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The map label for this gene is nuoD1 [H]

Identifier: 150396114

GI number: 150396114

Start: 962007

End: 963197

Strand: Direct

Name: nuoD1 [H]

Synonym: Smed_0891

Alternate gene names: 150396114

Gene position: 962007-963197 (Clockwise)

Preceding gene: 150396113

Following gene: 150396115

Centisome position: 25.44

GC content: 62.13

Gene sequence:

>1191_bases
ATGACCGAACATAACGTCCGCAACTTCAACATCAACTTCGGCCCGCAGCATCCGGCGGCGCACGGCGTTCTGCGTCTGGT
GCTGGAGCTTGACGGCGAGATCGTCGAGCGTGTCGACCCGCATATAGGCCTTTTGCATCGCGGCACGGAGAAGCTGATCG
AGGCCAAGACCTATCTGCAGGCGATTCCTTATTTCGACCGGCTCGACTATGTCGCGCCGATGAACCAGGAGCACGCTTTC
GCGCTTGCAGTGGAGAGGTTGACGGGCACGCAGGTGCCGATCCGCGGTCAGCTGATCCGGGTTCTCTATTCCGAGATCGG
TCGTATCCTTTCGCACCTCCTCAATGTGACCACCCAGGCCATGGATGTCGGCGCGCTTACCCCGCCGCTCTGGGGCTTCG
AGGAGCGCGAGAAGCTGATGGTCTTTTACGAGCGCGCCTGCGGCGCGCGCATGCATGCCGCATATTTCCGCCCGGGCGGC
GTGCACCAGGATCTGCCGCATCAACTGGTCGAGGATATCGGCAAGTGGATCGACCCGTTCCTGAAGACCGTCGACGATAT
CGACGAGCTTCTGACCGGCAACCGCATCTTCAAGCAGCGCAACGTCGATATCGGCGTCGTCAGCCTGGAAGACGCCTGGG
CCTGGGGTTTCTCGGGCGTCATGGTGCGCGGCTCGGGCGCGGCCTGGGACCTGCGCCGTTCGCAGCCCTATGAATGCTAT
TCCGACCTGGAGTTCGACATTCCGATCGGCAAGAACGGCGATTGCTTCGACCGTTATCTCATCCGGATGATCGAGATGCG
GGAGTCCGCCCGCATCATGCGCCAATGCGTCGATCGCCTGCTGGGCGATGCCAAGGTCGGTCCGGTCTCCTCGCTCGACG
GCAAGATCGTGCCGCCGAAGCGGGGCGAGATGAAGCGGTCGATGGAGGCGCTGATCCATCACTTCAAGCTCTACACCGAG
GGCTATCACGTGCCGGCCGGCGACGTTTATGCCGCGGTCGAGGCGCCCAAGGGCGAGTTCGGCGTCTATCTCGTATCCGA
CGGCACCAACAAGCCCTACCGCTGCAAGATACGTGCACCGGGCTACGCCCATCTTCAGGCGATGGATTTCCTCTGTCGCG
GACACCAGCTTGCCGATGTTTCGGCCGTGCTGGGCTCTCTCGATATCGTTTTCGGCGAGGTGGATCGCTGA

Upstream 100 bases:

>100_bases
CGGAATATGTGCTGCCGGGTGACGAGAAGGCGAAATCACGCTGAGTTAAGTCGGCCCGCGGCGATCCGCGAAGGACGCCG
TCAGGCCTGGAGCAATCGGT

Downstream 100 bases:

>100_bases
TGCGTCTGGTGCCGCTCGCCGCCGTCGGACTTCTTGCGCTCGTCTCCGGCGCCTCGGCCCAGGAGGACGTCGGCAGCGAG
TCGTCGGCTGGGATGCGGGG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D 1; NDH-1 subunit D 1 [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTEHNVRNFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQAIPYFDRLDYVAPMNQEHAF
ALAVERLTGTQVPIRGQLIRVLYSEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGG
VHQDLPHQLVEDIGKWIDPFLKTVDDIDELLTGNRIFKQRNVDIGVVSLEDAWAWGFSGVMVRGSGAAWDLRRSQPYECY
SDLEFDIPIGKNGDCFDRYLIRMIEMRESARIMRQCVDRLLGDAKVGPVSSLDGKIVPPKRGEMKRSMEALIHHFKLYTE
GYHVPAGDVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAPGYAHLQAMDFLCRGHQLADVSAVLGSLDIVFGEVDR

Sequences:

>Translated_396_residues
MTEHNVRNFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQAIPYFDRLDYVAPMNQEHAF
ALAVERLTGTQVPIRGQLIRVLYSEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGG
VHQDLPHQLVEDIGKWIDPFLKTVDDIDELLTGNRIFKQRNVDIGVVSLEDAWAWGFSGVMVRGSGAAWDLRRSQPYECY
SDLEFDIPIGKNGDCFDRYLIRMIEMRESARIMRQCVDRLLGDAKVGPVSSLDGKIVPPKRGEMKRSMEALIHHFKLYTE
GYHVPAGDVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAPGYAHLQAMDFLCRGHQLADVSAVLGSLDIVFGEVDR
>Mature_395_residues
TEHNVRNFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQAIPYFDRLDYVAPMNQEHAFA
LAVERLTGTQVPIRGQLIRVLYSEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGGV
HQDLPHQLVEDIGKWIDPFLKTVDDIDELLTGNRIFKQRNVDIGVVSLEDAWAWGFSGVMVRGSGAAWDLRRSQPYECYS
DLEFDIPIGKNGDCFDRYLIRMIEMRESARIMRQCVDRLLGDAKVGPVSSLDGKIVPPKRGEMKRSMEALIHHFKLYTEG
YHVPAGDVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAPGYAHLQAMDFLCRGHQLADVSAVLGSLDIVFGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=391, Percent_Identity=62.9156010230179, Blast_Score=515, Evalue=1e-146,
Organism=Homo sapiens, GI260898743, Length=385, Percent_Identity=62.0779220779221, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI145693162, Length=387, Percent_Identity=37.984496124031, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1789076, Length=391, Percent_Identity=26.3427109974425, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788832, Length=388, Percent_Identity=25.2577319587629, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17555284, Length=394, Percent_Identity=59.8984771573604, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17568379, Length=394, Percent_Identity=59.1370558375635, Blast_Score=498, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24638644, Length=394, Percent_Identity=61.1675126903553, Blast_Score=523, Evalue=1e-149,
Organism=Drosophila melanogaster, GI221459469, Length=395, Percent_Identity=54.1772151898734, Blast_Score=461, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 44673; Mature: 44542

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00535 COMPLEX1_49K ; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHNVRNFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQ
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
AIPYFDRLDYVAPMNQEHAFALAVERLTGTQVPIRGQLIRVLYSEIGRILSHLLNVTTQA
HCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGGVHQDLPHQLVEDIGKWIDPF
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LKTVDDIDELLTGNRIFKQRNVDIGVVSLEDAWAWGFSGVMVRGSGAAWDLRRSQPYECY
HHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCHHCCCCCEEEECCCCEEECCCCCCCCHH
SDLEFDIPIGKNGDCFDRYLIRMIEMRESARIMRQCVDRLLGDAKVGPVSSLDGKIVPPK
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCC
RGEMKRSMEALIHHFKLYTEGYHVPAGDVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
GYAHLQAMDFLCRGHQLADVSAVLGSLDIVFGEVDR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure 
TEHNVRNFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQ
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
AIPYFDRLDYVAPMNQEHAFALAVERLTGTQVPIRGQLIRVLYSEIGRILSHLLNVTTQA
HCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGGVHQDLPHQLVEDIGKWIDPF
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LKTVDDIDELLTGNRIFKQRNVDIGVVSLEDAWAWGFSGVMVRGSGAAWDLRRSQPYECY
HHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCHHCCCCCEEEECCCCEEECCCCCCCCHH
SDLEFDIPIGKNGDCFDRYLIRMIEMRESARIMRQCVDRLLGDAKVGPVSSLDGKIVPPK
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCC
RGEMKRSMEALIHHFKLYTEGYHVPAGDVYAAVEAPKGEFGVYLVSDGTNKPYRCKIRAP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
GYAHLQAMDFLCRGHQLADVSAVLGSLDIVFGEVDR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA