Click here to switch to the map view.

The map label for this gene is PE_PGRS44

Identifier: 148823786

GI number: 148823786

Start: 2934868

End: 2936499

Strand: Direct

Name: PE_PGRS44

Synonym: TBFG_12611

Alternate gene names: 148823786

Gene position: 2934868-2936499 (Clockwise)

Preceding gene: 148823785

Following gene: 148823790

Centisome position: 66.33

GC content: 73.04

Gene sequence:

>1632_bases
ATGTCGTTTGTCACGGCAGCTCCAGAGATGCTGGCGACGGCGGCGCAGAATGTCGCGAATATCGGCACATCGCTGAGTGC
GGCAAACGCGACGGCAGCGGCGTCCACGACCTCGGTGCTGGCGGCCGGAGCCGACGAGGTATCGCAGGCTATCGCAAGGC
TGTTCAGTGATTACGCCACGCACTATCAGTCGCTGAACGCTCAAGCCGCGGCATTTCATCACAGCTTCGTGCAAACGTTG
AACGCCGCCGGTGGCGCCTATTCGAGCGCCGAGGCGGCCAACGCTTCGGCGCAGGCGTTGGAACAGAATCTGTTGGCCGT
GATCAATGCGCCCGCCCAGGCGTTGTTCGGGCGTCCCCTGATCGGCAATGGCGCGAATGGAACAGCGGCCAGCCCCAACG
GCGGTGATGGTGGGATTTTGTACGGCAACGGCGGCAACGGCTTCTCCCAAACGACCGCCGGGGTGGCCGGCGGCGCCGGT
GGTTCCGCGGGCCTGATCGGCAACGGCGGCAATGGTGGCGCCGGTGGGGCCGGTGCTGCCGGCGGGGCCGGCGGCGCCGG
CGGATGGCTGCTCGGCAACGGTGGCGCCGGCGGTCCCGGCGGCCCAACGGACGTTCCTGCCGGCACAGGTGGAGCCGGCG
GGGCCGGCGGCGACGCCCCATTGATCGGCTGGGGCGGCAACGGCGGGCCCGGCGGTTTCGCTGCTTTTGGAAACGGTGGG
GCCGGCGGCAACGGCGGCGCCAGCGGTTCGCTCTTTGGCGTCGGCGGCGCCGGCGGCGTCGGCGGATCGAGCGAAGACGT
CGGCGGCACCGGCGGGGCCGGCGGCGCTGGCCGCGGTCTATTCCTTGGCCTGGGCGGTGATGGCGGCGCCGGCGGCACCA
GCAACAACAACGGCGGTGACGGTGGCGCCGGCGGCACCGCGGGAGGTCGATTGTTCAGCCTGGGCGGTGACGGTGGCAAC
GGTGGTGCCGGTACCGCAATCGGATCCAACGCCGGTGACGGTGGCGCCGGCGGTGACAGCAGCGCCCTGATCGGCTACGC
CCAGGGCGGCTCCGGCGGCCTCGGCGGCTTCGGCGAAAGTACCGGCGGCGACGGCGGCCTGGGCGGCGCCGGCGCTGTGC
TCATCGGCACGGGCGTCGGCGGTTTCGGCGGCCTCGGTGGCGGCTCCAACGGCACCGGGGGCGCGGGCGGCGCGGGCGGC
ACGGGCGCCACGCTGATCGGCCTGGGCGCCGGCGGCGGCGGCGGCATCGGCGGGTTCGCCGTCAACGTGGGCAACGGCGT
CGGCGGTCTGGGCGGCCAGGGCGGCCAGGGCGCCGCGCTGATCGGCCTGGGCGCCGGCGGTGCCGGCGGTGCCGGCGGCG
CCACAGTCGTTGGACTTGGTGGCAATGGCGGTGACGGCGGTGACGGTGGCGGCCTGTTTAGTATCGGCGTCGGTGGGGAC
GGCGGCAACGCCGGCAACGGCGCCATGCCTGCCAATGGCGGCAACGGCGGCAACGCCGGGGTCATTGCCAACGGCTCCTT
TGCCCCGTCGTTCGTCGGCTTCGGCGGCAACGGCGGCAACGGCGTCAATGGCGGCACCGGCGGCAGCGGCGGGATCCTTT
TTGGCGCCAACGGCGCGAACGGACCGTCGTAG

Upstream 100 bases:

>100_bases
GAAGCGCGAAAAATGGCAGACCCCGACGGAGGCCCTCTGAAAGAGTCTTGATCATCAGGGCGCGTGACATGTGTCACATG
ACGGGTTGGGAGGGTGGCTG

Downstream 100 bases:

>100_bases
CGGGTCCTCCAGCGCACTACTCGAACAACCCCGGTTGACTCGCTCCGACCGGTGGCGTCATGCCCAGGTGCGTCCAGGCC
AGGGCGGTGGCCACCCGGCC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTL
NAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAG
GSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGN
GGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGG
TGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGD
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS

Sequences:

>Translated_543_residues
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTL
NAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAG
GSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGN
GGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGG
TGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGD
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS
>Mature_542_residues
SFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLN
AAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGG
SAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGGA
GGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGNG
GAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGT
GATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGDG
GNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PG44_MYCTU (Q50630)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   F70726
- RefSeq:   NP_337168.1
- RefSeq:   YP_177891.1
- ProteinModelPortal:   Q50630
- EnsemblBacteria:   EBMYCT00000001932
- EnsemblBacteria:   EBMYCT00000071792
- GeneID:   887992
- GeneID:   925640
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2668.1
- KEGG:   mtu:Rv2591
- TIGR:   MT2668.1
- TubercuList:   Rv2591
- GeneTree:   EBGT00070000031715
- HOGENOM:   HBG131047
- OMA:   GLFNIGR
- ProtClustDB:   CLSK799918
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 46288; Mature: 46157

Theoretical pI: Translated: 3.69; Mature: 3.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYAT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHEECCCHHHHHCCCC
IGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAA
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
GGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCC
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGES
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGGIGGFA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEE
VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGD
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGAN
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCC
GPS
CCC
>Mature Secondary Structure 
SFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYAT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHEECCCHHHHHCCCC
IGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAA
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
GGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCC
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGES
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGGIGGFA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEE
VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGD
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGAN
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCC
GPS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036