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The map label for this gene is rhtC [C]

Identifier: 150395813

GI number: 150395813

Start: 637606

End: 638244

Strand: Direct

Name: rhtC [C]

Synonym: Smed_0589

Alternate gene names: 150395813

Gene position: 637606-638244 (Clockwise)

Preceding gene: 150395811

Following gene: 150395814

Centisome position: 16.86

GC content: 62.28

Gene sequence:

>639_bases
ATGACCTACGCGGAAAACCTCTGGCTTTTTTTCAGCCTTCTCTTCGGCATCATCATCGTTCCCGGCATGGATATGGTGTT
TGTCCTCGCAAATGCGCTGACCGGCGGGCGCGCCTCCGGGCTTTCGGCAACGGTTGGCATCATGGCGGGAGGCGTGCTGC
ACACGCTCTATGCGGCCCTGGGTGTCAGCGTCATCCTGCATCTGGTGCCTCAGCTCTATAATCTGCTGCTTGTGGCCGGA
GCGGCCTACATCGCCTGGATCGGGTTTTCGCTTCTACGCAGTTCCATCAAGATCAGCGGCGTAGCGGCCGGCGCTCGGTT
GACGCGCTGGGCAAGCTTTCGGCAGGGAGCGCTGACGAGCCTGATGAATCCCAAGGCCTATCTCTTCATGCTTGCCGTCT
ACCCGCAGTTCCTGAAGCCGCAATTCGGCCCGGTCTGGTCCCAGGCAGCCGTCATGGCCCTGATGATCGCGCTGACGCAG
CTCGCGGTCTATGGCGGTCTTGCGCTTGCGGCCGGACGTGGACGTGACTTCCTGGTCGGCAGCCCCGGTGCCACCGTTGC
GATCGGTCGCTTCGCCGGTCTCCTGCTCCTCGTAATCGCGGTCTTTACGGTCTGGCATGGCTGGAGCGGGGAGGTTTGA

Upstream 100 bases:

>100_bases
ACACGACCTTGTCAGTTGGAGGGAGGTATATCACGCGCCAACGGATTGAAACCAAACAATCCGCCGCCGAGATAGCACCG
AAACGGGACGAGCAACTGAC

Downstream 100 bases:

>100_bases
GTCGCCGCCGTCAAGTATCAAAGGTGAGTATCTTATTCATGTATTTAAATATGGCGCAGAGAAATACGGTTCGGCGCTGC
GAATTATGCTGCAACGACAA

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTYAENLWLFFSLLFGIIIVPGMDMVFVLANALTGGRASGLSATVGIMAGGVLHTLYAALGVSVILHLVPQLYNLLLVAG
AAYIAWIGFSLLRSSIKISGVAAGARLTRWASFRQGALTSLMNPKAYLFMLAVYPQFLKPQFGPVWSQAAVMALMIALTQ
LAVYGGLALAAGRGRDFLVGSPGATVAIGRFAGLLLLVIAVFTVWHGWSGEV

Sequences:

>Translated_212_residues
MTYAENLWLFFSLLFGIIIVPGMDMVFVLANALTGGRASGLSATVGIMAGGVLHTLYAALGVSVILHLVPQLYNLLLVAG
AAYIAWIGFSLLRSSIKISGVAAGARLTRWASFRQGALTSLMNPKAYLFMLAVYPQFLKPQFGPVWSQAAVMALMIALTQ
LAVYGGLALAAGRGRDFLVGSPGATVAIGRFAGLLLLVIAVFTVWHGWSGEV
>Mature_211_residues
TYAENLWLFFSLLFGIIIVPGMDMVFVLANALTGGRASGLSATVGIMAGGVLHTLYAALGVSVILHLVPQLYNLLLVAGA
AYIAWIGFSLLRSSIKISGVAAGARLTRWASFRQGALTSLMNPKAYLFMLAVYPQFLKPQFGPVWSQAAVMALMIALTQL
AVYGGLALAAGRGRDFLVGSPGATVAIGRFAGLLLLVIAVFTVWHGWSGEV

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=143, Percent_Identity=31.4685314685315, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788099, Length=135, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI48994979, Length=194, Percent_Identity=25.7731958762887, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22392; Mature: 22261

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAENLWLFFSLLFGIIIVPGMDMVFVLANALTGGRASGLSATVGIMAGGVLHTLYAAL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GVSVILHLVPQLYNLLLVAGAAYIAWIGFSLLRSSIKISGVAAGARLTRWASFRQGALTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMNPKAYLFMLAVYPQFLKPQFGPVWSQAAVMALMIALTQLAVYGGLALAAGRGRDFLVG
HCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SPGATVAIGRFAGLLLLVIAVFTVWHGWSGEV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TYAENLWLFFSLLFGIIIVPGMDMVFVLANALTGGRASGLSATVGIMAGGVLHTLYAAL
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GVSVILHLVPQLYNLLLVAGAAYIAWIGFSLLRSSIKISGVAAGARLTRWASFRQGALTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMNPKAYLFMLAVYPQFLKPQFGPVWSQAAVMALMIALTQLAVYGGLALAAGRGRDFLVG
HCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SPGATVAIGRFAGLLLLVIAVFTVWHGWSGEV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8169201; 10984043 [H]