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The map label for this gene is 150401587

Identifier: 150401587

GI number: 150401587

Start: 1221404

End: 1222492

Strand: Direct

Name: 150401587

Synonym: Maeo_1164

Alternate gene names: NA

Gene position: 1221404-1222492 (Clockwise)

Preceding gene: 150401586

Following gene: 150401588

Centisome position: 77.82

GC content: 32.51

Gene sequence:

>1089_bases
ATGAAATTTGGATGGATAATGGCAAATGATGAGGATTGGGAAGAAAGAAAAGAAACAGTAAAAGATTCCCTTGAAAGTTC
AATACCTGCTGTGATGGTTTATGAAGAAGATATTGAAAAAGTTAAAGAATTAGGAAATATTAAAACAATATCTAAAAATC
CAAATTCTGACATCGTAGTAATCGATAAAGGCGACGATTTAACTATTTTATTTGATGCAAAAAAAGAAGGAAAGGAAACT
GGCGTATTTATCTCTATCGAATGTAAAGAGGATGAGGAATACGCATCAGAGGTAAGTAGATACGATTATGTGGATTACAT
AATATTAGAGGGAAAAGATTGGAATATTATCCCATTGGAAAATTTAATTGCTGATTTATTTGATGAAAATATAAAAATAG
TTTCATTGGCAAAAGATATAAATGATGCAAGAACAGCTTATGAAATACTTGAAAGGGGAGTTGATGGAGTTCTTTATGTC
CCAAAAGATATAAATGATGTAAAAGACTTTGCAACATTAATTGAAAAAATGAATTCTGAAAAGTTGGATTTAGATTGTGC
TACAATTACGAAAGTTGAGGCTATTGGAAGTGGGGATAGAGTTTGTATAGATACATGCTCAATGATGGAAATGGGAGAAG
GTATGCTCATAGGCTCATATTCTAGGGCTTTATTTTTGGTGCATGCTGAAACTGTGGAAAATCCTTATGTTGCCACACGA
CCATTTAGAGTAAATGCAGGTCCTGTTCATGCCTATGTATTATGCACTGGAAACAAAACAAGATATTTAAGTGAATTAAA
AGCTGGCGATGGGATATTGATTGTAGATAAAGATGGAATGACAAGAGAGGGAATTGTAGGCAGAGTAAAAATAGAAAAAA
GACCTTTGATGTTAATTGAAGCTGAATATGTGGGGGGGGAAATTGTAAGAACCATAGTACAAAATGCTGAAACAATCAGA
TTGGTTAATGAAAATGGAGCTCCTATATCTGTGGTAGATTTGAAGGTGGGCGATAAAGTAAAATTAAAAATAGATACTAA
TGCTAGACATTTTGGAATGGCTATACAAGAAACAATAATTGAAAAATAA

Upstream 100 bases:

>100_bases
AAATCAATAAAAATAAAATACTAAATAATATATAATTATAATTAATTTAAAAATATAAAAGATATAATATAAATAAAATT
ATTAATAAAAAGGTGATTTT

Downstream 100 bases:

>100_bases
ATATTTAGTGTATGAGGAACAAAAATGTTTGGAAAAGTTGAAGAAAAATTAAATAATGTATTAAAAACAGAGGGAGCTCT
CTATTTTATACTCATAGACC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: DHQ synthase

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVVIDKGDDLTILFDAKKEGKET
GVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLENLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYV
PKDINDVKDFATLIEKMNSEKLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATR
PFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIEAEYVGGEIVRTIVQNAETIR
LVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETIIEK

Sequences:

>Translated_362_residues
MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVVIDKGDDLTILFDAKKEGKET
GVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLENLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYV
PKDINDVKDFATLIEKMNSEKLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATR
PFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIEAEYVGGEIVRTIVQNAETIR
LVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETIIEK
>Mature_362_residues
MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVVIDKGDDLTILFDAKKEGKET
GVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLENLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYV
PKDINDVKDFATLIEKMNSEKLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATR
PFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIEAEYVGGEIVRTIVQNAETIR
LVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETIIEK

Specific function: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis

COG id: COG1465

COG function: function code E; Predicted alternative 3-dehydroquinate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type DHQ synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHQS_META3 (A6UW69)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325353.1
- STRING:   A6UW69
- GeneID:   5327715
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1164
- eggNOG:   arNOG05006
- HOGENOM:   HBG670179
- OMA:   DRVCIDT
- ProtClustDB:   PRK02290
- BioCyc:   MAEO419665:MAEO_1164-MONOMER
- HAMAP:   MF_01244
- InterPro:   IPR002812
- PIRSF:   PIRSF006655
- ProDom:   PD017907

Pfam domain/function: PF01959 DHQS

EC number: NA

Molecular weight: Translated: 40532; Mature: 40532

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVV
CCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCEEEECCCCCCCEEE
IDKGDDLTILFDAKKEGKETGVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLE
EECCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCEEEHH
NLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYVPKDINDVKDFATLIEKMNSE
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCC
KLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATR
CEECCHHHEEEEEECCCCCEEEEECHHHHHCCCCEEEECCCEEEEEEEECCCCCCEEEEC
PFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIE
CEEECCCCEEEEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEE
AEYVGGEIVRTIVQNAETIRLVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETII
EHHCCHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHH
EK
CC
>Mature Secondary Structure
MKFGWIMANDEDWEERKETVKDSLESSIPAVMVYEEDIEKVKELGNIKTISKNPNSDIVV
CCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCEEEECCCCCCCEEE
IDKGDDLTILFDAKKEGKETGVFISIECKEDEEYASEVSRYDYVDYIILEGKDWNIIPLE
EECCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCEEEHH
NLIADLFDENIKIVSLAKDINDARTAYEILERGVDGVLYVPKDINDVKDFATLIEKMNSE
HHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCC
KLDLDCATITKVEAIGSGDRVCIDTCSMMEMGEGMLIGSYSRALFLVHAETVENPYVATR
CEECCHHHEEEEEECCCCCEEEEECHHHHHCCCCEEEECCCEEEEEEEECCCCCCEEEEC
PFRVNAGPVHAYVLCTGNKTRYLSELKAGDGILIVDKDGMTREGIVGRVKIEKRPLMLIE
CEEECCCCEEEEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEE
AEYVGGEIVRTIVQNAETIRLVNENGAPISVVDLKVGDKVKLKIDTNARHFGMAIQETII
EHHCCHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHH
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA