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The map label for this gene is nagA [H]

Identifier: 148827281

GI number: 148827281

Start: 612187

End: 613335

Strand: Reverse

Name: nagA [H]

Synonym: CGSHiGG_03280

Alternate gene names: 148827281

Gene position: 613335-612187 (Counterclockwise)

Preceding gene: 148827282

Following gene: 148827278

Centisome position: 32.5

GC content: 39.43

Gene sequence:

>1149_bases
ATGAAATACGCATTAACCAACAGTGTGATCTACACTAAATACGAAATTCTACGAGATTATGCGGTAGTAATTGATGGCGA
GACTATTGAAGCAGTAATCCCGCAAACTGAATTAGAAAAGGACATCAAAACCATTGATTTACAAGGTAATAATTTGACCG
CAGGTTTTATTGATCTGCAATTAAATGGCTGTGGTGGTGTGATGTTTAACGACCAAACTAGCGTTGAAACCTTGGAAATT
ATGCAGGAAACTAATTTAAAATCAGGTTGTACAAGTTTCCTTCCCACTTTTATTACTGCGCCTGATGAAAATATAAAAAG
TGCGGTGAAAATTATGCGTGAATATTTAAACAAGCATAAAAACCAAGCACTTGGTTTACATATTGAAGGGCCTTATCTCA
GCATTGAGAAAAAAGGCGTGCACCGTCCCGAATATATTCGTGAAATTACGCCAGAAATGAAAGATTTTCTCTGTGAAAAT
TCGGATGTCATTACAAAAATTACCATTGCCGCAGAAAATCCAACTATTAACTATACGCCCGATTTTGTGGAAGCGGGCAT
TATTGTCTCTGTAGGGCATTCCAACGCAAGCTATGAGGTGGCTAAAGCCGCATTCCATAAAGGTGCAACTTTTGCGACTC
ACTTACATAATGCAATGTCGCCAATTAGCTCTGGACGTGAAATGGGCGTAGTGGGTGCAGTATTAGATTCTGATGTTTAC
ACTGGCATAATCGTCGATGGTGTGCATATCAATTACGGCAATGTTCGCATTGATAAAAAAATCAAAGGCGACAAACTTTG
TATTGTGACTGACTCTATTGCAGCGGCAGGCGCACCGCCAGAACTAGAAAGTTTTACCTTTGAGGGAAAAACAATTTATA
TCAAAGAAGGGCGTTGCTATGATGCGAATGGCACCATTGCAGGGGCATCAATCACAATGATGGAATCTATTAAAAATGCG
GTAGAATATGTTGAAATTCCTCTTGCGGAAGCCATTAGAATGAGTAACCTTTATCCTGCACGAGCAATTGGTGTAGATGA
TCGTTTAGGTTCGGTAGAAAAAGGTAAGATAGCAAACTTAGCCGTGTTTACGCCAAATTACCAAGTAATCGGCACAGTAG
TAAACGGAAAGTGGAAAGAGAATGAATAG

Upstream 100 bases:

>100_bases
ACTGAATTAGAAGGTGCGGTTGCAGGGACTTATTACGGCGATAAATAACCTATCATTTTTACAATCAGTCGTTTTTCTTA
AAAAATTTGGAAGGTATAAA

Downstream 100 bases:

>100_bases
TAAACAGAAAGTGGAAAGAGAATTAATAGTAAACACTTAAATAGTTAATTGATTTAAAAATCTGTGATATATATCACAGA
TTTTTTATTAATATTTTGAC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKYALTNSVIYTKYEILRDYAVVIDGETIEAVIPQTELEKDIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCEN
SDVITKITIAAENPTINYTPDFVEAGIIVSVGHSNASYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDANGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGVDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKENE

Sequences:

>Translated_382_residues
MKYALTNSVIYTKYEILRDYAVVIDGETIEAVIPQTELEKDIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCEN
SDVITKITIAAENPTINYTPDFVEAGIIVSVGHSNASYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDANGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGVDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKENE
>Mature_382_residues
MKYALTNSVIYTKYEILRDYAVVIDGETIEAVIPQTELEKDIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCEN
SDVITKITIAAENPTINYTPDFVEAGIIVSVGHSNASYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDANGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGVDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKENE

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=429, Percent_Identity=27.5058275058275, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI224922791, Length=422, Percent_Identity=27.7251184834123, Blast_Score=141, Evalue=9e-34,
Organism=Escherichia coli, GI1786892, Length=378, Percent_Identity=55.026455026455, Blast_Score=425, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17553768, Length=357, Percent_Identity=32.4929971988796, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19920392, Length=389, Percent_Identity=30.5912596401028, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=30.0995024875622, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41785; Mature: 41785

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYALTNSVIYTKYEILRDYAVVIDGETIEAVIPQTELEKDIKTIDLQGNNLTAGFIDLQ
CCEEECCCEEEHHHHHHCCEEEEEECCEEEEECCHHHHHCCCEEEEECCCEEEEEEEEEE
LNGCGGVMFNDQTSVETLEIMQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHK
ECCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHCC
NQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCENSDVITKITIAAENPTINYTP
CCEEEEEECCCEEEEECCCCCCHHHHHHHCHHHHHHHCCCCCEEEEEEEEECCCEECCCC
DFVEAGIIVSVGHSNASYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
CHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCY
EEEEEEEEEEECCCEEEECCCCCCEEEEEECCHHCCCCCCCCCCEEECCEEEEEECCEEE
DANGTIAGASITMMESIKNAVEYVEIPLAEAIRMSNLYPARAIGVDDRLGSVEKGKIANL
CCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEE
AVFTPNYQVIGTVVNGKWKENE
EEECCCCEEEEEEECCEECCCC
>Mature Secondary Structure
MKYALTNSVIYTKYEILRDYAVVIDGETIEAVIPQTELEKDIKTIDLQGNNLTAGFIDLQ
CCEEECCCEEEHHHHHHCCEEEEEECCEEEEECCHHHHHCCCEEEEECCCEEEEEEEEEE
LNGCGGVMFNDQTSVETLEIMQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHK
ECCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHCC
NQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCENSDVITKITIAAENPTINYTP
CCEEEEEECCCEEEEECCCCCCHHHHHHHCHHHHHHHCCCCCEEEEEEEEECCCEECCCC
DFVEAGIIVSVGHSNASYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
CHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCY
EEEEEEEEEEECCCEEEECCCCCCEEEEEECCHHCCCCCCCCCCEEECCEEEEEECCEEE
DANGTIAGASITMMESIKNAVEYVEIPLAEAIRMSNLYPARAIGVDDRLGSVEKGKIANL
CCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEE
AVFTPNYQVIGTVVNGKWKENE
EEECCCCEEEEEEECCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]