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The map label for this gene is dnaQ [H]

Identifier: 148827278

GI number: 148827278

Start: 609241

End: 610011

Strand: Reverse

Name: dnaQ [H]

Synonym: CGSHiGG_03265

Alternate gene names: 148827278

Gene position: 610011-609241 (Counterclockwise)

Preceding gene: 148827281

Following gene: 148827277

Centisome position: 32.32

GC content: 36.58

Gene sequence:

>771_bases
ATGATTAATCCCAATCGCCAAATTGTATTAGATACTGAAACTACAGGTATGAATCAGCTCGGCGCGCATTATGAAGGACA
CTGCATTATTGAAATTGGTGCAGTTGAATTAATAAATCGTCGTTACACAGGTAATAATTTCCATATTTACATTAAGCCAG
ATCGCCCTGTTGATCCTGATGCGATTAAAGTTCATGGTATTACTGATGAAATGTTAGCGGATAAACCTGAATTCAAAGAC
GTTGCCCAAGATTTTTTGGATTATATTAATGGTGCGGAATTGCTTATTCACAATGCCCCCTTTGATGTTGGATTTATGGA
TTATGAATTTCGTAAACTTAACCTTAATGTGAAAACTGACGATATTTGTTTGGTAACAGATACGCTACAAATGGCGCGTC
AGATGTATCCTGGAAAACGCAGTAATTTGGATGCACTTTGTGAGCGTTTAGGTATTGATAATAGCAAACGTACTTTGCAC
GGTGCGTTACTGGATGCCGAGATCTTGGCGGATGTTTATTTGATGATGACGGGAGGGCAAACAAATTTATTCGATGAAGA
AGAATCTGTTGAGTCTGGAGTTATCCATGTTATGCAAGAAAAAACGGCGGAAGAAATAAAAAGTGCGGTAGATTTTTCGC
ACAATTTGAAATTACTTCAACCTACTAATGATGAGTTACAAGCGCATTTAGAATTCTTAAAGATGATGAATAAAAAAAGT
GGAAATAATTGCCTTTGGGATAAACGCTTTGGCAATAATAATGTGCATTAA

Upstream 100 bases:

>100_bases
AGCAAGATCCATCAGTAAAAATTTCAATCTGTTTTTGCATAACAAAAAGGTTGTTGTGTAGAATGGCAAGTATTTTAATG
GAAAGAGAGAGGTTGAACAA

Downstream 100 bases:

>100_bases
TCGTGTGGAATTTAAGCAGGTAAGTAAAATTTAATAAAAAAAGATTGACGAGATTTGTGTTCATCATTAAGATACGCACC
ACTTAGCGGAGTGGTAGTTC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MINPNRQIVLDTETTGMNQLGAHYEGHCIIEIGAVELINRRYTGNNFHIYIKPDRPVDPDAIKVHGITDEMLADKPEFKD
VAQDFLDYINGAELLIHNAPFDVGFMDYEFRKLNLNVKTDDICLVTDTLQMARQMYPGKRSNLDALCERLGIDNSKRTLH
GALLDAEILADVYLMMTGGQTNLFDEEESVESGVIHVMQEKTAEEIKSAVDFSHNLKLLQPTNDELQAHLEFLKMMNKKS
GNNCLWDKRFGNNNVH

Sequences:

>Translated_256_residues
MINPNRQIVLDTETTGMNQLGAHYEGHCIIEIGAVELINRRYTGNNFHIYIKPDRPVDPDAIKVHGITDEMLADKPEFKD
VAQDFLDYINGAELLIHNAPFDVGFMDYEFRKLNLNVKTDDICLVTDTLQMARQMYPGKRSNLDALCERLGIDNSKRTLH
GALLDAEILADVYLMMTGGQTNLFDEEESVESGVIHVMQEKTAEEIKSAVDFSHNLKLLQPTNDELQAHLEFLKMMNKKS
GNNCLWDKRFGNNNVH
>Mature_256_residues
MINPNRQIVLDTETTGMNQLGAHYEGHCIIEIGAVELINRRYTGNNFHIYIKPDRPVDPDAIKVHGITDEMLADKPEFKD
VAQDFLDYINGAELLIHNAPFDVGFMDYEFRKLNLNVKTDDICLVTDTLQMARQMYPGKRSNLDALCERLGIDNSKRTLH
GALLDAEILADVYLMMTGGQTNLFDEEESVESGVIHVMQEKTAEEIKSAVDFSHNLKLLQPTNDELQAHLEFLKMMNKKS
GNNCLWDKRFGNNNVH

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=243, Percent_Identity=59.6707818930041, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1788149, Length=181, Percent_Identity=32.0441988950276, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 29111; Mature: 29111

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINPNRQIVLDTETTGMNQLGAHYEGHCIIEIGAVELINRRYTGNNFHIYIKPDRPVDPD
CCCCCCEEEEECCCCCHHHHCCCCCCEEEEEECHHHHHHHEECCCEEEEEECCCCCCCCC
AIKVHGITDEMLADKPEFKDVAQDFLDYINGAELLIHNAPFDVGFMDYEFRKLNLNVKTD
CEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEECEEEEEEEEEECCC
DICLVTDTLQMARQMYPGKRSNLDALCERLGIDNSKRTLHGALLDAEILADVYLMMTGGQ
CEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCC
TNLFDEEESVESGVIHVMQEKTAEEIKSAVDFSHNLKLLQPTNDELQAHLEFLKMMNKKS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
GNNCLWDKRFGNNNVH
CCCCEEECCCCCCCCC
>Mature Secondary Structure
MINPNRQIVLDTETTGMNQLGAHYEGHCIIEIGAVELINRRYTGNNFHIYIKPDRPVDPD
CCCCCCEEEEECCCCCHHHHCCCCCCEEEEEECHHHHHHHEECCCEEEEEECCCCCCCCC
AIKVHGITDEMLADKPEFKDVAQDFLDYINGAELLIHNAPFDVGFMDYEFRKLNLNVKTD
CEEEECCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEECEEEEEEEEEECCC
DICLVTDTLQMARQMYPGKRSNLDALCERLGIDNSKRTLHGALLDAEILADVYLMMTGGQ
CEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCC
TNLFDEEESVESGVIHVMQEKTAEEIKSAVDFSHNLKLLQPTNDELQAHLEFLKMMNKKS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
GNNCLWDKRFGNNNVH
CCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]