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The map label for this gene is cvrA [H]

Identifier: 150005271

GI number: 150005271

Start: 3499483

End: 3500931

Strand: Reverse

Name: cvrA [H]

Synonym: BVU_2743

Alternate gene names: 150005271

Gene position: 3500931-3499483 (Counterclockwise)

Preceding gene: 150005272

Following gene: 150005269

Centisome position: 67.81

GC content: 46.38

Gene sequence:

>1449_bases
ATGATATTTAATGCAGAAAACATTCTCTTGATAGGTTCCATCCTATTATTCGTAAGTATTGTAGTGAGTAAGACCGGATA
CCGGTTCGGAATCCCTACGTTACTTGTTTTTTTATTGGTCGGCATGCTATTCGGAAGCGATGGTCTGGGACTCCAGTTCC
ATGATGCGGGCGAAGCCCAGTTCATCGGCATGATGGCCCTTAGCATCATTCTGTTCTCAGGGGGTATGGATACCAAATAC
TCGGATATCAAACCTGTATTGCCACAAGGCATACTGCTTTCCACCTTCGGTGTGTTGCTTACTACTATTTTCACCGGATT
CTTTATTTATTGGATTTCCGGATTCTCGAATGTCAGCATTACCATGTCCCTGATGACGGCCATGCTGCTGGCGGCTACCA
TGTCCTCTACGGACTCTGCTTCCGTGTTCAACATCCTGCGCTCGCAAAGCATGAATCTGAAACATAACCTCCGACCGATG
CTGGAACTGGAAAGCGGAAGTAATGACCCTATGGCGTATATGCTTACTATCGTCCTGATACAGTTCATCACGTCGGCAGG
CATGGGGGCAGACGATATTCTGATTTCATTCCTGATTCAGTTTGCTGTGGGTGGCACATCAGGATTCCTGCTGGGAAAAC
TGGCGGTAGCAATCATCAACAAGATTGACTTGAAGAACCAGTCACTCTATCCTATCTTGCTGCTGAGCTTTATTTTCTTC
ACATTCACCATGACCGACCTGTGTAAAGGAAACGGCTATCTGGCTGTCTATATAGCAGGGATGATGGTGGGTAACGCACG
CATTGTAAACCGTAAGGAGATCGCTACTTTTATGAGCGGCATGACCTGGCTCTTCCAAATTATCATGTTCCTGAGCCTGG
GATTGCTGGTGAATCCCCATGAAATGTTGTCCATCGCCATACCGGCAACCTTGATCGGCATTTTCATGATTGTCCTCGCC
CGCCCGCTCAGTGTCCTGCTCTGCCTCCTTCCCTTTAAAAAGATGAACATCAACTCACGGCTGTTTATTTCCTGGGTGGG
ATTGCGCGGAGCAGTACCTATCATATTCGCCACTTATCCGGTAGTGGCTGATGTGCCGGGATCTACTCAGATTTTCAATA
TCGTATTCTTCATTACCATATTGTCTTTAGTGGTTCAAGGAACGACCATTTCATGGATGGCCAAATTACTCCATCTGGAT
ACCCCACTGGAAAAAACAGGAAATGATTTCGGAGTAGAGATACCGGAGGAAATCAATACAGACCTCCGCGATATCGTACT
GACGGAAGAAATGCTGGCAAAAGGAAACAGACTAATGGATATGAACCTGCCTAAAGGTATGCTGGTGATGCTGATAAAAA
GAGGAAACGAGTTCATGATTCCCAATGGCTCTCTGCAACTGCACGCCGGTGACAAGCTGCTGATTATCTCGGAAAGCAAA
ACGAAATAA

Upstream 100 bases:

>100_bases
GTATCTGGCTCAGTATGCCTGTATCCGATCTGTTAGCGTTTATCACAGCCTGCCTGATGCTGGCACATCATATTAAAAAA
TTAAACAAGATCACAGAAGT

Downstream 100 bases:

>100_bases
AAAATTTGCCCATGTGCCCACGTGCTGCGCTATGGTCCCGCATGGCAATTGGCACATGGGCAAATTCGCACATTATTCAA
CTGAGCAACAGCATGATATT

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MIFNAENILLIGSILLFVSIVVSKTGYRFGIPTLLVFLLVGMLFGSDGLGLQFHDAGEAQFIGMMALSIILFSGGMDTKY
SDIKPVLPQGILLSTFGVLLTTIFTGFFIYWISGFSNVSITMSLMTAMLLAATMSSTDSASVFNILRSQSMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFITSAGMGADDILISFLIQFAVGGTSGFLLGKLAVAIINKIDLKNQSLYPILLLSFIFF
TFTMTDLCKGNGYLAVYIAGMMVGNARIVNRKEIATFMSGMTWLFQIIMFLSLGLLVNPHEMLSIAIPATLIGIFMIVLA
RPLSVLLCLLPFKKMNINSRLFISWVGLRGAVPIIFATYPVVADVPGSTQIFNIVFFITILSLVVQGTTISWMAKLLHLD
TPLEKTGNDFGVEIPEEINTDLRDIVLTEEMLAKGNRLMDMNLPKGMLVMLIKRGNEFMIPNGSLQLHAGDKLLIISESK
TK

Sequences:

>Translated_482_residues
MIFNAENILLIGSILLFVSIVVSKTGYRFGIPTLLVFLLVGMLFGSDGLGLQFHDAGEAQFIGMMALSIILFSGGMDTKY
SDIKPVLPQGILLSTFGVLLTTIFTGFFIYWISGFSNVSITMSLMTAMLLAATMSSTDSASVFNILRSQSMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFITSAGMGADDILISFLIQFAVGGTSGFLLGKLAVAIINKIDLKNQSLYPILLLSFIFF
TFTMTDLCKGNGYLAVYIAGMMVGNARIVNRKEIATFMSGMTWLFQIIMFLSLGLLVNPHEMLSIAIPATLIGIFMIVLA
RPLSVLLCLLPFKKMNINSRLFISWVGLRGAVPIIFATYPVVADVPGSTQIFNIVFFITILSLVVQGTTISWMAKLLHLD
TPLEKTGNDFGVEIPEEINTDLRDIVLTEEMLAKGNRLMDMNLPKGMLVMLIKRGNEFMIPNGSLQLHAGDKLLIISESK
TK
>Mature_482_residues
MIFNAENILLIGSILLFVSIVVSKTGYRFGIPTLLVFLLVGMLFGSDGLGLQFHDAGEAQFIGMMALSIILFSGGMDTKY
SDIKPVLPQGILLSTFGVLLTTIFTGFFIYWISGFSNVSITMSLMTAMLLAATMSSTDSASVFNILRSQSMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFITSAGMGADDILISFLIQFAVGGTSGFLLGKLAVAIINKIDLKNQSLYPILLLSFIFF
TFTMTDLCKGNGYLAVYIAGMMVGNARIVNRKEIATFMSGMTWLFQIIMFLSLGLLVNPHEMLSIAIPATLIGIFMIVLA
RPLSVLLCLLPFKKMNINSRLFISWVGLRGAVPIIFATYPVVADVPGSTQIFNIVFFITILSLVVQGTTISWMAKLLHLD
TPLEKTGNDFGVEIPEEINTDLRDIVLTEEMLAKGNRLMDMNLPKGMLVMLIKRGNEFMIPNGSLQLHAGDKLLIISESK
TK

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=481, Percent_Identity=39.7089397089397, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 52865; Mature: 52865

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFNAENILLIGSILLFVSIVVSKTGYRFGIPTLLVFLLVGMLFGSDGLGLQFHDAGEAQ
CEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
FIGMMALSIILFSGGMDTKYSDIKPVLPQGILLSTFGVLLTTIFTGFFIYWISGFSNVSI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TMSLMTAMLLAATMSSTDSASVFNILRSQSMNLKHNLRPMLELESGSNDPMAYMLTIVLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
QFITSAGMGADDILISFLIQFAVGGTSGFLLGKLAVAIINKIDLKNQSLYPILLLSFIFF
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TFTMTDLCKGNGYLAVYIAGMMVGNARIVNRKEIATFMSGMTWLFQIIMFLSLGLLVNPH
HHHHHHHHCCCCEEEEEEEHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCEECHH
EMLSIAIPATLIGIFMIVLARPLSVLLCLLPFKKMNINSRLFISWVGLRGAVPIIFATYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCEEEEECC
VVADVPGSTQIFNIVFFITILSLVVQGTTISWMAKLLHLDTPLEKTGNDFGVEIPEEINT
EEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHCC
DLRDIVLTEEMLAKGNRLMDMNLPKGMLVMLIKRGNEFMIPNGSLQLHAGDKLLIISESK
CHHHHHHHHHHHHCCCEEEECCCCCHHHHHEEECCCEEECCCCCEEEECCCEEEEEECCC
TK
CC
>Mature Secondary Structure
MIFNAENILLIGSILLFVSIVVSKTGYRFGIPTLLVFLLVGMLFGSDGLGLQFHDAGEAQ
CEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
FIGMMALSIILFSGGMDTKYSDIKPVLPQGILLSTFGVLLTTIFTGFFIYWISGFSNVSI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TMSLMTAMLLAATMSSTDSASVFNILRSQSMNLKHNLRPMLELESGSNDPMAYMLTIVLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
QFITSAGMGADDILISFLIQFAVGGTSGFLLGKLAVAIINKIDLKNQSLYPILLLSFIFF
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TFTMTDLCKGNGYLAVYIAGMMVGNARIVNRKEIATFMSGMTWLFQIIMFLSLGLLVNPH
HHHHHHHHCCCCEEEEEEEHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCEECHH
EMLSIAIPATLIGIFMIVLARPLSVLLCLLPFKKMNINSRLFISWVGLRGAVPIIFATYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCEEEEECC
VVADVPGSTQIFNIVFFITILSLVVQGTTISWMAKLLHLDTPLEKTGNDFGVEIPEEINT
EEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHCC
DLRDIVLTEEMLAKGNRLMDMNLPKGMLVMLIKRGNEFMIPNGSLQLHAGDKLLIISESK
CHHHHHHHHHHHHCCCEEEECCCCCHHHHHEEECCCEEECCCCCEEEECCCEEEEEECCC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA