| Definition | Staphylococcus aureus subsp. aureus JH1, complete genome. |
|---|---|
| Accession | NC_009632 |
| Length | 2,906,507 |
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The map label for this gene is hysA [H]
Identifier: 150394711
GI number: 150394711
Start: 2373266
End: 2375695
Strand: Direct
Name: hysA [H]
Synonym: SaurJH1_2271
Alternate gene names: 150394711
Gene position: 2373266-2375695 (Clockwise)
Preceding gene: 150394707
Following gene: 150394714
Centisome position: 81.65
GC content: 33.17
Gene sequence:
>2430_bases ATGACATATAGAATGAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG TGAATTCAGAAGTATTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAGTTGAGGA ACACATGGTTAGATGTTAACTACGGTTATGATAAGTATGATGAGAAGAATGACGCAATGAAGAAGAAGTTTGATGCTACG GAGAAAGAGGCAGAGAAATTACTCAGTAGCATGAAAACTGAAAGTGGAAGGACTTACTTGTGGGATAGTGCAAAAGATTT AGATAACAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAGGCATCCTAAAACCA CTTTAAATACTGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA GATAATAAAGTAAAAGAATTGACTGAGAATTTTAAAATAACTGATTCATCAAAGAAAAAAGCTTTAAATTGGTGGGATTA TGAAATTGGAACACCTAGATCATTAACAAATACGCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAAAAT TCACTGCCCCTATTAAAACTTTCGCCCCAAAAAGTGATGAAATATTATCTTCTGTAGGAAAAGCTGAACCTGCTAAAGGC GGAAATTTAGTAGACATTGCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATAAAGATATGATGAAAAATTCAAT AGATTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGATAAAGAACGTAATGGATTTTATAAAGATGGTT CATATATCGACCATAAAGATGTCCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCG ATGATAAAAGAAACACCTTTTAATGATAAAACCCAAAATAATACAACCTTAAAATCATGGATTGACGACGGATTTTTACC ACTCATTTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCCATTAGCCGTGAAAATGAAACGAGTCACTCAGCAT CTGCAACTGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAAAAAATTGTC AAAACTTCAGTTAAATCTGATTCAAGTTACGGCCAAAATGATACATTAAGCTCTTATTCGGATATAAGCAAAATGAAGTC TTTAATGGAAGACAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCT ATCACAATAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGA GAGAACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTT CTGGGCGACAGCTGATATGAAACGTTTAGCAGGTACAACAACTTTAGAAAATGAAGAACCTAAAGGTACGGATGTTAAAA AGTCGAGTAAAACTTTTGTAGGCGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGAC AAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGA TTCATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAA CCGCTTCCGATAATCAGGGAACCAATTCCGTCTTTTTAGAGTCAACCAATAAACCTAAAAACAATATAGGCTATCATTTT TTAAACGAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGTCAAAAGCAAGA CAGTAAAACTAATCAATATTATGAAGTAACTCAAAAGCATTCTAATACAGATAGTAAATATGCATATGTGTTGTATCCAG GCTTATCTAAAGATGACTTTAATACAAAAAAAGATAAAGTAACTGTCGTTAAACAAGATGATGACTTCCACGTTGTGAAA GATAATGAATCGGTTTGGGCTGGTGTTAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGAAGT TAAAGCCAAAGGAATGTTTATTCTTAAAAACAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAA ATACCGCTTCAGATATTGAATCTAAAATTTCAATAACTGGATACTCTATTACAAACAAAAATACATCAACTTCTAATGAA TCCGGCGTACACTTTGAATTAACTAAATAA
Upstream 100 bases:
>100_bases TAGACAGTCATTTGTATACGTTAACGAATTTTGAAAATTTGAATCATTATTTAATCATATTATTAATTGCGCACGCACAA CATAAAAAGGAGACATGTCA
Downstream 100 bases:
>100_bases GCAAGAAAATCTCGACACTATACCATTTTTATAGTGTCGAGATTTTATAAGTATCGCCATCATTCACCTTGTAATCCGCA GACCACATCCCCTTTGATAA
Product: polysaccharide lyase family protein 8
Products: NA
Alternate protein names: Hyaluronidase; HYase [H]
Number of amino acids: Translated: 809; Mature: 808
Protein sequence:
>809_residues MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFDAT EKEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRNIEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEP DNKVKELTENFKITDSSKKKALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKG GNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMP MIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIV KTSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQD KTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHF LNESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVK DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIESKISITGYSITNKNTSTSNE SGVHFELTK
Sequences:
>Translated_809_residues MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFDAT EKEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRNIEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEP DNKVKELTENFKITDSSKKKALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKG GNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMP MIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIV KTSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQD KTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHF LNESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVK DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIESKISITGYSITNKNTSTSNE SGVHFELTK >Mature_808_residues TYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFDATE KEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRNIEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEPD NKVKELTENFKITDSSKKKALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKGG NLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMPM IKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIVK TSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESINGE NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDK TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHFL NESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVKD NESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIESKISITGYSITNKNTSTSNES GVHFELTK
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the polysaccharide lyase 8 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008929 - InterPro: IPR011013 - InterPro: IPR014718 - InterPro: IPR011071 - InterPro: IPR012970 - InterPro: IPR004103 - InterPro: IPR003159 - InterPro: IPR012329 [H]
Pfam domain/function: PF02278 Lyase_8; PF02884 Lyase_8_C; PF08124 Lyase_8_N [H]
EC number: =4.2.2.1 [H]
Molecular weight: Translated: 91813; Mature: 91682
Theoretical pI: Translated: 8.45; Mature: 8.45
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVN CCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHCEEEEC YGYDKYDEKNDAMKKKFDATEKEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRN CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHH IEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEPDNKVKELTENFKITDSSKKK HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEECCCCCCC ALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKG CCCEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCC GNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKD CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC VPYTGAYGVVLLEGISQMMPMIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRG CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEECCEEECCCC RAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIVKTSVKSDSSYGQNDTLSSYS CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH DISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING HHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHEECCCCCCEEEECCCCCCCHHHHHCCCC ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFV CCCCCEECCCCCCEEECCCHHHHHHCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE GGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRK CCCCCCCCCCEECCCCCCCCCEEEECCEEEEEECEEEEEECCCCCCCCCCCCCEEECCCC ANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHFLNESKITVKKESHTGKWSDI CCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCCC NKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVK CCHHHHCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEE DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIE CCCCEEEECCCCCCCEEEECCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCHHHHH SKISITGYSITNKNTSTSNESGVHFELTK CEEEEEEEEEECCCCCCCCCCCEEEEECC >Mature Secondary Structure TYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVN CCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHCEEEEC YGYDKYDEKNDAMKKKFDATEKEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRN CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHH IEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEPDNKVKELTENFKITDSSKKK HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEECCCCCCC ALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKG CCCEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCC GNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKD CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC VPYTGAYGVVLLEGISQMMPMIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRG CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEECCEEECCCC RAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIVKTSVKSDSSYGQNDTLSSYS CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH DISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING HHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHEECCCCCCEEEECCCCCCCHHHHHCCCC ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFV CCCCCEECCCCCCEEECCCHHHHHHCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE GGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRK CCCCCCCCCCEECCCCCCCCCEEEECCEEEEEECEEEEEECCCCCCCCCCCCCEEECCCC ANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHFLNESKITVKKESHTGKWSDI CCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCCC NKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVK CCHHHHCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEE DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIE CCCCEEEECCCCCCCEEEECCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCHHHHH SKISITGYSITNKNTSTSNESGVHFELTK CEEEEEEEEEECCCCCCCCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7557301 [H]