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The map label for this gene is ppe49

Identifier: 148824318

GI number: 148824318

Start: 3503599

End: 3504774

Strand: Reverse

Name: ppe49

Synonym: TBFG_13145

Alternate gene names: 148824318

Gene position: 3504774-3503599 (Counterclockwise)

Preceding gene: 148824319

Following gene: 148824299

Centisome position: 79.21

GC content: 66.24

Gene sequence:

>1176_bases
ATGGTTTTGGGCTTTTCGTGGCTGCCGCCGGAGATCAACTCGGCGCGCATGTTTGCCGGAGCCGGCTCGGGGCCGTTGTT
TGCGGCGGCCTCGGCGTGGGAGGGGCTAGCCGCGGATTTGTGGGCATCGGCATCGTCGTTTGAGTCGGTGCTCGCCGCGT
TGACGACTGGGCCGTGGACCGGTCCGGCGTCGATGTCGATGGCTGCTGCCGCGTCTCCGTATGTCGGGTGGTTGAGCACG
GTGGCGTCGCAGGCGCAGCTGGCGGCCATTCAGGCTCGCGCGGCAGCGACGGCGTTTGAGGCCGCGTTGGCGGCCACGGT
GCATCCGACGGCGGTGACGGCGAATCGGGTGTCGCTGGCGTCGTTGATAGCGGCGAACGTTTTGGGTCAGAACACCCCGG
CGATCGCAGCCACGGAGTTCGATTACCTGGAGATGTGGGCTCAGGATGTGGCTGCGATGGTGGGCTATCACGCTGGGGCA
AAGTCCGTGGCGGCGACGTTGGCGCCATTTAGTCTGCCGCCGGTGAGCTTAGCCGGGTTGGCCGCGCAGGTGGGTACCCA
GGTTGCCGGGATGGCGACGACGGCGTCGGCTGCCGTGACGCCGGTGGTCGAGGGTGCGATGGCGTCGGTGCCGACCGTGA
TGAGCGGGATGCAGTCGCTGGTGTCGCAGCTGCCGTTGCAACATGCGTCGATGTTGTTTCTCCCGGTCCGCATCCTGACG
TCGCCGATAACGACGTTGGCGAGTATGGCGCGTGAAAGCGCGACCAGGTTAGGTCCGCCGGCTGGCGGGTTGGCTGCCGC
GAATACGCCGAACCCGAGTGGTGCGGCTATTCCGGCGTTCAAGCCGCTAGGCGGTCGGGAATTGGGTGCGGGGATGTCCG
CTGGCTTAGGGCAGGCTCAGTTGGTGGGGTCGATGTCGGTGCCGCCGACGTGGCAGGGGTCGATACCCATTTCGATGGCT
TCTTCAGCGATGTCCGGGTTGGGTGTGCCGCCTAACCCAGTCGCGCTGACGCAGGCGGCCGGGGCCGCCGGTGGTGGTAT
GCCGATGATGCTGATGCCAATGAGTATTAGCGGTGCCGGCGCTGGTATGCCCGGTGGGCTGATGGATCGTGATGGTGCGG
GTTGGCATGTCACGCAGGCACGTCTCACTGTGATTCCACGAACCGGGGTTGGCTAG

Upstream 100 bases:

>100_bases
AGCCATCGGTGCGTCACGATGTGTCGATTCATTCGGTAACGATTGTTTAGTTAACCCTTGTACGAGACCCTTCTGGGCGG
CTGATTGGGCTGGGGTTGCG

Downstream 100 bases:

>100_bases
CAGCGCGGGTCAGTATTCGTAGTCCGGTCTGTGTGACGGAGGTCGGAGCGGGCTCCGGCTCGACAACATCGAATCAGCTC
GCTTGCATTGAGGGGCGTAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLST
VASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGA
KSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILT
SPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMA
SSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG

Sequences:

>Translated_391_residues
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLST
VASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGA
KSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILT
SPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMA
SSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
>Mature_391_residues
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLST
VASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGA
KSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILT
SPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMA
SSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE49_MYCTU (Q7D631)

Other databases:

- EMBL:   BX842582
- EMBL:   AE000516
- PIR:   D70922
- RefSeq:   NP_337735.1
- RefSeq:   YP_177932.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q7D631
- SMR:   Q7D631
- EnsemblBacteria:   EBMYCT00000001534
- EnsemblBacteria:   EBMYCT00000071211
- GeneID:   888892
- GeneID:   923472
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3209
- KEGG:   mtu:Rv3125c
- TIGR:   MT3209
- TubercuList:   Rv3125c
- GeneTree:   EBGT00050000014889
- HOGENOM:   HBG572308
- OMA:   VDLWASA
- ProtClustDB:   CLSK799898
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 38586; Mature: 38586

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWT
CEECCCCCCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GPASMSMAAAASPYVGWLSTVASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
SLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGAKSVAATLAPFSLPPVSLAGL
HHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHH
AAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHH
LVGSMSVPPTWQGSIPISMASSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAG
HEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCC
AGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
CCCCCCCCCCCCCCEEEEEEEEEEECCCCCC
>Mature Secondary Structure
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAADLWASASSFESVLAALTTGPWT
CEECCCCCCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GPASMSMAAAASPYVGWLSTVASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
SLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGAKSVAATLAPFSLPPVSLAGL
HHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHH
AAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHH
LVGSMSVPPTWQGSIPISMASSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAG
HEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCC
AGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
CCCCCCCCCCCCCCEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036