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The map label for this gene is zraR [H]

Identifier: 150006029

GI number: 150006029

Start: 4383247

End: 4384578

Strand: Direct

Name: zraR [H]

Synonym: BVU_3527

Alternate gene names: 150006029

Gene position: 4383247-4384578 (Clockwise)

Preceding gene: 150006024

Following gene: 150006030

Centisome position: 84.89

GC content: 41.74

Gene sequence:

>1332_bases
ATGGAAAAAGGAACGATTTTAATAGTAGATGATAATAAAGGAGTATTGGCCTCACTGGAATTATTACTGGAAACGGAGTT
CAGCGAAATAAAGACAGCCCATCATCCGAATCAAATCATATCTATCATAAATACCTCTCCGATAGATGTGATTATTCTTG
ATATGAATTTCTCGGCAGGAATCAATAACGGCAACGAAGGGTTATATTGGCTGAAACGAATCCGTGAGATAGCTCCTGCA
CTACCAGTAGTCATGCTTACAGCATACGGGGATGTAGAACTGGCAGTAAAGGCTTTAAAGAATGATGCAACTGATTTTTT
GTTGAAACCTTGGGATAACCGGACCTTAGTGCGCAAAATAAAAGATGCTTTTGGAAGCGGTAAGAAAAGGAAAAACAGAA
TCCCCGATAGAAACAAATCACCGATGATTGTGGGAACATCACCTGCCATGCAGCAGTTAATGAAGATAGTAGTGAAAGTG
GCACGCACAGATGCCAATATATTGATTACCGGAGAAAACGGAACAGGAAAAGAAATGCTGGCACAGGAAATACACCGGTT
TTCCACACGAAAGGAACATTCTATGGTAACGGTAGATATGGGAGCAATCAGTGAATCTTTATTCGAAAGTGAACTGTTCG
GGCATGAGCGCGGTTCTTTTACCGATGCCTACGAGAGCCGGCCGGGAAAGTTTGAAGCGGCATCCGGCAGTTCCCTGTTT
ATGGATGAAATAGGAAATCTCCCTTTAGCCATGCAGGCAAAGTTGCTCACCGTATTACAAAACCGAAAAATTACACGCAT
CGGCAGTAATAAAGTAATCCCAGTGGATATCCGGCTGCTTTCAGCTACCAACAAGAATATTCAGGATATGGTGGATTCCG
GGACTTTCCGTGAGGATTTATTGTACAGACTGAATACTATTCATCTGGAAATCCCGCCTTTACGCGAACGGAGGGAAGAT
ATACATTTGTTCATTGATTATTTTATGCAGCGCTATGCTGCTAAATACGAAAAAAAAGAAATCTTCCTGCATGAACATGC
TTTAGAGAAATTATGTTCTTATCATTGGCCGGGAAATATCCGGGAATTGCAACATACCATCGAGAAAGCAGTTATTTTAT
GTGAAGGAGATGTAATCCGTTCCAAAGACATTTTCGTAAAACAAACCTGGAGTCCACAATTCTCCACTACCGTTCCTAAT
CTGGAAGAAGTAGAACGCCAGGCCATAGAAACAGCCATCCGTCAAAACGATGGAAATCTGACAGCAACAGCCGAACAGTT
AGGCATCAGCCGCCAGACACTTTACAATAAAATAAAACGCTTTAAGCTCTGA

Upstream 100 bases:

>100_bases
AAGCATTACAGAAAATAATAAAAAACGTCCAATAATTGGACGCCTCATTTGCAGAAACAATCAAAAGCAGATACCTTTAG
CCTCTGAAAGCAAAAATGAG

Downstream 100 bases:

>100_bases
TGATCATGGTATTCAGCAAACATCTATATATGGTTATCCTAAGCTACATCTTATTAATAATTGCTGTAGCCGGAGCTGGT
ATCGCACTTATTATTACACA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MEKGTILIVDDNKGVLASLELLLETEFSEIKTAHHPNQIISIINTSPIDVIILDMNFSAGINNGNEGLYWLKRIREIAPA
LPVVMLTAYGDVELAVKALKNDATDFLLKPWDNRTLVRKIKDAFGSGKKRKNRIPDRNKSPMIVGTSPAMQQLMKIVVKV
ARTDANILITGENGTGKEMLAQEIHRFSTRKEHSMVTVDMGAISESLFESELFGHERGSFTDAYESRPGKFEAASGSSLF
MDEIGNLPLAMQAKLLTVLQNRKITRIGSNKVIPVDIRLLSATNKNIQDMVDSGTFREDLLYRLNTIHLEIPPLRERRED
IHLFIDYFMQRYAAKYEKKEIFLHEHALEKLCSYHWPGNIRELQHTIEKAVILCEGDVIRSKDIFVKQTWSPQFSTTVPN
LEEVERQAIETAIRQNDGNLTATAEQLGISRQTLYNKIKRFKL

Sequences:

>Translated_443_residues
MEKGTILIVDDNKGVLASLELLLETEFSEIKTAHHPNQIISIINTSPIDVIILDMNFSAGINNGNEGLYWLKRIREIAPA
LPVVMLTAYGDVELAVKALKNDATDFLLKPWDNRTLVRKIKDAFGSGKKRKNRIPDRNKSPMIVGTSPAMQQLMKIVVKV
ARTDANILITGENGTGKEMLAQEIHRFSTRKEHSMVTVDMGAISESLFESELFGHERGSFTDAYESRPGKFEAASGSSLF
MDEIGNLPLAMQAKLLTVLQNRKITRIGSNKVIPVDIRLLSATNKNIQDMVDSGTFREDLLYRLNTIHLEIPPLRERRED
IHLFIDYFMQRYAAKYEKKEIFLHEHALEKLCSYHWPGNIRELQHTIEKAVILCEGDVIRSKDIFVKQTWSPQFSTTVPN
LEEVERQAIETAIRQNDGNLTATAEQLGISRQTLYNKIKRFKL
>Mature_443_residues
MEKGTILIVDDNKGVLASLELLLETEFSEIKTAHHPNQIISIINTSPIDVIILDMNFSAGINNGNEGLYWLKRIREIAPA
LPVVMLTAYGDVELAVKALKNDATDFLLKPWDNRTLVRKIKDAFGSGKKRKNRIPDRNKSPMIVGTSPAMQQLMKIVVKV
ARTDANILITGENGTGKEMLAQEIHRFSTRKEHSMVTVDMGAISESLFESELFGHERGSFTDAYESRPGKFEAASGSSLF
MDEIGNLPLAMQAKLLTVLQNRKITRIGSNKVIPVDIRLLSATNKNIQDMVDSGTFREDLLYRLNTIHLEIPPLRERRED
IHLFIDYFMQRYAAKYEKKEIFLHEHALEKLCSYHWPGNIRELQHTIEKAVILCEGDVIRSKDIFVKQTWSPQFSTTVPN
LEEVERQAIETAIRQNDGNLTATAEQLGISRQTLYNKIKRFKL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=39.6355353075171, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1788550, Length=461, Percent_Identity=37.9609544468547, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=33.4038054968288, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1788905, Length=442, Percent_Identity=35.972850678733, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI87082117, Length=318, Percent_Identity=40.5660377358491, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789087, Length=304, Percent_Identity=42.4342105263158, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=40.0621118012422, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789233, Length=327, Percent_Identity=37.6146788990826, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=38.75, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=33.5423197492163, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=34.0909090909091, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081858, Length=301, Percent_Identity=29.2358803986711, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789828, Length=322, Percent_Identity=30.1242236024845, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50290; Mature: 50290

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKGTILIVDDNKGVLASLELLLETEFSEIKTAHHPNQIISIINTSPIDVIILDMNFSAG
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEEECCCCC
INNGNEGLYWLKRIREIAPALPVVMLTAYGDVELAVKALKNDATDFLLKPWDNRTLVRKI
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHEECCCCCHHHHHHH
KDAFGSGKKRKNRIPDRNKSPMIVGTSPAMQQLMKIVVKVARTDANILITGENGTGKEML
HHHHCCCCCHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
AQEIHRFSTRKEHSMVTVDMGAISESLFESELFGHERGSFTDAYESRPGKFEAASGSSLF
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEECCCCCEEE
MDEIGNLPLAMQAKLLTVLQNRKITRIGSNKVIPVDIRLLSATNKNIQDMVDSGTFREDL
HHHHCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEECCCCCHHHHHHCCCHHHHH
LYRLNTIHLEIPPLRERREDIHLFIDYFMQRYAAKYEKKEIFLHEHALEKLCSYHWPGNI
HHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RELQHTIEKAVILCEGDVIRSKDIFVKQTWSPQFSTTVPNLEEVERQAIETAIRQNDGNL
HHHHHHHHHHEEEECCCEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
TATAEQLGISRQTLYNKIKRFKL
EEEHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKGTILIVDDNKGVLASLELLLETEFSEIKTAHHPNQIISIINTSPIDVIILDMNFSAG
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEEECCCCC
INNGNEGLYWLKRIREIAPALPVVMLTAYGDVELAVKALKNDATDFLLKPWDNRTLVRKI
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHEECCCCCHHHHHHH
KDAFGSGKKRKNRIPDRNKSPMIVGTSPAMQQLMKIVVKVARTDANILITGENGTGKEML
HHHHCCCCCHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
AQEIHRFSTRKEHSMVTVDMGAISESLFESELFGHERGSFTDAYESRPGKFEAASGSSLF
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEECCCCCEEE
MDEIGNLPLAMQAKLLTVLQNRKITRIGSNKVIPVDIRLLSATNKNIQDMVDSGTFREDL
HHHHCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEECCCCCHHHHHHCCCHHHHH
LYRLNTIHLEIPPLRERREDIHLFIDYFMQRYAAKYEKKEIFLHEHALEKLCSYHWPGNI
HHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RELQHTIEKAVILCEGDVIRSKDIFVKQTWSPQFSTTVPNLEEVERQAIETAIRQNDGNL
HHHHHHHHHHEEEECCCEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
TATAEQLGISRQTLYNKIKRFKL
EEEHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]