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The map label for this gene is mas [H]

Identifier: 150395792

GI number: 150395792

Start: 617028

End: 618029

Strand: Direct

Name: mas [H]

Synonym: Smed_0568

Alternate gene names: 150395792

Gene position: 617028-618029 (Clockwise)

Preceding gene: 150395791

Following gene: 150395794

Centisome position: 16.32

GC content: 64.17

Gene sequence:

>1002_bases
ATGACCCTTCCGACAGAAATGACCTATGTCGATCTGCCTGGCCCCGGAGGGCCGGAGAATATGGTGCTGGCGCGAGGGGC
GATGCCCGAGGTCCGGACCGGCGACATTCTGGTCCGCGTCGAAGCCTTCGGCATCAATCGGCCCGACGTCCTGCAGCGCA
AGGGAGACTACCCGCTGCCCGCTGGGGCGAGCCCCATCCTCGGGCTCGAAGTTGCAGGCGAGGTGGTTGCGCTCGGCCAC
GGCGCGAGCGGTTTCTCTATCGGCGACAGAGTCTGCGCTCTCGCCAATGGCGGCGCCTATGCGGAATATTGCGCCGTCCC
CGCCACGCAGGCACTTCTCTGGCCCAAGGGATACGATGCCGTGAAGGCTGCAGCCTTGCCCGAGACCTTCTTTACCGTCT
GGGCCAACGTCTTCGACATGGCAGGCCTGAAGTCAGGTGAAACATTTCTCGTCCATGGCGGATCGAGCGGCATCGGCACG
ACGGCTATTCAGCTTGCGAAAGCTCTCGGTGCGGAGGTTTTCGCAACCGCCGGCAGCGCGGCCAAGTGCAAGGCATGTGA
GGCGCTCGGGGCGAAACGCGCGATCAACTATCGTGAGGAGGATTTCAGGGCTGTCGTGCTGGAAGAGACCGGCGGCCGCG
GTGCCGACGTCATTCTTGACATGGTCGGTGGACCCTATTTCGAGCGCAACATCGGCAGCCTCGCCAAGGATGGGCGTCTG
TCCATCATTGCTTTCCTCGGCGGGGCGCGGGTGGAGGGCGGCAATATCGCGCCGATCCTCATGAAGCGGCTGCGTATAAT
GGGCTCGTTGCTCCGGCCCCGCACCGCCGCCGAGAAGCAGGCCATCCGTGATGGGCTCGCGGCAAGGGTCTGGCCGTTGC
TCGAGGGGGGCGAAGTTGCTCCTGTCGTGCAGGCCGTCCTGCCGTTCGAGGAGATTTCCGACGCACATCGGCTCATGGAG
CAGGGCGATCATATCGGCAAGATCGTGATGCGGATCGGGTAG

Upstream 100 bases:

>100_bases
AGCCGCTCGACCGTACCTGAGCGGATGGATGCGAGGCGATCTTTCCCGAACGGCGAGAGGGCTATAGGTATAGGCGGAAC
CGTTTTGCGAGGATGCCGTC

Downstream 100 bases:

>100_bases
CAAAACACAATAAGACGATGGTCGCCCTTGTATCGGTGCAAGGATCGATTACGTTATGTTCAACGTCAACGAACAGAAAG
GAAGGTGATCCAATGTCTAA

Product: quinone oxidoreductase putative PIG3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTLPTEMTYVDLPGPGGPENMVLARGAMPEVRTGDILVRVEAFGINRPDVLQRKGDYPLPAGASPILGLEVAGEVVALGH
GASGFSIGDRVCALANGGAYAEYCAVPATQALLWPKGYDAVKAAALPETFFTVWANVFDMAGLKSGETFLVHGGSSGIGT
TAIQLAKALGAEVFATAGSAAKCKACEALGAKRAINYREEDFRAVVLEETGGRGADVILDMVGGPYFERNIGSLAKDGRL
SIIAFLGGARVEGGNIAPILMKRLRIMGSLLRPRTAAEKQAIRDGLAARVWPLLEGGEVAPVVQAVLPFEEISDAHRLME
QGDHIGKIVMRIG

Sequences:

>Translated_333_residues
MTLPTEMTYVDLPGPGGPENMVLARGAMPEVRTGDILVRVEAFGINRPDVLQRKGDYPLPAGASPILGLEVAGEVVALGH
GASGFSIGDRVCALANGGAYAEYCAVPATQALLWPKGYDAVKAAALPETFFTVWANVFDMAGLKSGETFLVHGGSSGIGT
TAIQLAKALGAEVFATAGSAAKCKACEALGAKRAINYREEDFRAVVLEETGGRGADVILDMVGGPYFERNIGSLAKDGRL
SIIAFLGGARVEGGNIAPILMKRLRIMGSLLRPRTAAEKQAIRDGLAARVWPLLEGGEVAPVVQAVLPFEEISDAHRLME
QGDHIGKIVMRIG
>Mature_332_residues
TLPTEMTYVDLPGPGGPENMVLARGAMPEVRTGDILVRVEAFGINRPDVLQRKGDYPLPAGASPILGLEVAGEVVALGHG
ASGFSIGDRVCALANGGAYAEYCAVPATQALLWPKGYDAVKAAALPETFFTVWANVFDMAGLKSGETFLVHGGSSGIGTT
AIQLAKALGAEVFATAGSAAKCKACEALGAKRAINYREEDFRAVVLEETGGRGADVILDMVGGPYFERNIGSLAKDGRLS
IIAFLGGARVEGGNIAPILMKRLRIMGSLLRPRTAAEKQAIRDGLAARVWPLLEGGEVAPVVQAVLPFEEISDAHRLMEQ
GDHIGKIVMRIG

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=39.3939393939394, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=39.3939393939394, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI194239674, Length=322, Percent_Identity=29.8136645962733, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI13236495, Length=322, Percent_Identity=29.8136645962733, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=28.7539936102236, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=27.4566473988439, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI28557745, Length=335, Percent_Identity=31.3432835820896, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI194239676, Length=322, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI41872631, Length=231, Percent_Identity=30.7359307359307, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI47519420, Length=364, Percent_Identity=25.2747252747253, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=31.8885448916409, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790045, Length=252, Percent_Identity=28.1746031746032, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=319, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=306, Percent_Identity=25.8169934640523, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=25.8823529411765, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=276, Percent_Identity=25.3623188405797, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=24.3975903614458, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=277, Percent_Identity=25.6317689530686, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=22.8915662650602, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=277, Percent_Identity=30.6859205776173, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19920632, Length=306, Percent_Identity=29.0849673202614, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI221330659, Length=306, Percent_Identity=29.0849673202614, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34897; Mature: 34766

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPTEMTYVDLPGPGGPENMVLARGAMPEVRTGDILVRVEAFGINRPDVLQRKGDYPLP
CCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCC
AGASPILGLEVAGEVVALGHGASGFSIGDRVCALANGGAYAEYCAVPATQALLWPKGYDA
CCCCCEEEHEECCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCCHHHEECCCCCHH
VKAAALPETFFTVWANVFDMAGLKSGETFLVHGGSSGIGTTAIQLAKALGAEVFATAGSA
HHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHCCCCC
AKCKACEALGAKRAINYREEDFRAVVLEETGGRGADVILDMVGGPYFERNIGSLAKDGRL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEHHCCCHHHHHHHHHCCCCCE
SIIAFLGGARVEGGNIAPILMKRLRIMGSLLRPRTAAEKQAIRDGLAARVWPLLEGGEVA
EEEEEECCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHCCCCCHH
PVVQAVLPFEEISDAHRLMEQGDHIGKIVMRIG
HHHHHHHCHHHHHHHHHHHHCCCCHHHEEEECC
>Mature Secondary Structure 
TLPTEMTYVDLPGPGGPENMVLARGAMPEVRTGDILVRVEAFGINRPDVLQRKGDYPLP
CCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCCCCC
AGASPILGLEVAGEVVALGHGASGFSIGDRVCALANGGAYAEYCAVPATQALLWPKGYDA
CCCCCEEEHEECCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCCHHHEECCCCCHH
VKAAALPETFFTVWANVFDMAGLKSGETFLVHGGSSGIGTTAIQLAKALGAEVFATAGSA
HHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHCCCCC
AKCKACEALGAKRAINYREEDFRAVVLEETGGRGADVILDMVGGPYFERNIGSLAKDGRL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEHHCCCHHHHHHHHHCCCCCE
SIIAFLGGARVEGGNIAPILMKRLRIMGSLLRPRTAAEKQAIRDGLAARVWPLLEGGEVA
EEEEEECCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHCCCCCHH
PVVQAVLPFEEISDAHRLMEQGDHIGKIVMRIG
HHHHHHHCHHHHHHHHHHHHCCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]