Click here to switch to the map view.

The map label for this gene is mepA [H]

Identifier: 150005272

GI number: 150005272

Start: 3500928

End: 3502280

Strand: Reverse

Name: mepA [H]

Synonym: BVU_2744

Alternate gene names: 150005272

Gene position: 3502280-3500928 (Counterclockwise)

Preceding gene: 150005281

Following gene: 150005271

Centisome position: 67.83

GC content: 46.56

Gene sequence:

>1353_bases
ATGAAAGAAAACAACCCGCACATACTGGGTACAGAAAAGGTCGGAAAGCTGCTTTTAGAGTACTCTATCCCTGCCATCAT
AGGGATGACACTGACATCACTGTACAATATTATTGATAGTGTATTTATCGGCCATGGTGTCGGCGCCATGGCCATATCGG
GTTTGGCTATTTCTTTTCCGCTGATGAATCTGCTGGTGGCATTCTGTACACTGGTCGGGGTGGGTGGCGCTACCATTTCT
TCTATCCGCCTGGGGCAGAAGGATACGGACGGTGCCGAGAAGGTGCTGGGAAACGTAACGGTGCTCTGTGTGATAAATTC
TATTTTCTACGGAGGCATCACCCTGCTGTTTCTGGACCGGATTCTGTTCTTCTTCGGGGCAAGCCATGACACGTTGCCAT
ACGCCCGCGACTTTATGCAGATTATATTAATAGGAAGTCCTGTCACCTATGTAATGATCGGACTGAATAATATCATGCGT
GCCACCGGTTATCCCCGAAAGGCGATGCTGTCCTCCATGCTGACAGTGGGATGCAACATTATTCTGGCTCCTGTCTTTAT
TTTCTGGCTCGGTTGGGGAATCCGCGGAGCAGCCACGGCAACCATCCTTTCACAGTTTGCCGGCATGATATGGGTGCTGA
GCCATTTCATGCAGGAAAAAAGTTATATCCGCTTCAAGAAAGGGATATTCAAATTAAGGAAACGGATCGTAGAGAATATC
TTCAGTATAGGTATGTCGCCGTTCCTGATGAATGTCTGCGCTTCGGCCATTGTCATTATATTCAACAAGAGCCTGCTGCT
CTACGGGGGCGATCTGGCTATCGGCGCATACGGCATATTAAACCGTCTGCTGATGCTGTTTGTAATGGTTATCATGGGGC
TGACTATGGGAATGCAACCGATTGTGGGCTATAATCATGGCGCACACAAATTCGGCCGGGTGAAGCAGACTTTGAAATAT
TGCATGATTGCAGGGGGGTGCATCACTTCGTTGGGATTTGCTTTCAGCGAACTTTTCCCTAATTTGGTTGTTAATATGTT
TACAGACGATAAAGAACTTACAGCATTGGCACGCACCGGGTTACAAATCGGAGTACTGATGTTTCCTTTCGTGGGAATAC
AAATTGTAATTTCCAGTTTCTTCCAATCTATCGGGAAAGCGAAAATTTCTATCTTCCTCTCCTTGTCCCGCCAACTGTTG
TATTTATTACCCTGCCTGCTGTTACTACCTCATTGGTGGGGACTGAACGGTATCTGGCTCAGTATGCCTGTATCCGATCT
GTTAGCGTTTATCACAGCCTGCCTGATGCTGGCACATCATATTAAAAAATTAAACAAGATCACAGAAGTATGA

Upstream 100 bases:

>100_bases
GTTGAATTCATATTACTTTTAGTTTGATTTAACGCCACAAAGGTCCGAATAATCCTCCATATTCCTAACTTTGCAAAGCT
TAAAAATAACAAAAACGCGA

Downstream 100 bases:

>100_bases
TATTTAATGCAGAAAACATTCTCTTGATAGGTTCCATCCTATTATTCGTAAGTATTGTAGTGAGTAAGACCGGATACCGG
TTCGGAATCCCTACGTTACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKENNPHILGTEKVGKLLLEYSIPAIIGMTLTSLYNIIDSVFIGHGVGAMAISGLAISFPLMNLLVAFCTLVGVGGATIS
SIRLGQKDTDGAEKVLGNVTVLCVINSIFYGGITLLFLDRILFFFGASHDTLPYARDFMQIILIGSPVTYVMIGLNNIMR
ATGYPRKAMLSSMLTVGCNIILAPVFIFWLGWGIRGAATATILSQFAGMIWVLSHFMQEKSYIRFKKGIFKLRKRIVENI
FSIGMSPFLMNVCASAIVIIFNKSLLLYGGDLAIGAYGILNRLLMLFVMVIMGLTMGMQPIVGYNHGAHKFGRVKQTLKY
CMIAGGCITSLGFAFSELFPNLVVNMFTDDKELTALARTGLQIGVLMFPFVGIQIVISSFFQSIGKAKISIFLSLSRQLL
YLLPCLLLLPHWWGLNGIWLSMPVSDLLAFITACLMLAHHIKKLNKITEV

Sequences:

>Translated_450_residues
MKENNPHILGTEKVGKLLLEYSIPAIIGMTLTSLYNIIDSVFIGHGVGAMAISGLAISFPLMNLLVAFCTLVGVGGATIS
SIRLGQKDTDGAEKVLGNVTVLCVINSIFYGGITLLFLDRILFFFGASHDTLPYARDFMQIILIGSPVTYVMIGLNNIMR
ATGYPRKAMLSSMLTVGCNIILAPVFIFWLGWGIRGAATATILSQFAGMIWVLSHFMQEKSYIRFKKGIFKLRKRIVENI
FSIGMSPFLMNVCASAIVIIFNKSLLLYGGDLAIGAYGILNRLLMLFVMVIMGLTMGMQPIVGYNHGAHKFGRVKQTLKY
CMIAGGCITSLGFAFSELFPNLVVNMFTDDKELTALARTGLQIGVLMFPFVGIQIVISSFFQSIGKAKISIFLSLSRQLL
YLLPCLLLLPHWWGLNGIWLSMPVSDLLAFITACLMLAHHIKKLNKITEV
>Mature_450_residues
MKENNPHILGTEKVGKLLLEYSIPAIIGMTLTSLYNIIDSVFIGHGVGAMAISGLAISFPLMNLLVAFCTLVGVGGATIS
SIRLGQKDTDGAEKVLGNVTVLCVINSIFYGGITLLFLDRILFFFGASHDTLPYARDFMQIILIGSPVTYVMIGLNNIMR
ATGYPRKAMLSSMLTVGCNIILAPVFIFWLGWGIRGAATATILSQFAGMIWVLSHFMQEKSYIRFKKGIFKLRKRIVENI
FSIGMSPFLMNVCASAIVIIFNKSLLLYGGDLAIGAYGILNRLLMLFVMVIMGLTMGMQPIVGYNHGAHKFGRVKQTLKY
CMIAGGCITSLGFAFSELFPNLVVNMFTDDKELTALARTGLQIGVLMFPFVGIQIVISSFFQSIGKAKISIFLSLSRQLL
YLLPCLLLLPHWWGLNGIWLSMPVSDLLAFITACLMLAHHIKKLNKITEV

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49412; Mature: 49412

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENNPHILGTEKVGKLLLEYSIPAIIGMTLTSLYNIIDSVFIGHGVGAMAISGLAISFP
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LMNLLVAFCTLVGVGGATISSIRLGQKDTDGAEKVLGNVTVLCVINSIFYGGITLLFLDR
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFFFGASHDTLPYARDFMQIILIGSPVTYVMIGLNNIMRATGYPRKAMLSSMLTVGCNI
HHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILAPVFIFWLGWGIRGAATATILSQFAGMIWVLSHFMQEKSYIRFKKGIFKLRKRIVENI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIGMSPFLMNVCASAIVIIFNKSLLLYGGDLAIGAYGILNRLLMLFVMVIMGLTMGMQP
HHCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IVGYNHGAHKFGRVKQTLKYCMIAGGCITSLGFAFSELFPNLVVNMFTDDKELTALARTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
LQIGVLMFPFVGIQIVISSFFQSIGKAKISIFLSLSRQLLYLLPCLLLLPHWWGLNGIWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SMPVSDLLAFITACLMLAHHIKKLNKITEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA