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The map label for this gene is nuoC1 [H]

Identifier: 150396113

GI number: 150396113

Start: 961345

End: 961950

Strand: Direct

Name: nuoC1 [H]

Synonym: Smed_0890

Alternate gene names: 150396113

Gene position: 961345-961950 (Clockwise)

Preceding gene: 150396112

Following gene: 150396114

Centisome position: 25.42

GC content: 59.9

Gene sequence:

>606_bases
ATGAGTGAAGCCCTGAACGAGCTTGCCTCCTATATTCGCGAGGCGCGAGGCGCGCTGGTCGCCGGATCGGAAGTCAGATA
CGGCGAACTGACGCTGACGACGAAAGCCGAAAGCCTCATCGCGCTCCTGACTTTCCTGCGCGATGACGTCCAATGCGGCT
TCGTCAGTTTCATCGACGTCTGCGGGGTCGACTATCCGCAGCGGCCGGATCGCTTCGATGTCGTCTATCATCTTCTGTCG
CCACGCCAGAACCAGCGTATCCGCGTGAAGGTCGCGACCGGCGAGAACGAGCCGGTCCCCTCGATAACATCGGTCTATCC
GGGCGCCGACTGGTTCGAGCGCGAAGCCTACGACATGTATGGCATCCTCTTCACCGGCCACCCGGATCTGAGGCGCATCC
TTACGGATTACGGCTTCGAGGGCTATCCGCTGCGAAAGGATTTCCCGCTGACGGGCTTCGTCGAAGTGCGATACGACAAC
GAGGCCAAGCGCGTCGTCTACGAACCCGTCGAGCTGAAGCAGGAATTCCGCAATTTCGATTTTCTCTCGCCCTGGGAAGG
CACGGAATATGTGCTGCCGGGTGACGAGAAGGCGAAATCACGCTGA

Upstream 100 bases:

>100_bases
TCCTCCCACGGCAGAAGCGCTGCTTTACGGCGTGCTTCTGCTGCAGAAGAAGATCCGCCGGACCGGCACGATCGAGCGCT
AAGGGCAGGGGAACTTTGAC

Downstream 100 bases:

>100_bases
GTTAAGTCGGCCCGCGGCGATCCGCGAAGGACGCCGTCAGGCCTGGAGCAATCGGTATGACCGAACATAACGTCCGCAAC
TTCAACATCAACTTCGGCCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 1; NDH-1 subunit C 1 [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSEALNELASYIREARGALVAGSEVRYGELTLTTKAESLIALLTFLRDDVQCGFVSFIDVCGVDYPQRPDRFDVVYHLLS
PRQNQRIRVKVATGENEPVPSITSVYPGADWFEREAYDMYGILFTGHPDLRRILTDYGFEGYPLRKDFPLTGFVEVRYDN
EAKRVVYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKSR

Sequences:

>Translated_201_residues
MSEALNELASYIREARGALVAGSEVRYGELTLTTKAESLIALLTFLRDDVQCGFVSFIDVCGVDYPQRPDRFDVVYHLLS
PRQNQRIRVKVATGENEPVPSITSVYPGADWFEREAYDMYGILFTGHPDLRRILTDYGFEGYPLRKDFPLTGFVEVRYDN
EAKRVVYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKSR
>Mature_200_residues
SEALNELASYIREARGALVAGSEVRYGELTLTTKAESLIALLTFLRDDVQCGFVSFIDVCGVDYPQRPDRFDVVYHLLSP
RQNQRIRVKVATGENEPVPSITSVYPGADWFEREAYDMYGILFTGHPDLRRILTDYGFEGYPLRKDFPLTGFVEVRYDNE
AKRVVYEPVELKQEFRNFDFLSPWEGTEYVLPGDEKAKSR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=186, Percent_Identity=52.6881720430108, Blast_Score=202, Evalue=1e-52,
Organism=Escherichia coli, GI145693162, Length=175, Percent_Identity=34.8571428571429, Blast_Score=101, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=50.2702702702703, Blast_Score=189, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=50.2702702702703, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=51.9125683060109, Blast_Score=199, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23111; Mature: 22980

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALNELASYIREARGALVAGSEVRYGELTLTTKAESLIALLTFLRDDVQCGFVSFIDV
CHHHHHHHHHHHHHHCCCEEECCCEEECEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHH
CGVDYPQRPDRFDVVYHLLSPRQNQRIRVKVATGENEPVPSITSVYPGADWFEREAYDMY
HCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHEE
GILFTGHPDLRRILTDYGFEGYPLRKDFPLTGFVEVRYDNEAKRVVYEPVELKQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHCCC
FLSPWEGTEYVLPGDEKAKSR
CCCCCCCCEEEECCCHHCCCC
>Mature Secondary Structure 
SEALNELASYIREARGALVAGSEVRYGELTLTTKAESLIALLTFLRDDVQCGFVSFIDV
HHHHHHHHHHHHHHCCCEEECCCEEECEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHH
CGVDYPQRPDRFDVVYHLLSPRQNQRIRVKVATGENEPVPSITSVYPGADWFEREAYDMY
HCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHEE
GILFTGHPDLRRILTDYGFEGYPLRKDFPLTGFVEVRYDNEAKRVVYEPVELKQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHCCC
FLSPWEGTEYVLPGDEKAKSR
CCCCCCCCEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]