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The map label for this gene is frdB [H]

Identifier: 148828020

GI number: 148828020

Start: 1413214

End: 1413969

Strand: Reverse

Name: frdB [H]

Synonym: CGSHiGG_07675

Alternate gene names: 148828020

Gene position: 1413969-1413214 (Counterclockwise)

Preceding gene: 148828022

Following gene: 148828019

Centisome position: 74.92

GC content: 39.02

Gene sequence:

>756_bases
ATGGCTAATTCACCAGTAATGAATGTAGAAGTATTACGCTACAATCCTGAAATCGATCAAGAGCCACATTTAAGCACCTA
TCAAGTACCTTATGATAATCAAACTTCATTGCTTGATGCGTTAGGCTATATTAAGGATAAACTTGAACCATCTCTTTCTT
ATCGTTGGTCTTGCCGTATGGCGATCTGCGGTTCTTGCGGGATGATGGTAAATAACAAACCAAAATTGGCTTGTAAAACT
TTCTTACGTGATTACAGCGGCCATATGCGTATCGAGCCATTAGCAAACTTCCCTATTGAACGTGACTTAGTGGTTGATTT
AAGCCACTTTATCGAAAGTTTAGAGGCAATTAAGCCTTATATTATTGGTAACGAAGCACCAGCATTAGATGGTAAACCAC
ATCCATCGAAAGAATTACAAGTAAGCCGTACTAAACAAACACCAGCACAGCTTGAGAAATATCGTCAATTCTCAATGTGT
ATCAACTGTGGTTTATGCTATGCTGCTTGCCCTCAATTTGGTTTAAATCCTGAATTCTTAGGCCCTGCAGCTATTACAAT
GGCACACCGTTACAACCTTGATAACCGTGACCACGGTAAAGCAAAACGTATGTCATTATTAAATGGTAAAACGGGGTTTG
GAGTTGTACTTTCGTTGGCTATTGCTCAGAAGTTTGTCCAAAACATGTGGATCCTGCTTCTGCAATTAACCAAGGAAAAG
TGGAAAGTGCTAAAGATTATGTTATCTCTATGCTAA

Upstream 100 bases:

>100_bases
TACAGTCCGGTGAAAATTACTAAATCTCAACCTGCAAAACGTGTTTACGGTGCGGAAGCAGAAGCTCAAGAAGCAGCTGC
GAAAGCTAAGGAGCAAGCAA

Downstream 100 bases:

>100_bases
AACCAAAAGGCTAAGGGGAAAGGAATGTCAGTAACAGTGAGTAAACGTAAAAAATATGTTCGTCCAATGACAGCGACTTG
GTGGCAAAAATTGGACTTCT

Product: fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MANSPVMNVEVLRYNPEIDQEPHLSTYQVPYDNQTSLLDALGYIKDKLEPSLSYRWSCRMAICGSCGMMVNNKPKLACKT
FLRDYSGHMRIEPLANFPIERDLVVDLSHFIESLEAIKPYIIGNEAPALDGKPHPSKELQVSRTKQTPAQLEKYRQFSMC
INCGLCYAACPQFGLNPEFLGPAAITMAHRYNLDNRDHGKAKRMSLLNGKTGFGVVLSLAIAQKFVQNMWILLLQLTKEK
WKVLKIMLSLC

Sequences:

>Translated_251_residues
MANSPVMNVEVLRYNPEIDQEPHLSTYQVPYDNQTSLLDALGYIKDKLEPSLSYRWSCRMAICGSCGMMVNNKPKLACKT
FLRDYSGHMRIEPLANFPIERDLVVDLSHFIESLEAIKPYIIGNEAPALDGKPHPSKELQVSRTKQTPAQLEKYRQFSMC
INCGLCYAACPQFGLNPEFLGPAAITMAHRYNLDNRDHGKAKRMSLLNGKTGFGVVLSLAIAQKFVQNMWILLLQLTKEK
WKVLKIMLSLC
>Mature_250_residues
ANSPVMNVEVLRYNPEIDQEPHLSTYQVPYDNQTSLLDALGYIKDKLEPSLSYRWSCRMAICGSCGMMVNNKPKLACKTF
LRDYSGHMRIEPLANFPIERDLVVDLSHFIESLEAIKPYIIGNEAPALDGKPHPSKELQVSRTKQTPAQLEKYRQFSMCI
NCGLCYAACPQFGLNPEFLGPAAITMAHRYNLDNRDHGKAKRMSLLNGKTGFGVVLSLAIAQKFVQNMWILLLQLTKEKW
KVLKIMLSLC

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=211, Percent_Identity=31.7535545023697, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1790596, Length=212, Percent_Identity=70.2830188679245, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1786943, Length=208, Percent_Identity=37.9807692307692, Blast_Score=130, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=203, Percent_Identity=31.5270935960591, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322987, Length=204, Percent_Identity=35.2941176470588, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17137106, Length=207, Percent_Identity=32.8502415458937, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24643156, Length=201, Percent_Identity=31.3432835820896, Blast_Score=106, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28430; Mature: 28298

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSPVMNVEVLRYNPEIDQEPHLSTYQVPYDNQTSLLDALGYIKDKLEPSLSYRWSCRM
CCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
AICGSCGMMVNNKPKLACKTFLRDYSGHMRIEPLANFPIERDLVVDLSHFIESLEAIKPY
EEECCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCE
IIGNEAPALDGKPHPSKELQVSRTKQTPAQLEKYRQFSMCINCGLCYAACPQFGLNPEFL
EECCCCCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
GPAAITMAHRYNLDNRDHGKAKRMSLLNGKTGFGVVLSLAIAQKFVQNMWILLLQLTKEK
CHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKVLKIMLSLC
HHHHHHHHHHC
>Mature Secondary Structure 
ANSPVMNVEVLRYNPEIDQEPHLSTYQVPYDNQTSLLDALGYIKDKLEPSLSYRWSCRM
CCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
AICGSCGMMVNNKPKLACKTFLRDYSGHMRIEPLANFPIERDLVVDLSHFIESLEAIKPY
EEECCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCE
IIGNEAPALDGKPHPSKELQVSRTKQTPAQLEKYRQFSMCINCGLCYAACPQFGLNPEFL
EECCCCCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
GPAAITMAHRYNLDNRDHGKAKRMSLLNGKTGFGVVLSLAIAQKFVQNMWILLLQLTKEK
CHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKVLKIMLSLC
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]