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The map label for this gene is hflC

Identifier: 148827291

GI number: 148827291

Start: 623174

End: 624061

Strand: Reverse

Name: hflC

Synonym: CGSHiGG_03340

Alternate gene names: 148827291

Gene position: 624061-623174 (Counterclockwise)

Preceding gene: 148827292

Following gene: 148827286

Centisome position: 33.07

GC content: 38.18

Gene sequence:

>888_bases
ATGCGTAGATTTTTATTACCTGTTATTTTCGTGATTGCGGCAGTCGTTTATTCTAGTATCGTCGTTGTAACGGAAGGTAC
CCGTGGCATTATGTTACGATTTAACAAAGTACAGCGTGATGCTGATAACAAAGTGGTTGTATATGAACCAGGCTTGCATT
TTAAAGTGCCTTTAATTGATAGCATCAAAGTTTTAGATGCGCGTATTCGTACTTTAGATGGCTCTGCAACACGTTTTGTT
ACTGTTGAGAAAAAAGATTTGCTAGTGGATTCTTATGTGAAATGGAAAATCAGTGATTTTGGTCGATTCTACACATCTAC
TGGCGGTGGCGATTATGCTCAAGCTGCAAATTTATTAAGTCGTAAAGTAAACGACCGTTTACGTTCTGAAATTGGTTCAC
GCACGATTAAAGATATTGTTTCTGGTACACGTGGAGAATTAATGGAAGGGGCAAAAAAAGCTTTAAGTTCAGGACAAGAC
AGTACGGCAGAATTAGGTATTGAAGTGATCGATGTGCGTGTAAAACAAATTAATTTACCAGACGAAGTCTCTTCTTCGAT
TTACCAACGTATGCGTGCAGAACGTGATGCAGTGGCACGTGAACATCGTTCTCAAGGGAAAGAAAAAGCAGCATTTATTC
AAGCTGATGTAGATCGCAAAGTGACGTTAATTCTTGCTAATGCAAATAAAACTGCACAAGAATTACGAGGTTCAGGCGAT
GCAGCTGCAGCAAAATTATATTCAGATGCTTTTGCTCAAGAACCACAATTCTTTACTTTTGTGCGTAGCTTAAAAGCCTA
TGAAGCGAGTTTTGCAAATTCTGACAATATAATGATTTTAAAACCAGATAGTGATTTCTTCCGCTTTATGCAAGCACCGA
AAAAATAG

Upstream 100 bases:

>100_bases
CGGTCAATTCTTCGCCTGCTTTTACTGCACCAGAACGTCAAAATTCTTATCAGCCTCAGCCGACTACCGTTGCGCCGATT
CGTCAAGGGAGATTTAACTA

Downstream 100 bases:

>100_bases
AGTTTAATTTGATAAAAACACCTTCCTCGTGAAGGTGTTTTTTTTATAGCCAACGTCTTACTTTTTGTTTGTAACGACGA
TATTCATCGCCAAATTTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRRFLLPVIFVIAAVVYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLIDSIKVLDARIRTLDGSATRFV
TVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQD
STAELGIEVIDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGD
AAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQAPKK

Sequences:

>Translated_295_residues
MRRFLLPVIFVIAAVVYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLIDSIKVLDARIRTLDGSATRFV
TVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQD
STAELGIEVIDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGD
AAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQAPKK
>Mature_295_residues
MRRFLLPVIFVIAAVVYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLIDSIKVLDARIRTLDGSATRFV
TVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQD
STAELGIEVIDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGD
AAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQAPKK

Specific function: HflC and HflK could encode or regulate a protease

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily

Homologues:

Organism=Escherichia coli, GI1790617, Length=313, Percent_Identity=53.6741214057508, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFLC_HAEIN (P44545)

Other databases:

- EMBL:   L42023
- PIR:   I64050
- RefSeq:   NP_438320.1
- ProteinModelPortal:   P44545
- SMR:   P44545
- GeneID:   951060
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0150
- TIGR:   HI_0150
- HOGENOM:   HBG427952
- OMA:   RIKRIDL
- ProtClustDB:   CLSK869973
- BioCyc:   HINF71421:HI_0150-MONOMER
- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972
- PANTHER:   PTHR10264
- SMART:   SM00244
- TIGRFAMs:   TIGR01932

Pfam domain/function: PF01145 Band_7

EC number: 3.4.-.-

Molecular weight: Translated: 32902; Mature: 32902

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11a80484)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFLLPVIFVIAAVVYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLID
CCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEHHHHCCCCCEEEEECCCCEEECCCHH
SIKVLDARIRTLDGSATRFVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLS
HHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHEEEHHHHHHHHCCCCCCHHHHHHHHHH
RKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQDSTAELGIEVIDVRVKQINLP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCEEEEEEEEEECCCC
DEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEEEEECCCHHHHHHCCCCC
AAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQAPKK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCH
>Mature Secondary Structure
MRRFLLPVIFVIAAVVYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLID
CCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEHHHHCCCCCEEEEECCCCEEECCCHH
SIKVLDARIRTLDGSATRFVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLS
HHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHEEEHHHHHHHHCCCCCCHHHHHHHHHH
RKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQDSTAELGIEVIDVRVKQINLP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCEEEEEEEEEECCCC
DEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEEEEECCCHHHHHHCCCCC
AAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQAPKK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800