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The map label for this gene is ilvH

Identifier: 148824192

GI number: 148824192

Start: 3372333

End: 3372839

Strand: Reverse

Name: ilvH

Synonym: TBFG_13017

Alternate gene names: 148824192

Gene position: 3372839-3372333 (Counterclockwise)

Preceding gene: 148824193

Following gene: 148824191

Centisome position: 76.23

GC content: 62.52

Gene sequence:

>507_bases
ATGAGCCCGAAGACGCACACGTTGTCGGTGTTGGTCGAAGACAAGCCCGGCGTGCTGGCGCGGGTGGCGGCGCTGTTCTC
CCGGCGCGGTTTCAACATCGAGTCGTTGGCGGTGGGTGCCACCGAGTGCAAGGACAGGTCACGGATGACCATCGTGGTCT
CCGCCGAGGACACTCCGCTCGAGCAGATCACCAAGCAGCTCAACAAGCTGATCAACGTCATCAAGATCGTCGAGCAGGAC
GACGAGCACTCGGTGTCACGGGAATTGGCGCTCATCAAGGTCCAAGCCGACGCCGGCAGCCGCAGCCAAGTGATCGAAGC
GGTGAATCTGTTTCGCGCCAACGTGATTGACGTATCCCCGGAGTCATTGACCGTCGAGGCCACCGGTAACCGCGGCAAGT
TAGAGGCCCTGCTGCGGGTGTTGGAGCCGTTCGGTATTCGCGAAATCGCCCAATCCGGAATGGTGTCGCTGTCCCGCGGT
CCGCGCGGCATCGGCACCGCCAAGTAG

Upstream 100 bases:

>100_bases
AAGTGTGGCCGATGGTGGCCGCGGGCACCAGCAATGACGAGATCCAGGCCGCCCGCGGCATTCGCCCCCTGTTCGACGAC
ATCACCGAAGGCCACGCCTG

Downstream 100 bases:

>100_bases
CTAGCAGGTAAGGAGAGATTCAGCGGTGGCACTAGAGATGTTCTACGACGACGACGCAGACCTGTCGATCATTCAGGGCC
GCAAGGTTGGTGTGATCGGC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQD
DEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRG
PRGIGTAK

Sequences:

>Translated_168_residues
MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQD
DEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRG
PRGIGTAK
>Mature_167_residues
SPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDD
EHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGP
RGIGTAK

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=156, Percent_Identity=44.8717948717949, Blast_Score=127, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319837, Length=212, Percent_Identity=30.6603773584906, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_MYCBO (P65162)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856672.1
- ProteinModelPortal:   P65162
- SMR:   P65162
- EnsemblBacteria:   EBMYCT00000015920
- GeneID:   1093699
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3027c
- GeneTree:   EBGT00050000016800
- HOGENOM:   HBG335310
- OMA:   IERELAM
- ProtClustDB:   PRK11895
- BioCyc:   MBOV233413:MB3027C-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 18187; Mature: 18056

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPL
CCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHEECCCHHCCCCCCEEEEEECCCCCH
EQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSP
HHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCEEEECC
ESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRGIGTAK
CEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
SPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPL
CCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHEECCCHHCCCCCCEEEEEECCCCCH
EQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSP
HHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCEEEECC
ESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRGIGTAK
CEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972