Click here to switch to the map view.

The map label for this gene is nanE [H]

Identifier: 148827286

GI number: 148827286

Start: 617296

End: 617982

Strand: Reverse

Name: nanE [H]

Synonym: CGSHiGG_03315

Alternate gene names: 148827286

Gene position: 617982-617296 (Counterclockwise)

Preceding gene: 148827291

Following gene: 148827285

Centisome position: 32.75

GC content: 42.5

Gene sequence:

>687_bases
ATGTCTAAATTATCTTATCAAGAAGTGCTTTCTCAAATTCAATATGGTCTTATTTCTTCTTGCCAACCTGTCGATGATGG
CCCAATGGATAAACCTGAAATCGTTTCTGCTATGGCTCAGGCTTCGGTTATGGGCGGCGCTTCTGGCTTACGTATTGAGG
GTGTTGATAACCTTAAAGCAACCCGTCCTTTTGTGAATGTTCCGATTATCGGAATTGTAAAACGTGATTTGCCTGATAGT
CCCGTGCGTATTACGCCGTTTTTACAAGATATTGAAGATCTAGCCAATGCAGGCGCGGATATTATTGCAGTAGATGGCAC
TAAACGCCCACGTCCTGTGGATATTGAAAGTGCGGTGAAAAAAATCCACGAAATGGGCTGTTTGGCAATGGCAGATTGTT
CTAATTTAGAAGAAGGCTTGTATTGTAAAGCGCTTGGTTTTGATATTGTCGGCAGTACGATGTCGGGTTATACAGGTGGC
GCAGTGCCAGAAGAACCAGATTATCAATTAGTGAAAGATTTAAAATCAGCGGGTTGTTTTGTGATGGCTGAGGGGCGTTA
TAACACGCCAGAATTGGCAAAAGTGGCAATTGAAATTGGTGCAGATTGCGTGACTGTAGGTTCAGCCTTAACTCGTCTTG
AACATATTGTGAGTTGGTTTGCTAATTCAGTGAAATCTGCAAGATAG

Upstream 100 bases:

>100_bases
AATGATGAAAATATAAGCATATTACAACTTATAAAAGATTGTTTTATGTGGATTAAATTAATTTTAAAGTGATTTATTCA
GATTTAAATGAGGGTGTTAT

Downstream 100 bases:

>100_bases
TCGTAAGACGTGTGAGAAAAGACTTTACACTATAAGGATAAGTTATGCGTTGTTTAGCACTAGATATTGGTGGAACAAAA
ATTGCAGCGGCGATTGTAAA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTKRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

Sequences:

>Translated_228_residues
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTKRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
>Mature_227_residues
SKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDSP
VRITPFLQDIEDLANAGADIIAVDGTKRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGA
VPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=212, Percent_Identity=62.2641509433962, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24309; Mature: 24178

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHH
TRPFVNVPIIGIVKRDLPDSPVRITPFLQDIEDLANAGADIIAVDGTKRPRPVDIESAVK
CCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
KIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGAVPEEPDYQLVKDLKSAGCF
HHHHHCCHHHHHHCCCCCCCEEEHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEE
VMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHH
TRPFVNVPIIGIVKRDLPDSPVRITPFLQDIEDLANAGADIIAVDGTKRPRPVDIESAVK
CCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
KIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGAVPEEPDYQLVKDLKSAGCF
HHHHHCCHHHHHHCCCCCCCEEEHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEE
VMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]