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The map label for this gene is resA [H]

Identifier: 150006053

GI number: 150006053

Start: 4411500

End: 4412591

Strand: Direct

Name: resA [H]

Synonym: BVU_3557

Alternate gene names: 150006053

Gene position: 4411500-4412591 (Clockwise)

Preceding gene: 150006047

Following gene: 150006070

Centisome position: 85.44

GC content: 40.02

Gene sequence:

>1092_bases
ATGAAAAAATTAGTTTATTTATTGGCTGCAGGAAGTATGGCTTTCGTTGCATGTCAGAATTCGCCTTCCTATAAGGTTAC
AGGTTCAGTAGAAGACATCACTGATGGCGACACGATCTATTTACAGGAATACGCAGGAGGAAACCTTGTAAAACTTGATT
CTGCTATTGTCAAAAGCGGAACTTTCGTATTCACCGGAAAACAAGATACGGCTGTAAACCGCTACATCACTTATATGAAA
GGAGACAAGCGTTACTTTACTGATCTTTTTCTTGAAAATGGAAATATTAATGTAACCTTAGGTAAGGAAAGCAAAGTTTC
AGGTACTCCTAATAACGACGCTTACCAAAAATTCAAAGATGGCTTCATGGCTTTAAGCAAGGAAATGAATGAAATGTACC
AAAAGGCTCAAAGCGACACTAGCTTGACAGAAGAACAGGTAGAAGCTATCATGGCTGAGATTGAAAAGAAAGACAGTGTA
GGCATGGATATGGTTTATCAAACAATTGAAGCCAATATCACCAATCCGGTCGGTGTATATCTTCTCCCTTCCTATGCAGG
CGCATTCGAACTCGACAAACAAAAAGCGTTGGTAGAAAAAATTCCCGCTGCATTAGTTAATGAACGTATCAACAAGTTGA
AAGCCCACATTGAAACTTCAGAGAAAACGGCTGTAGGTCAGAAATACATTGATTTCTCTATGCAGACCCCTGAAGGTAAA
ACTGTAAGCCTGTCTGATTTCGTCAGCAAAAATAAATATACTTTGATTGACTTTTGGGCTAGCTGGTGCGGACCTTGCCG
TAAAGAAATGCCCAATGTTGTAGAAGCATACAAGGCTTTCAAAGATAAAGGCTTCGGAATTGTAGGTATTTCTTTAGACG
AGAATGCAGACAAGTGGAAAGAGGCTATCACTGCCTTGAATATTACATGGCCGCAAATGTCTGACCTGCAAGGTTGGAAC
AATGCAGGTGCAAAACTTTATGGTGTCAATTCAATTCCTGCTACCGTATTGGTTGATCAGGAAGGTACCATTGTTGCACG
TAATCTCCGTGGAGATGCCATCAAGTCCAAACTGAACGAACTATTGAAATAA

Upstream 100 bases:

>100_bases
AACTATAGATTCCTTATTTCATTCTGAAAATAAAAACCTTTTTTCCGCAAACATATTAATTAAGTAGTTATCTTTGCGTT
CAAATTATAATCATATTAAA

Downstream 100 bases:

>100_bases
AATAACTGCAAAATAGTTTACAAAGTAGGGATATTCAGTAAATGTCTCTAAAAAATAAGATGGCATATGAAGATGATAGG
GCATGACCATTTCATATGCC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKKLVYLLAAGSMAFVACQNSPSYKVTGSVEDITDGDTIYLQEYAGGNLVKLDSAIVKSGTFVFTGKQDTAVNRYITYMK
GDKRYFTDLFLENGNINVTLGKESKVSGTPNNDAYQKFKDGFMALSKEMNEMYQKAQSDTSLTEEQVEAIMAEIEKKDSV
GMDMVYQTIEANITNPVGVYLLPSYAGAFELDKQKALVEKIPAALVNERINKLKAHIETSEKTAVGQKYIDFSMQTPEGK
TVSLSDFVSKNKYTLIDFWASWCGPCRKEMPNVVEAYKAFKDKGFGIVGISLDENADKWKEAITALNITWPQMSDLQGWN
NAGAKLYGVNSIPATVLVDQEGTIVARNLRGDAIKSKLNELLK

Sequences:

>Translated_363_residues
MKKLVYLLAAGSMAFVACQNSPSYKVTGSVEDITDGDTIYLQEYAGGNLVKLDSAIVKSGTFVFTGKQDTAVNRYITYMK
GDKRYFTDLFLENGNINVTLGKESKVSGTPNNDAYQKFKDGFMALSKEMNEMYQKAQSDTSLTEEQVEAIMAEIEKKDSV
GMDMVYQTIEANITNPVGVYLLPSYAGAFELDKQKALVEKIPAALVNERINKLKAHIETSEKTAVGQKYIDFSMQTPEGK
TVSLSDFVSKNKYTLIDFWASWCGPCRKEMPNVVEAYKAFKDKGFGIVGISLDENADKWKEAITALNITWPQMSDLQGWN
NAGAKLYGVNSIPATVLVDQEGTIVARNLRGDAIKSKLNELLK
>Mature_363_residues
MKKLVYLLAAGSMAFVACQNSPSYKVTGSVEDITDGDTIYLQEYAGGNLVKLDSAIVKSGTFVFTGKQDTAVNRYITYMK
GDKRYFTDLFLENGNINVTLGKESKVSGTPNNDAYQKFKDGFMALSKEMNEMYQKAQSDTSLTEEQVEAIMAEIEKKDSV
GMDMVYQTIEANITNPVGVYLLPSYAGAFELDKQKALVEKIPAALVNERINKLKAHIETSEKTAVGQKYIDFSMQTPEGK
TVSLSDFVSKNKYTLIDFWASWCGPCRKEMPNVVEAYKAFKDKGFGIVGISLDENADKWKEAITALNITWPQMSDLQGWN
NAGAKLYGVNSIPATVLVDQEGTIVARNLRGDAIKSKLNELLK

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 40188; Mature: 40188

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVYLLAAGSMAFVACQNSPSYKVTGSVEDITDGDTIYLQEYAGGNLVKLDSAIVKSG
CCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEECHHHHCCC
TFVFTGKQDTAVNRYITYMKGDKRYFTDLFLENGNINVTLGKESKVSGTPNNDAYQKFKD
CEEEECCCCCHHHHEEEEEECCCCEEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
GFMALSKEMNEMYQKAQSDTSLTEEQVEAIMAEIEKKDSVGMDMVYQTIEANITNPVGVY
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEE
LLPSYAGAFELDKQKALVEKIPAALVNERINKLKAHIETSEKTAVGQKYIDFSMQTPEGK
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHEEEEEECCCCC
TVSLSDFVSKNKYTLIDFWASWCGPCRKEMPNVVEAYKAFKDKGFGIVGISLDENADKWK
EEEHHHHHCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
EAITALNITWPQMSDLQGWNNAGAKLYGVNSIPATVLVDQEGTIVARNLRGDAIKSKLNE
HHHHEEEECCCCCHHCCCCCCCCCEEEEECCCCEEEEECCCCCEEEECCCCHHHHHHHHH
LLK
HCC
>Mature Secondary Structure
MKKLVYLLAAGSMAFVACQNSPSYKVTGSVEDITDGDTIYLQEYAGGNLVKLDSAIVKSG
CCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEECHHHHCCC
TFVFTGKQDTAVNRYITYMKGDKRYFTDLFLENGNINVTLGKESKVSGTPNNDAYQKFKD
CEEEECCCCCHHHHEEEEEECCCCEEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
GFMALSKEMNEMYQKAQSDTSLTEEQVEAIMAEIEKKDSVGMDMVYQTIEANITNPVGVY
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEE
LLPSYAGAFELDKQKALVEKIPAALVNERINKLKAHIETSEKTAVGQKYIDFSMQTPEGK
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHEEEEEECCCCC
TVSLSDFVSKNKYTLIDFWASWCGPCRKEMPNVVEAYKAFKDKGFGIVGISLDENADKWK
EEEHHHHHCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
EAITALNITWPQMSDLQGWNNAGAKLYGVNSIPATVLVDQEGTIVARNLRGDAIKSKLNE
HHHHEEEECCCCCHHCCCCCCCCCEEEEECCCCEEEEECCCCCEEEECCCCHHHHHHHHH
LLK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA