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The map label for this gene is cirA [H]

Identifier: 150008079

GI number: 150008079

Start: 1677691

End: 1679997

Strand: Reverse

Name: cirA [H]

Synonym: BDI_1443

Alternate gene names: 150008079

Gene position: 1679997-1677691 (Counterclockwise)

Preceding gene: 150008080

Following gene: 150008070

Centisome position: 34.92

GC content: 52.19

Gene sequence:

>2307_bases
ATGAATAAGTTCATTACACTTATACTATGCCTGTGCTGTGTCTTTACATCAGCGTGGGCAGAGGGAGACGATCATACCTC
CCTGAATCCTTCCGACGCTAATATCGTAGGCCATATCCTCGATAAGAAAACAGGAGAGCATCTCTCTTTTATCAATGTCT
ACCTCCACGGTACGACGATCGGTACGACCACCGACGCTACCGGTCATTACTATATGAAGAATCTTCCCGAGGGAAAATAC
ACCTTGGTCATGAAGTCTATCGGATATAAAACCGAGGAGAAGACGGTGACCCTTAAGAAAGGGAAGACATTGGAGATCAA
TTTCAATGCCGAGGAAGACGCTGTCTCCTTGGACGGTGTCGTCGTATCGGCAAACCGTAACGAGACGACCCGCCGTCTGG
CTCCTTCTTTGGTAAATGTACTCGACTCCAAGGTGTTCGAGACTACGCACGCCACTTCCTTGGCCGACGGTCTGAACTTC
CAGCCCGGCGTGCGTGTGGAGAATAACTGCCAGAATTGCGGTTTCCAACAAGTACGTATCAATGGTCTGGAAGGCCCTTA
TACCCAGATCTTGGTGGATAGCCGGCCGATCTTCAGCGCCCTGACCGGCGTATATGGCTTGGAGCAGATCCCGGCGAATA
TGATCGAGCGGGTAGAGGTGATGCGCGGAGGAGGCTCGGCCTTGTTCGGCTCGTCCGCTATCGCCGGTACGATCAATATC
ATCACGAAGGAACCGATGCGCAACTCTGCCCAGATTGCCCATTCGTTGACGATGATCGGGGGAAGCCGTCCGGATAATAA
TACGACCGTGAACGCCTCGTTGGTGACGGACGATCATAAGGCGGGTATCTACCTCTTTGGGCAGGGCCGCCACCGTGCCT
CTTACGACCATGATGGCGATGGCTACTCGGAGCTGGGTAAGCTGGAGGCGAAGACCCTCGGATTCCGTTCCTACTTGAAG
ACCAGCAATTATTCCAAGCTGACTTTCGAGTACCATAACATCAGCGAGTTCCGGCGAGGTGGTAATTTATTGGATCTTCC
GCCTCACGAGACGGATATCACCGAGCAGACCGACCACCAGATCAACGGGGGAGGCCTGAAATTCGATCTTTTCTCTCGCG
ACTACCATCATCGGCTGAATGTGTATACCTCCGCCCAGCATACGAAACGCCAGAGTTATTACGGTGCCGGAAAAGATCCG
AACGCCTATGGTAACACGACGGACATGACCTTTATCGGTGGCGCCCAATATTCCTACGAATGGGATAAATGCCTTTTTAT
GCCCGCTACCTTTACGGGAGGCGCCGAATATAGCTACGATGATCTGCAAGACGAGATGCTTGGCTATCACCGTACGATCG
CCCAGACCGTGCATATCGGTAGCGCTTTCGCCCAGAACGAGTGGAAGAATGACCGTTGGAGTTTCTTGATCGGTGGCCGT
TTGGATAAGCATAACATGATGGATCATGTGATCTTTAGCCCTCGTGCGAACGTGCGCTTCAATCCGACGAAGGATATCAA
CCTGCGTATGTCGTACTCCAGCGGTTTCCGGGCCCCTCAAGCGTTCGACGAGGATTTGCATATCACCGCCGTGGGGGGCG
ACGTGGCGATCATCCAGATTTCTCCGGACTTGAAGGAGGAGAATTCGCAGAGCGTGAGCGCTTCCGTGGATTTTTATCAT
CGCTTCGGCCCGGTTCAAGTGAATTTCTTAGTGGAAGGTTTCTATACGGATTTACGGAACGTGTTTATCTTGGAGGAGAT
CGGCCGTGACGAGGACAATAATCTGCTGATGGAACGCCGTAATGGAAAGGGTGCCCGTGTGATGGGTATCAATCTGGAGG
GTAAGATGGCCTATTCTTGGATGCAGATACAGGCGGGCGCTACTTTGCAACGGAGCCGCTACAAGGAGGCAGAGCAATGG
AGCGAGAACCCGAATATCACCCCGCAGAAGAAGATGTTCCGCTCTCCGGACGTATATGGCTATTTCACCTCTACCTTCAC
GCCCGTGAAACGTTTCTCCGCCTCATTGACGGGAACCTATACGGGCAGCATGTTGGTGCAGCACTTGGCGGGTTACATTC
CCGAGGATCGTGAGGAGAAGACTCGTGATTTCTTCGACTTGAACCTGAAGCTGTCTTACGACTTCCCGATCTTCAAGTCC
GCAACCTTGCAGGTGAACGCCGGAATACAGAATATCTTCGACTCCTATCAAGATGATTTCGACAAGGGAGCGCATCGGGA
TGCCGGGTATATCTATGGCCCGGGAATTCCTAGAAGTTATTTCGTGGGGTGCAAGATCAGTTATTAA

Upstream 100 bases:

>100_bases
ATTACATATCCAGAAATCAATATCCGTTTGTAGAGACGGGGCATGCCCGTCTCCTCGGCAATTCGTAATCATTAATATTC
AAACAACTATTAATCAAGCA

Downstream 100 bases:

>100_bases
ATACTCGGCGAGCCTTGCCGAGGGAGTTGGAAGGACTTTGAAGCATCCGGCGGCTATCGCCGGGGGATGTGGAAGACTCT
TGGGATGCCCGGCGGGGGTC

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKTGEHLSFINVYLHGTTIGTTTDATGHYYMKNLPEGKY
TLVMKSIGYKTEEKTVTLKKGKTLEINFNAEEDAVSLDGVVVSANRNETTRRLAPSLVNVLDSKVFETTHATSLADGLNF
QPGVRVENNCQNCGFQQVRINGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINI
ITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVTDDHKAGIYLFGQGRHRASYDHDGDGYSELGKLEAKTLGFRSYLK
TSNYSKLTFEYHNISEFRRGGNLLDLPPHETDITEQTDHQINGGGLKFDLFSRDYHHRLNVYTSAQHTKRQSYYGAGKDP
NAYGNTTDMTFIGGAQYSYEWDKCLFMPATFTGGAEYSYDDLQDEMLGYHRTIAQTVHIGSAFAQNEWKNDRWSFLIGGR
LDKHNMMDHVIFSPRANVRFNPTKDINLRMSYSSGFRAPQAFDEDLHITAVGGDVAIIQISPDLKEENSQSVSASVDFYH
RFGPVQVNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERRNGKGARVMGINLEGKMAYSWMQIQAGATLQRSRYKEAEQW
SENPNITPQKKMFRSPDVYGYFTSTFTPVKRFSASLTGTYTGSMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKS
ATLQVNAGIQNIFDSYQDDFDKGAHRDAGYIYGPGIPRSYFVGCKISY

Sequences:

>Translated_768_residues
MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKTGEHLSFINVYLHGTTIGTTTDATGHYYMKNLPEGKY
TLVMKSIGYKTEEKTVTLKKGKTLEINFNAEEDAVSLDGVVVSANRNETTRRLAPSLVNVLDSKVFETTHATSLADGLNF
QPGVRVENNCQNCGFQQVRINGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINI
ITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVTDDHKAGIYLFGQGRHRASYDHDGDGYSELGKLEAKTLGFRSYLK
TSNYSKLTFEYHNISEFRRGGNLLDLPPHETDITEQTDHQINGGGLKFDLFSRDYHHRLNVYTSAQHTKRQSYYGAGKDP
NAYGNTTDMTFIGGAQYSYEWDKCLFMPATFTGGAEYSYDDLQDEMLGYHRTIAQTVHIGSAFAQNEWKNDRWSFLIGGR
LDKHNMMDHVIFSPRANVRFNPTKDINLRMSYSSGFRAPQAFDEDLHITAVGGDVAIIQISPDLKEENSQSVSASVDFYH
RFGPVQVNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERRNGKGARVMGINLEGKMAYSWMQIQAGATLQRSRYKEAEQW
SENPNITPQKKMFRSPDVYGYFTSTFTPVKRFSASLTGTYTGSMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKS
ATLQVNAGIQNIFDSYQDDFDKGAHRDAGYIYGPGIPRSYFVGCKISY
>Mature_768_residues
MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKTGEHLSFINVYLHGTTIGTTTDATGHYYMKNLPEGKY
TLVMKSIGYKTEEKTVTLKKGKTLEINFNAEEDAVSLDGVVVSANRNETTRRLAPSLVNVLDSKVFETTHATSLADGLNF
QPGVRVENNCQNCGFQQVRINGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINI
ITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVTDDHKAGIYLFGQGRHRASYDHDGDGYSELGKLEAKTLGFRSYLK
TSNYSKLTFEYHNISEFRRGGNLLDLPPHETDITEQTDHQINGGGLKFDLFSRDYHHRLNVYTSAQHTKRQSYYGAGKDP
NAYGNTTDMTFIGGAQYSYEWDKCLFMPATFTGGAEYSYDDLQDEMLGYHRTIAQTVHIGSAFAQNEWKNDRWSFLIGGR
LDKHNMMDHVIFSPRANVRFNPTKDINLRMSYSSGFRAPQAFDEDLHITAVGGDVAIIQISPDLKEENSQSVSASVDFYH
RFGPVQVNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERRNGKGARVMGINLEGKMAYSWMQIQAGATLQRSRYKEAEQW
SENPNITPQKKMFRSPDVYGYFTSTFTPVKRFSASLTGTYTGSMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKS
ATLQVNAGIQNIFDSYQDDFDKGAHRDAGYIYGPGIPRSYFVGCKISY

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=458, Percent_Identity=26.8558951965066, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790405, Length=141, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86092; Mature: 86092

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKTGEHLSFINVYLHGTTI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEHHCCCCCCCEEEEEEEEEEEEE
GTTTDATGHYYMKNLPEGKYTLVMKSIGYKTEEKTVTLKKGKTLEINFNAEEDAVSLDGV
CCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEEECCE
VVSANRNETTRRLAPSLVNVLDSKVFETTHATSLADGLNFQPGVRVENNCQNCGFQQVRI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
NGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINI
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEE
ITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVTDDHKAGIYLFGQGRHRASYDHDGD
EECCCCCCHHHHHHHHEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCC
GYSELGKLEAKTLGFRSYLKTSNYSKLTFEYHNISEFRRGGNLLDLPPHETDITEQTDHQ
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCCEEECCCCCCCCCCCCCCE
INGGGLKFDLFSRDYHHRLNVYTSAQHTKRQSYYGAGKDPNAYGNTTDMTFIGGAQYSYE
ECCCCEEEEEECCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCC
WDKCLFMPATFTGGAEYSYDDLQDEMLGYHRTIAQTVHIGSAFAQNEWKNDRWSFLIGGR
CCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCC
LDKHNMMDHVIFSPRANVRFNPTKDINLRMSYSSGFRAPQAFDEDLHITAVGGDVAIIQI
CCCCCCCHHEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEE
SPDLKEENSQSVSASVDFYHRFGPVQVNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERR
CCCCCCCCCCCEEEEEEHHCCCCCEEEEEEEEHHHHHHHHEEEEHHHCCCCCCCEEEEEC
NGKGARVMGINLEGKMAYSWMQIQAGATLQRSRYKEAEQWSENPNITPQKKMFRSPDVYG
CCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEE
YFTSTFTPVKRFSASLTGTYTGSMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKS
EECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEECCCCEEC
ATLQVNAGIQNIFDSYQDDFDKGAHRDAGYIYGPGIPRSYFVGCKISY
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKTGEHLSFINVYLHGTTI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEHHCCCCCCCEEEEEEEEEEEEE
GTTTDATGHYYMKNLPEGKYTLVMKSIGYKTEEKTVTLKKGKTLEINFNAEEDAVSLDGV
CCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEEECCE
VVSANRNETTRRLAPSLVNVLDSKVFETTHATSLADGLNFQPGVRVENNCQNCGFQQVRI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
NGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINI
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEE
ITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVTDDHKAGIYLFGQGRHRASYDHDGD
EECCCCCCHHHHHHHHEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCC
GYSELGKLEAKTLGFRSYLKTSNYSKLTFEYHNISEFRRGGNLLDLPPHETDITEQTDHQ
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCCEEECCCCCCCCCCCCCCE
INGGGLKFDLFSRDYHHRLNVYTSAQHTKRQSYYGAGKDPNAYGNTTDMTFIGGAQYSYE
ECCCCEEEEEECCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCC
WDKCLFMPATFTGGAEYSYDDLQDEMLGYHRTIAQTVHIGSAFAQNEWKNDRWSFLIGGR
CCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCC
LDKHNMMDHVIFSPRANVRFNPTKDINLRMSYSSGFRAPQAFDEDLHITAVGGDVAIIQI
CCCCCCCHHEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEE
SPDLKEENSQSVSASVDFYHRFGPVQVNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERR
CCCCCCCCCCCEEEEEEHHCCCCCEEEEEEEEHHHHHHHHEEEEHHHCCCCCCCEEEEEC
NGKGARVMGINLEGKMAYSWMQIQAGATLQRSRYKEAEQWSENPNITPQKKMFRSPDVYG
CCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEE
YFTSTFTPVKRFSASLTGTYTGSMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKS
EECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEECCCCEEC
ATLQVNAGIQNIFDSYQDDFDKGAHRDAGYIYGPGIPRSYFVGCKISY
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]