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The map label for this gene is mtaP [H]

Identifier: 150006138

GI number: 150006138

Start: 4516697

End: 4517575

Strand: Direct

Name: mtaP [H]

Synonym: BVU_3649

Alternate gene names: 150006138

Gene position: 4516697-4517575 (Clockwise)

Preceding gene: 150006137

Following gene: 150006139

Centisome position: 87.48

GC content: 41.3

Gene sequence:

>879_bases
ATGAAAAAATATTATGCAGAATCTGAGTTGATTATCAATCCCGACGGCTCTATCTTCCACCTTCATATCAAACCTGAACA
GTTGGCAAATAAAATAATTCTAGTAGGTGACCCCGGGCGTGTAGCATTAGTAGCTTCTCATTTCGATACTAAAGAATGTG
AAATAGAAAGCCGTGAGTTCAAGACCATTACCGGTACTTATAAAGGAAAACGTCTCACCGTAGTTTCCACCGGTATAGGT
TGTGACAATATAGACATTGTGATGAATGAATTAGATGCTTTGGCCAATATTGATTTCAATACCCGTTATGAAAAAGACCA
CTTGCGCCAATTGGAATTAGTACGTATCGGTACATGTGGCGGATTACAGCCTTATACTCCTGTTGGTACCTATGTTTGTT
CTGAAAAGTCTATCGGTTTTGACGGACTGCTTAATTTCTACGCCGGACGCAATGAGGTTTGCGATCTGAAATTAGAACAA
GCTTTTATAGATTACATGGGGTGGGAAGGTAATGTATGCATCGCCCACCCATACGTTATTGATGCCGACCGGGAATTAAT
AGACCGCATTGCGCAAAATGATATGGTCCGTGGCGTAACTATCGCCGCAGGAGGTTTTTTTGGTCCGCAAGGACGAGAAC
TCCGTATCCCATTGGCCGATCCTAAACAGAATGAAAAGATTGAGAAATTTGAATACAATGACTATCGCATCACTAACTTT
GAAATGGAAAGTTCCGCCCTTGCCGGATTAGCACGCCTGATGGGACACAAAGCCATGACTGTATGTATGGTGATTGCCAA
CCGACTAATAAAGGAAGCCAATACCGGCTATAAAAACTCTATTGATGGTTTGATAGAAAAAGTCTTGGAAAGAATATAA

Upstream 100 bases:

>100_bases
GTAACATCTACATCTAGGAAATAATCTGTTTGCATACTCATTAAAAAGACAAGAAATATAACATTAATTATACTGGCCAT
TAACCACAAAAATAAAGATT

Downstream 100 bases:

>100_bases
TTCCCAATTTAGGTGTCTATATAATATGGATAAGATTCACCGGATCATCTATCAATACTTATTCTTATTATCATCCAGAA
GAAGATTGGCATAAACAGAT

Product: purine nucleoside phosphorylase II

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKKYYAESELIINPDGSIFHLHIKPEQLANKIILVGDPGRVALVASHFDTKECEIESREFKTITGTYKGKRLTVVSTGIG
CDNIDIVMNELDALANIDFNTRYEKDHLRQLELVRIGTCGGLQPYTPVGTYVCSEKSIGFDGLLNFYAGRNEVCDLKLEQ
AFIDYMGWEGNVCIAHPYVIDADRELIDRIAQNDMVRGVTIAAGGFFGPQGRELRIPLADPKQNEKIEKFEYNDYRITNF
EMESSALAGLARLMGHKAMTVCMVIANRLIKEANTGYKNSIDGLIEKVLERI

Sequences:

>Translated_292_residues
MKKYYAESELIINPDGSIFHLHIKPEQLANKIILVGDPGRVALVASHFDTKECEIESREFKTITGTYKGKRLTVVSTGIG
CDNIDIVMNELDALANIDFNTRYEKDHLRQLELVRIGTCGGLQPYTPVGTYVCSEKSIGFDGLLNFYAGRNEVCDLKLEQ
AFIDYMGWEGNVCIAHPYVIDADRELIDRIAQNDMVRGVTIAAGGFFGPQGRELRIPLADPKQNEKIEKFEYNDYRITNF
EMESSALAGLARLMGHKAMTVCMVIANRLIKEANTGYKNSIDGLIEKVLERI
>Mature_292_residues
MKKYYAESELIINPDGSIFHLHIKPEQLANKIILVGDPGRVALVASHFDTKECEIESREFKTITGTYKGKRLTVVSTGIG
CDNIDIVMNELDALANIDFNTRYEKDHLRQLELVRIGTCGGLQPYTPVGTYVCSEKSIGFDGLLNFYAGRNEVCDLKLEQ
AFIDYMGWEGNVCIAHPYVIDADRELIDRIAQNDMVRGVTIAAGGFFGPQGRELRIPLADPKQNEKIEKFEYNDYRITNF
EMESSALAGLARLMGHKAMTVCMVIANRLIKEANTGYKNSIDGLIEKVLERI

Specific function: Endowed with a broad substrate specificity, being able to phosphorolytically cleave inosine, guanosine, and adenosine with a better efficiency than MTA [H]

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 32766; Mature: 32766

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYYAESELIINPDGSIFHLHIKPEQLANKIILVGDPGRVALVASHFDTKECEIESREF
CCCEECCCEEEECCCCCEEEEEECHHHHHCEEEEEECCCCEEEEEECCCCCCCEECCCEE
KTITGTYKGKRLTVVSTGIGCDNIDIVMNELDALANIDFNTRYEKDHLRQLELVRIGTCG
EEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEEEECCC
GLQPYTPVGTYVCSEKSIGFDGLLNFYAGRNEVCDLKLEQAFIDYMGWEGNVCIAHPYVI
CCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCEEEECCEEE
DADRELIDRIAQNDMVRGVTIAAGGFFGPQGRELRIPLADPKQNEKIEKFEYNDYRITNF
ECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEE
EMESSALAGLARLMGHKAMTVCMVIANRLIKEANTGYKNSIDGLIEKVLERI
ECHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MKKYYAESELIINPDGSIFHLHIKPEQLANKIILVGDPGRVALVASHFDTKECEIESREF
CCCEECCCEEEECCCCCEEEEEECHHHHHCEEEEEECCCCEEEEEECCCCCCCEECCCEE
KTITGTYKGKRLTVVSTGIGCDNIDIVMNELDALANIDFNTRYEKDHLRQLELVRIGTCG
EEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEEEECCC
GLQPYTPVGTYVCSEKSIGFDGLLNFYAGRNEVCDLKLEQAFIDYMGWEGNVCIAHPYVI
CCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCEEEECCEEE
DADRELIDRIAQNDMVRGVTIAAGGFFGPQGRELRIPLADPKQNEKIEKFEYNDYRITNF
ECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEE
EMESSALAGLARLMGHKAMTVCMVIANRLIKEANTGYKNSIDGLIEKVLERI
ECHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 7929153 [H]