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The map label for this gene is guaB [C]

Identifier: 150401626

GI number: 150401626

Start: 1272544

End: 1273491

Strand: Direct

Name: guaB [C]

Synonym: Maeo_1203

Alternate gene names: 150401626

Gene position: 1272544-1273491 (Clockwise)

Preceding gene: 150401625

Following gene: 150401627

Centisome position: 81.08

GC content: 31.96

Gene sequence:

>948_bases
ATGCTTTTTAAAAAACTTTCAACTGTTGAGCGAGTATATAATATTGGATTAGAATATAATAATTTAAGATATTTATTTAA
AAGCATAACTGCTGTTGTATTGGACGCAGAGGACGATTTGGCAAAATTGTATGATTTAAAGGTCCTCGATAAAATACCGG
TAAAGGAGATAATGACAAAAGACCTTGTCTCGATTAATGAATCTGAAACAGCTAAACAGCTGATAAAATACATTGAAAAA
TATAGGCATATGGGGTATCCAGTCATAGATAACAATAATAAATTGGTCGGAGTGGTTACATTTAATGATTTAGAGAAGGG
ACATGCAATTATTAGAGATATAATGACTCCAAAAGAAAAGCTTATAACAATTATGCCCGATACTTCGGCATCAGAATCTC
AAAATATAATGGCAAATAATGATATTGGTAGGTTGTTGGTTGTCGATGATAATGGGGAGCTCCTTGGTTTGGTGAGTAGG
GGGGACATTGTAAAAACATATAGGACCTACGGTAAAAAGACGAAAATCCAAAAATGTGATAGACTCACAATTATGCACTT
CTACGATGAGGAGAAAGAGAAAAAACTAAAAAAATTGACGGATGATTTGGTCGTTCTTCTTGGGGGTAGGGGCTATAATG
TATCTGAAAAAGAAGAATATATTGAGATACTGACAAAAGATTGGGAACCATTATCCAAAATCGTGTATAATAATGGGAAA
CCAGACCATCTGTCATTAACAACCAGAACAATAGATATAACGAATATGAAAATAATTGAAGAAATATTAAATACAATAGA
AAAATACAAAATTGAAGAAATTGTAATAACTGACCATATTAGGCTTATAGACGAAAAATCTTCTATTCAGAGAATTATAA
CAGATATGACCTCATTCAGAGATAGTGAAAAAACTTTTGGGACTATTACTATAAGGTCTGACTTCTAA

Upstream 100 bases:

>100_bases
ATGCTAATTTTATGACTTATCAGAATAAATTACTTCGGAATTAATTGGACACACCATAAATATGAATTTAACTAGATAAT
TTTATATGTGGGTGATACTT

Downstream 100 bases:

>100_bases
TTATGACCATCTACTAACGACAATTGAACAAAATCCTTCGGATTTTTGACACCTATTTTTATATAATATTTTATAATATT
TTTTATAGATTAGATTGTAG

Product: signal transduction protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: Peptidase M; Cl- Channel Voltage-Gated Family Protein; Polynucleotide Adenylyltransferase Region; Metalloprotease; PolyA Polymerase Family Protein; Signal Transduction Protein; CBS Domain Containing Protein; Signal Transduction Protein With CBS Domains; Chloride Channel Core; SpoIVFB-Type Metallopeptidase; Cl- Channel Voltage Gated; Chloride Channel; Peptidase; Zn-Dependent Protease; tRNA Nucleotidyltransferase/Poly(A) Polymerase; Inosine-5-Monophosphate Dehydrogenase; Poly A Polymerase

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLFKKLSTVERVYNIGLEYNNLRYLFKSITAVVLDAEDDLAKLYDLKVLDKIPVKEIMTKDLVSINESETAKQLIKYIEK
YRHMGYPVIDNNNKLVGVVTFNDLEKGHAIIRDIMTPKEKLITIMPDTSASESQNIMANNDIGRLLVVDDNGELLGLVSR
GDIVKTYRTYGKKTKIQKCDRLTIMHFYDEEKEKKLKKLTDDLVVLLGGRGYNVSEKEEYIEILTKDWEPLSKIVYNNGK
PDHLSLTTRTIDITNMKIIEEILNTIEKYKIEEIVITDHIRLIDEKSSIQRIITDMTSFRDSEKTFGTITIRSDF

Sequences:

>Translated_315_residues
MLFKKLSTVERVYNIGLEYNNLRYLFKSITAVVLDAEDDLAKLYDLKVLDKIPVKEIMTKDLVSINESETAKQLIKYIEK
YRHMGYPVIDNNNKLVGVVTFNDLEKGHAIIRDIMTPKEKLITIMPDTSASESQNIMANNDIGRLLVVDDNGELLGLVSR
GDIVKTYRTYGKKTKIQKCDRLTIMHFYDEEKEKKLKKLTDDLVVLLGGRGYNVSEKEEYIEILTKDWEPLSKIVYNNGK
PDHLSLTTRTIDITNMKIIEEILNTIEKYKIEEIVITDHIRLIDEKSSIQRIITDMTSFRDSEKTFGTITIRSDF
>Mature_315_residues
MLFKKLSTVERVYNIGLEYNNLRYLFKSITAVVLDAEDDLAKLYDLKVLDKIPVKEIMTKDLVSINESETAKQLIKYIEK
YRHMGYPVIDNNNKLVGVVTFNDLEKGHAIIRDIMTPKEKLITIMPDTSASESQNIMANNDIGRLLVVDDNGELLGLVSR
GDIVKTYRTYGKKTKIQKCDRLTIMHFYDEEKEKKLKKLTDDLVVLLGGRGYNVSEKEEYIEILTKDWEPLSKIVYNNGK
PDHLSLTTRTIDITNMKIIEEILNTIEKYKIEEIVITDHIRLIDEKSSIQRIITDMTSFRDSEKTFGTITIRSDF

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 36426; Mature: 36426

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKKLSTVERVYNIGLEYNNLRYLFKSITAVVLDAEDDLAKLYDLKVLDKIPVKEIMTK
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHH
DLVSINESETAKQLIKYIEKYRHMGYPVIDNNNKLVGVVTFNDLEKGHAIIRDIMTPKEK
HHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCHHHHHHHHHHCCCHHH
LITIMPDTSASESQNIMANNDIGRLLVVDDNGELLGLVSRGDIVKTYRTYGKKTKIQKCD
EEEEECCCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHCC
RLTIMHFYDEEKEKKLKKLTDDLVVLLGGRGYNVSEKEEYIEILTKDWEPLSKIVYNNGK
CEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCC
PDHLSLTTRTIDITNMKIIEEILNTIEKYKIEEIVITDHIRLIDEKSSIQRIITDMTSFR
CCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECHHHEECCHHHHHHHHHHHHHCC
DSEKTFGTITIRSDF
CCCCCEEEEEEEECC
>Mature Secondary Structure
MLFKKLSTVERVYNIGLEYNNLRYLFKSITAVVLDAEDDLAKLYDLKVLDKIPVKEIMTK
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCHHHHHHH
DLVSINESETAKQLIKYIEKYRHMGYPVIDNNNKLVGVVTFNDLEKGHAIIRDIMTPKEK
HHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCHHHHHHHHHHCCCHHH
LITIMPDTSASESQNIMANNDIGRLLVVDDNGELLGLVSRGDIVKTYRTYGKKTKIQKCD
EEEEECCCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHCC
RLTIMHFYDEEKEKKLKKLTDDLVVLLGGRGYNVSEKEEYIEILTKDWEPLSKIVYNNGK
CEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCC
PDHLSLTTRTIDITNMKIIEEILNTIEKYKIEEIVITDHIRLIDEKSSIQRIITDMTSFR
CCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECHHHEECCHHHHHHHHHHHHHCC
DSEKTFGTITIRSDF
CCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA