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The map label for this gene is lpxH [H]

Identifier: 148827923

GI number: 148827923

Start: 1320512

End: 1321225

Strand: Direct

Name: lpxH [H]

Synonym: CGSHiGG_07140

Alternate gene names: 148827923

Gene position: 1320512-1321225 (Clockwise)

Preceding gene: 148827919

Following gene: 148827926

Centisome position: 69.97

GC content: 35.29

Gene sequence:

>714_bases
ATGAAACATAGCTATTTTATTTCTGATTTGCATTTAAGCGAAACTCAGCCAGAATTGACCGCACTTTTTGTCGATTTTAT
GCAGAATCTTGCCCCACAGGCTGAACGGCTTTACATTTTAGGTGATCTTTTTGATTTTTGGATTGGTGATGATGAGCAGT
CTACATTGATTCAACAAGTTAAAGATTTAATTAAGTCTGTAAGTAATCAAGGTGTGCAATGTTATTTTCAGCACGGTAAC
CGTGATTTCTTAATTGGTGAACGTTTTTCAAAAGAAACGGGAGCTCAGCTTTTACCTGATTATCAATTGATTACACTTTA
TGATAAAAAAATCTTACTTTGTCATGGCGATACGCTTTGTATTGATGACGTGGCTTATCAACAATTTCGCCGTAGAGTGC
ATCAAAAATGGCTGCAACGTTTGTTTTTGTGCTTGCCATTAAAAGTTCGGTTGAAAATTGCGGAGAAAATTCGAGCAAAG
AGTAATCAAGATAAACAAGCGAAATCACAGGAAATTATGGATATAAATCAAGCCTTCACGACAGAAAAAGTACAAGAATT
TGGTGTAAATTTATTAATTCACGGACACACACACCGTGAGGCGATTCATCAACAAGAAGGATTTACCCGAATTGTATTAG
GGGATTGGCGAAAAAATTACGCATCAATTTTAAAAATGGATGAAAGCGGAGAATTTGGTTTTATTAAAGATTAG

Upstream 100 bases:

>100_bases
AAGTAGTTTTAACATAAGGATGTCCTATATAAAATTTCGTTGAAGTATAGCAAATTCGATCTCAATATGTGCTAATCTAA
ACAAAAATCGTGGAATTTTT

Downstream 100 bases:

>100_bases
AAGTGCGGTAAAGCAAAAACTCGTTATTTTACTTAATGATACTAGAATAATACTTATCCATAAAATCGTACCTAAAAGCT
GGTGGATAAGCCCAACTTTT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSNQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAK
SNQDKQAKSQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD

Sequences:

>Translated_237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSNQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAK
SNQDKQAKSQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD
>Mature_237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSNQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAK
SNQDKQAKSQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=218, Percent_Identity=50.4587155963303, Blast_Score=236, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 27726; Mature: 27726

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQV
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHCCCCHHHHHHHHH
KDLIKSVSNQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLC
HHHHHHHHCCCEEEEEECCCEEEEECCHHCHHCCHHHCCCCEEEEEECCEEEEEECCEEE
IDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAKSNQDKQAKSQEIMDINQAFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD
HHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQV
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHCCCCHHHHHHHHH
KDLIKSVSNQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLC
HHHHHHHHCCCEEEEEECCCEEEEECCHHCHHCCHHHCCCCEEEEEECCEEEEEECCEEE
IDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAKSNQDKQAKSQEIMDINQAFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD
HHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA