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The map label for this gene is frdC [H]

Identifier: 148828019

GI number: 148828019

Start: 1412779

End: 1413189

Strand: Reverse

Name: frdC [H]

Synonym: CGSHiGG_07670

Alternate gene names: 148828019

Gene position: 1413189-1412779 (Counterclockwise)

Preceding gene: 148828020

Following gene: 148828018

Centisome position: 74.88

GC content: 36.5

Gene sequence:

>411_bases
ATGTCAGTAACAGTGAGTAAACGTAAAAAATATGTTCGTCCAATGACAGCGACTTGGTGGCAAAAATTGGACTTCTACAA
AGCTTATATGCTACGTGAAGCGACTTCAGTCTTTGCTGTATGGTTTTGTATTGTATTGCTTTATGGTGTTCTTTGTCTTG
CAAGCAATCCAATGCCAGGCTTAGGCATCTTGAGCTTTATTGAGTTTTTAAGAAACCCTATTGTGGTGTTCTTAAATATT
ATTACGCTTATCGCAACGCTTTATCATACGGTGACATATTTCTTAATGACACCAAAAGTGATGAATATCATTGTGAAAAA
TGAACGCTTACCACACACAGTTGTAAGAAATGCACTTTGGGCGGTAACCGCATTAGTTAGCGTGATTGCGTTAGTTTTAG
TTTATATTTAA

Upstream 100 bases:

>100_bases
AAACATGTGGATCCTGCTTCTGCAATTAACCAAGGAAAAGTGGAAAGTGCTAAAGATTATGTTATCTCTATGCTAAAACC
AAAAGGCTAAGGGGAAAGGA

Downstream 100 bases:

>100_bases
GGGAGAGAAAAAATGGTTGATCAAAATCCAAAACGCTCCGGCGAACCGCCAGTATGGTTAATGTTCGGTGCAGGCGGCAC
AGTGAGTGCAATTTTCCTTC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSVTVSKRKKYVRPMTATWWQKLDFYKAYMLREATSVFAVWFCIVLLYGVLCLASNPMPGLGILSFIEFLRNPIVVFLNI
ITLIATLYHTVTYFLMTPKVMNIIVKNERLPHTVVRNALWAVTALVSVIALVLVYI

Sequences:

>Translated_136_residues
MSVTVSKRKKYVRPMTATWWQKLDFYKAYMLREATSVFAVWFCIVLLYGVLCLASNPMPGLGILSFIEFLRNPIVVFLNI
ITLIATLYHTVTYFLMTPKVMNIIVKNERLPHTVVRNALWAVTALVSVIALVLVYI
>Mature_135_residues
SVTVSKRKKYVRPMTATWWQKLDFYKAYMLREATSVFAVWFCIVLLYGVLCLASNPMPGLGILSFIEFLRNPIVVFLNII
TLIATLYHTVTYFLMTPKVMNIIVKNERLPHTVVRNALWAVTALVSVIALVLVYI

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family [H]

Homologues:

Organism=Escherichia coli, GI1790595, Length=126, Percent_Identity=50, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003510
- ProDom:   PD015900 [H]

Pfam domain/function: PF02300 Fumarate_red_C [H]

EC number: 1.3.99.1

Molecular weight: Translated: 15617; Mature: 15486

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTVSKRKKYVRPMTATWWQKLDFYKAYMLREATSVFAVWFCIVLLYGVLCLASNPMPG
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGILSFIEFLRNPIVVFLNIITLIATLYHTVTYFLMTPKVMNIIVKNERLPHTVVRNALW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AVTALVSVIALVLVYI
HHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SVTVSKRKKYVRPMTATWWQKLDFYKAYMLREATSVFAVWFCIVLLYGVLCLASNPMPG
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGILSFIEFLRNPIVVFLNIITLIATLYHTVTYFLMTPKVMNIIVKNERLPHTVVRNALW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AVTALVSVIALVLVYI
HHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]