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The map label for this gene is aslA [H]

Identifier: 150005499

GI number: 150005499

Start: 3779408

End: 3780955

Strand: Reverse

Name: aslA [H]

Synonym: BVU_2983

Alternate gene names: 150005499

Gene position: 3780955-3779408 (Counterclockwise)

Preceding gene: 150005518

Following gene: 150005497

Centisome position: 73.23

GC content: 43.41

Gene sequence:

>1548_bases
ATGAAAAAAAGACATTACGGAATGCTTTCATTGGCACTTACTTCATGCTTGGCTGTTCATGCGGAAAACAAAAATCAAAA
TACAGACAAGCCCAATGTTATCTTCATCTATGCTGATGATTTAGGATATGGTGACTTGGAGTGTTATGGAGCAAAAAACG
TACAAACTCCAAATGTCAACCGTCTGGCATCCGAAGGGATACGATTTATCAACGCACACGCTACCGCCGCTACCAGTACC
CCATCCAGATATTCCATGCTGACCGGAGAATATGCATGGCGTAAACCCGGAACAGATGTAGCTGCCGGCAATGCAGGAAT
GATTATACGTCCCGAGCAATATACTATGGCAGATATGTTTAAAAGCTCCGGCTATGCCACAGGAGCATTTGGCAAATGGC
ATTTAGGATTAGGTGATAAAACTGCACAACAAGACTGGAATGCTCCTCTCTCTGCTTCTCTAGGTGATTTGGGGTTTGAC
TATTCCTATATCATGGCAGCCACAGCCGACCGGGTTCCCTGTGTATTTATCGAGAATGGCCAAGTAGCCAATTATGATCC
TTCAGCTCCGATAGAAGTAAGCTATATAAAAAATTTCCCCGGTGAACCTACCGGAAAAGACAACCCTGAACTTTTATATA
ATCTGAAACCGAGTCACGGTCATGATATGTCTATCGTGAACGGTATCAGCCGAATCGGTTATATGAAAGGAGGTGGCAAA
GCATTATGGAAAGATGAAAATATAGCCGATTCCATTACCGCACATGCAGTTGATTTTATCAAACAACATAAAGACGAGCC
TTTCTTTATGTATTTCGCCACTAATGATGTGCACGTTCCCCGTTTTCCACACAATCGTTTCCGTGGTAAAAACAAGATGG
GACTGCGCGGTGATGCTATCGCACAATTTGACTGGAGTGTAGGTCAGTTACTCGAAGCCCTCGATAAAATGGGATTAACC
CAGAACACATTAATTATTCTTTCCAGCGACAATGGACCGGTAGTAGACGACGGATATGATGACAAGGCAGAAGAGTTACT
GAACGGGCACGAACCTGCCGGCAACCTGAGAGGTGGAAAATACAGTGCATTTGAAGGGGGGACTCGTGTTCCTGTAATTG
TACACTGGCCTAAAGCCATCAACAAGCCGGAAGTCAGCGATGTGCTTATTTCGCAAATAGACTGGCTGGCATCACTAGCT
TCTCTGGTAGATGCCCGTATTCCGAAAGGAAGTGCTCCCGACAGCTACAACCGATTAGCAAATCTATTAGGACAAGACAA
AACAGACCGCCCATGGGTTATTGAACAGGCATCCAATCACACCCTATCCGTGCGTACTAAAGATTGGAAATTTATTGAAG
GCAGCGATGGTCCTAAAATGATTCCATGGGGTCCGAAAATTGAAACTGGTTATTTAGGTATTCCCCAGTTATATGATATG
AAACAAGCAGGTGAAAAGGTGAATTTAGCGACTGAACATCCCGAAAAAGTATTCGAATTACAACAAATATTGAGAAAAGT
ACGAGATAAAAGTATTCAGATGAAGTAA

Upstream 100 bases:

>100_bases
TACCACAATTTCATTCCACAATTTTGTAGAATTAATCCCCGTTTTTAAAATATATCTTTATCTTTGTAGAATTGATTACT
CACTAAACAATATAATTACT

Downstream 100 bases:

>100_bases
CATGCTGAATACACACCAACCCAATATTTCCAAAAGGGTGAATCAAGACAAAAGAATCACATAAAGGGTCTTGAATTCAC
CCTCTTTTTTAATCAAGAAA

Product: putative arylsulfatase precursor

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKKRHYGMLSLALTSCLAVHAENKNQNTDKPNVIFIYADDLGYGDLECYGAKNVQTPNVNRLASEGIRFINAHATAATST
PSRYSMLTGEYAWRKPGTDVAAGNAGMIIRPEQYTMADMFKSSGYATGAFGKWHLGLGDKTAQQDWNAPLSASLGDLGFD
YSYIMAATADRVPCVFIENGQVANYDPSAPIEVSYIKNFPGEPTGKDNPELLYNLKPSHGHDMSIVNGISRIGYMKGGGK
ALWKDENIADSITAHAVDFIKQHKDEPFFMYFATNDVHVPRFPHNRFRGKNKMGLRGDAIAQFDWSVGQLLEALDKMGLT
QNTLIILSSDNGPVVDDGYDDKAEELLNGHEPAGNLRGGKYSAFEGGTRVPVIVHWPKAINKPEVSDVLISQIDWLASLA
SLVDARIPKGSAPDSYNRLANLLGQDKTDRPWVIEQASNHTLSVRTKDWKFIEGSDGPKMIPWGPKIETGYLGIPQLYDM
KQAGEKVNLATEHPEKVFELQQILRKVRDKSIQMK

Sequences:

>Translated_515_residues
MKKRHYGMLSLALTSCLAVHAENKNQNTDKPNVIFIYADDLGYGDLECYGAKNVQTPNVNRLASEGIRFINAHATAATST
PSRYSMLTGEYAWRKPGTDVAAGNAGMIIRPEQYTMADMFKSSGYATGAFGKWHLGLGDKTAQQDWNAPLSASLGDLGFD
YSYIMAATADRVPCVFIENGQVANYDPSAPIEVSYIKNFPGEPTGKDNPELLYNLKPSHGHDMSIVNGISRIGYMKGGGK
ALWKDENIADSITAHAVDFIKQHKDEPFFMYFATNDVHVPRFPHNRFRGKNKMGLRGDAIAQFDWSVGQLLEALDKMGLT
QNTLIILSSDNGPVVDDGYDDKAEELLNGHEPAGNLRGGKYSAFEGGTRVPVIVHWPKAINKPEVSDVLISQIDWLASLA
SLVDARIPKGSAPDSYNRLANLLGQDKTDRPWVIEQASNHTLSVRTKDWKFIEGSDGPKMIPWGPKIETGYLGIPQLYDM
KQAGEKVNLATEHPEKVFELQQILRKVRDKSIQMK
>Mature_515_residues
MKKRHYGMLSLALTSCLAVHAENKNQNTDKPNVIFIYADDLGYGDLECYGAKNVQTPNVNRLASEGIRFINAHATAATST
PSRYSMLTGEYAWRKPGTDVAAGNAGMIIRPEQYTMADMFKSSGYATGAFGKWHLGLGDKTAQQDWNAPLSASLGDLGFD
YSYIMAATADRVPCVFIENGQVANYDPSAPIEVSYIKNFPGEPTGKDNPELLYNLKPSHGHDMSIVNGISRIGYMKGGGK
ALWKDENIADSITAHAVDFIKQHKDEPFFMYFATNDVHVPRFPHNRFRGKNKMGLRGDAIAQFDWSVGQLLEALDKMGLT
QNTLIILSSDNGPVVDDGYDDKAEELLNGHEPAGNLRGGKYSAFEGGTRVPVIVHWPKAINKPEVSDVLISQIDWLASLA
SLVDARIPKGSAPDSYNRLANLLGQDKTDRPWVIEQASNHTLSVRTKDWKFIEGSDGPKMIPWGPKIETGYLGIPQLYDM
KQAGEKVNLATEHPEKVFELQQILRKVRDKSIQMK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI146229331, Length=438, Percent_Identity=30.8219178082192, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI146229329, Length=438, Percent_Identity=30.8219178082192, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI6005990, Length=438, Percent_Identity=30.8219178082192, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI146229324, Length=438, Percent_Identity=30.8219178082192, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI53831991, Length=535, Percent_Identity=26.7289719626168, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI71852584, Length=467, Percent_Identity=29.1220556745182, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI58743319, Length=450, Percent_Identity=28.8888888888889, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4503899, Length=411, Percent_Identity=28.4671532846715, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI157266309, Length=540, Percent_Identity=26.4814814814815, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI71852586, Length=323, Percent_Identity=31.2693498452012, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI45430057, Length=426, Percent_Identity=27.4647887323944, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI146229327, Length=370, Percent_Identity=28.1081081081081, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI31742482, Length=169, Percent_Identity=34.9112426035503, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557659, Length=143, Percent_Identity=39.1608391608392, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI5360208, Length=143, Percent_Identity=40.5594405594406, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI109389362, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI59797060, Length=117, Percent_Identity=35.042735042735, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI38569405, Length=120, Percent_Identity=32.5, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI38569407, Length=120, Percent_Identity=32.5, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790233, Length=430, Percent_Identity=26.2790697674419, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081924, Length=541, Percent_Identity=24.9537892791128, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790112, Length=408, Percent_Identity=23.2843137254902, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533416, Length=453, Percent_Identity=26.2693156732892, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=276, Percent_Identity=29.3478260869565, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533418, Length=443, Percent_Identity=25.2821670428894, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366397, Length=528, Percent_Identity=25.1893939393939, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281366395, Length=528, Percent_Identity=25.1893939393939, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24666163, Length=528, Percent_Identity=25.1893939393939, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24666175, Length=164, Percent_Identity=29.8780487804878, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24666109, Length=117, Percent_Identity=34.1880341880342, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363223, Length=121, Percent_Identity=34.7107438016529, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 56929; Mature: 56929

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRHYGMLSLALTSCLAVHAENKNQNTDKPNVIFIYADDLGYGDLECYGAKNVQTPNVN
CCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHH
RLASEGIRFINAHATAATSTPSRYSMLTGEYAWRKPGTDVAAGNAGMIIRPEQYTMADMF
HHHHHCCEEEECCCEECCCCCCHHEEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
KSSGYATGAFGKWHLGLGDKTAQQDWNAPLSASLGDLGFDYSYIMAATADRVPCVFIENG
HCCCCEECCCCEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEEECC
QVANYDPSAPIEVSYIKNFPGEPTGKDNPELLYNLKPSHGHDMSIVNGISRIGYMKGGGK
EECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCEECCCCC
ALWKDENIADSITAHAVDFIKQHKDEPFFMYFATNDVHVPRFPHNRFRGKNKMGLRGDAI
EEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHCCCCCCCCCCCEE
AQFDWSVGQLLEALDKMGLTQNTLIILSSDNGPVVDDGYDDKAEELLNGHEPAGNLRGGK
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCE
YSAFEGGTRVPVIVHWPKAINKPEVSDVLISQIDWLASLASLVDARIPKGSAPDSYNRLA
EEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NLLGQDKTDRPWVIEQASNHTLSVRTKDWKFIEGSDGPKMIPWGPKIETGYLGIPQLYDM
HHHCCCCCCCCEEEEECCCCEEEEEECCEEEEECCCCCEECCCCCCCCCCCCCCCHHHHH
KQAGEKVNLATEHPEKVFELQQILRKVRDKSIQMK
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKRHYGMLSLALTSCLAVHAENKNQNTDKPNVIFIYADDLGYGDLECYGAKNVQTPNVN
CCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHH
RLASEGIRFINAHATAATSTPSRYSMLTGEYAWRKPGTDVAAGNAGMIIRPEQYTMADMF
HHHHHCCEEEECCCEECCCCCCHHEEEECCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
KSSGYATGAFGKWHLGLGDKTAQQDWNAPLSASLGDLGFDYSYIMAATADRVPCVFIENG
HCCCCEECCCCEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEEECC
QVANYDPSAPIEVSYIKNFPGEPTGKDNPELLYNLKPSHGHDMSIVNGISRIGYMKGGGK
EECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCEECCCCC
ALWKDENIADSITAHAVDFIKQHKDEPFFMYFATNDVHVPRFPHNRFRGKNKMGLRGDAI
EEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHCCCCCCCCCCCEE
AQFDWSVGQLLEALDKMGLTQNTLIILSSDNGPVVDDGYDDKAEELLNGHEPAGNLRGGK
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCE
YSAFEGGTRVPVIVHWPKAINKPEVSDVLISQIDWLASLASLVDARIPKGSAPDSYNRLA
EEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NLLGQDKTDRPWVIEQASNHTLSVRTKDWKFIEGSDGPKMIPWGPKIETGYLGIPQLYDM
HHHCCCCCCCCEEEEECCCCEEEEEECCEEEEECCCCCEECCCCCCCCCCCCCCCHHHHH
KQAGEKVNLATEHPEKVFELQQILRKVRDKSIQMK
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]