATRQTGGRGRRGRAWFSEPGNLYASLLLIDPAPTDR
LHALPLAAAVAVHRAIRRVMPPGGAEAAIKWPNDILIDGRKTCGILLEGETLPDGRRALVIGCGINVAVMPEEALYPVTS
LRQEGATVSPEELFAHLFVTMAETLAVWDRGAGVGAVIEQWRAAAKGIGEAITVNLPNRSLSGRFAGIDRDGRLILDTGS
GPPQTIAAGDVFFG

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=219, Percent_Identity=30.1369863013699, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 26967; Mature: 26836

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGQGSGRNSLEQFRHVALAEAVSTNSECLLRAREGDAGNLWITATRQTGGRGRRGRAW
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC
FSEPGNLYASLLLIDPAPTDRLHALPLAAAVAVHRAIRRVMPPGGAEAAIKWPNDILIDG
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
RKTCGILLEGETLPDGRRALVIGCGINVAVMPEEALYPVTSLRQEGATVSPEELFAHLFV
CCEEEEEEECCCCCCCCEEEEEECCCEEEECCHHHHCCHHHHHHCCCCCCHHHHHHHHHH
TMAETLAVWDRGAGVGAVIEQWRAAAKGIGEAITVNLPNRSLSGRFAGIDRDGRLILDTG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCCEEEEECC
SGPPQTIAAGDVFFG
CCCCCEEECCCCCCC
>Mature Secondary Structure 
SGGQGSGRNSLEQFRHVALAEAVSTNSECLLRAREGDAGNLWITATRQTGGRGRRGRAW
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC
FSEPGNLYASLLLIDPAPTDRLHALPLAAAVAVHRAIRRVMPPGGAEAAIKWPNDILIDG
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
RKTCGILLEGETLPDGRRALVIGCGINVAVMPEEALYPVTSLRQEGATVSPEELFAHLFV
CCEEEEEEECCCCCCCCEEEEEECCCEEEECCHHHHCCHHHHHHCCCCCCHHHHHHHHHH
TMAETLAVWDRGAGVGAVIEQWRAAAKGIGEAITVNLPNRSLSGRFAGIDRDGRLILDTG
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCCEEEEECC
SGPPQTIAAGDVFFG
CCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]