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The map label for this gene is lgrD [H]

Identifier: 148823785

GI number: 148823785

Start: 2931188

End: 2934694

Strand: Direct

Name: lgrD [H]

Synonym: TBFG_12610

Alternate gene names: 148823785

Gene position: 2931188-2934694 (Clockwise)

Preceding gene: 148823784

Following gene: 148823786

Centisome position: 66.25

GC content: 66.18

Gene sequence:

>3507_bases
ATGTCGATCAACGATCAGCGACTGACACGCCGCGTCGAGGACCTATACGCCAGCGACGCCCAGTTCGCCGCCGCCAGTCC
CAACGAGGCGATCACCCAGGCGATCGACCAGCCCGGGGTCGCGCTTCCACAGCTCATCCGTATGGTCATGGAGGGCTACG
CCGATCGGCCGGCACTCGGCCAGCGTGCGCTCCGCTTCGTCACCGACCCCGACAGCGGCCGCACCATGGTCGAGCTACTG
CCGCGGTTCGAGACCATCACCTACCGCGAACTGTGGGCCCGCGCCGGCACATTGGCCACCGCGTTGAGCGCTGAGCCCGC
GATCCGGCCGGGCGACCGGGTTTGCGTGCTGGGCTTCAACAGCGTCGACTACACAACCATCGACATCGCGCTGATCCGGT
TGGGCGCCGTGTCGGTTCCACTGCAGACCAGTGCGCCGGTCACCGGGTTGCGCCCGATCGTCACCGAGACCGAGCCGACG
ATGATCGCCACCAGCATCGACAATCTTGGCGACGCCGTCGAAGTGCTGGCCGGTCACGCCCCGGCCCGGCTGGTCGTATT
CGATTACCACGGCAAGGTTGACACCCACCGCGAGGCCGTCGAAGCCGCCCGAGCTCGGTTGGCCGGCTCGGTGACCATCG
ACACACTTGCCGAACTGATCGAACGCGGCAGGGCGCTGCCGGCCACACCCATTGCCGACAGCGCCGACGACGCGCTGGCG
CTGCTGATTTACACCTCGGGTAGTACCGGCGCACCCAAAGGCGCCATGTATCGCGAGAGCCAGGTGATGAGCTTCTGGCG
CAAGTCGAGTGGCTGGTTCGAGCCGAGCGGTTACCCCTCGATCACGCTGAACTTCATGCCGATGAGCCACGTCGGGGGCC
GTCAGGTGCTCTACGGGACGCTTTCCAACGGCGGTACCGCCTACTTCGTCGCCAAGAGCGACCTGTCGACGCTGTTCGAG
GACCTCGCCCTGGTGCGGCCCACAGAATTGTGCTTCGTGCCGCGCATCTGGGACATGGTGTTCGCAGAGTTCCACAGCGA
GGTCGACCGCCGCTTGGTGGACGGCGCCGATCGAGCGGCGCTGGAAGCGCAGGTGAAGGCCGAGCTGCGGGAGAACGTGC
TCGGCGGACGGTTTGTCATGGCGCTGACCGGTTCCGCGCCGATCTCCGCTGAGATGACGGCGTGGGTCGAGTCCCTGCTG
GCCGACGTGCATTTGGTGGAGGGTTACGGCTCCACCGAGGCCGGGATGGTCCTGAACGACGGCATGGTGCGGCGCCCCGC
GGTGATCGACTACAAGCTGGTCGACGTGCCCGAGCTGGGCTACTTCGGCACCGATCAGCCCTACCCCCGGGGCGAGCTGC
TGGTCAAGACGCAAACCATGTTCCCCGGCTACTACCAGCGCCCGGATGTCACCGCCGAGGTGTTCGACCCCGACGGCTTC
TACCGGACCGGGGACATCATGGCCAAAGTAGGCCCCGACCAGTTCGTCTACCTCGACCGCCGCAACAACGTGCTAAAGCT
CTCCCAGGGCGAGTTCATCGCCGTGTCGAAGCTCGAGGCGGTGTTCGGCGACAGCCCGCTGGTCCGACAGATCTTCATCT
ACGGCAACAGTGCCCGGGCCTACCCGCTGGCGGTGGTTGTCCCGTCCGGGGACGCGCTTTCTCGCCATGGCATCGAGAAT
CTCAAGCCCGTGATCAGCGAGTCCCTGCAGGAGGTAGCGAGGGCGGCCGGCCTGCAATCCTACGAGATTCCACGCGACTT
CATCATCGAAACCACGCCGTTCACCCTGGAGAACGGCCTGCTCACCGGCATCCGCAAGCTGGCACGCCCGCAGTTGAAGA
AGTTCTATGGCGAACGTCTCGAGCGGCTCTATACCGAGCTGGCCGATAGCCAATCCAACGAGCTGCGCGAGCTGCGGCAA
AGCGGTCCCGATGCGCCGGTGCTTCCGACGCTGTGCCGTGCCGCGGCTGCGTTGCTGGGCTCTACCGCTGCGGATGTGCG
GCCGGACGCGCACTTCGCCGACCTGGGTGGTGACTCGCTCTCGGCGCTGTCGTTGGCCAACCTGCTGCACGAGATCTTCG
GCGTCGACGTGCCGGTGGGTGTCATTGTCAGCCCGGCAAGCGACCTGCGGGCCCTGGCCGACCACATCGAAGCAGCGCGC
ACCGGCGTCAGGCGACCCAGCTTCGCCTCGATACACGGTCGCTCCGCGACGGAAGTGCACGCCAGCGACCTCACGCTGGA
CAAGTTCATCGACGCTGCCACCCTGGCCGCAGCCCCGAACCTGCCGGCACCGAGCGCCCAAGTGCGCACCGTACTGCTGA
CCGGCGCCACCGGCTTTTTGGGTCGCTACCTGGCGCTGGAATGGCTCGACCGCATGGACCTGGTCAACGGCAAGCTGATC
TGCCTGGTCCGCGCCAGATCCGACGAGGAAGCACAAGCCCGGCTGGACGCGACGTTCGATAGCGGCGACCCGTATTTGGT
GCGGCACTACCGCGAATTGGGCGCCGGCCGCCTCGAGGTGCTCGCCGGCGACAAGGGCGAGGCCGACCTGGGCCTGGACC
GGGTCACCTGGCAGCGGCTAGCCGACACGGTGGACCTGATCGTGGACCCCGCGGCCCTGGTCAACCACGTGCTGCCGTAT
AGCCAGCTGTTCGGCCCAAACGCGGCGGGCACCGCCGAGTTGCTTCGGCTGGCGCTGACCGGCAAGCGCAAGCCATACAT
CTACACCTCGACGATCGCCGTGGGCGAGCAGATCCCGCCGGAGGCGTTCACCGAGGACGCCGACATCCGGGCCATCAGCC
CGACCCGCAGGATCGACGACAGCTACGCCAACGGCTACGCGAACAGCAAGTGGGCCGGCGAGGTGCTGCTGCGCGAAGCT
CACGAGCAGTGCGGCCTGCCGGTGACGGTCTTCCGCTGCGACATGATCCTGGCCGACACCAGCTATACCGGTCAGCTCAA
CCTGCCGGACATGTTCACCCGGCTGATGCTGAGCCTGGCCGCTACCGGCATCGCACCCGGTTCGTTCTATGAGCTGGATG
CGCACGGCAATCGGCAACGCGCCCACTATGACGGCTTGCCGGTCGAATTCGTCGCAGAAGCCATTTGCACCCTTGGGACA
CATAGCCCGGACCGTTTTGTCACCTACCACGTGATGAACCCCTACGACGACGGCATCGGGCTGGACGAGTTCGTCGACTG
GCTCAACTCCCCAACTAGCGGGTCCGGTTGCACGATCCAGCGGATCGCCGACTACGGCGAGTGGCTGCAGCGGTTCGAGA
CTTCGCTGCGTGCCTTGCCGGATCGCCAGCGCCACGCCTCGCTGCTGCCCTTGCTGCACAACTACCGAGAGCCTGCAAAG
CCGATATGCGGGTCAATCGCGCCCACCGACCAGTTCCGCGCTGCCGTCCAAGAAGCGAAAATCGGTCCGGACAAAGACAT
TCCGCACCTCACGGCGGCGATCATCGCGAAGTACATCAGCAACCTGCGACTGCTCGGGCTGCTGTGA

Upstream 100 bases:

>100_bases
TTGCATTGTGTAATATATTTACTTTAGCTAACGTTCTATTGGTCGGGCGCAGCGCCGCGCCGTCGATTTCCCACCCTTTC
CGGCACGCCGAGGTGACCGC

Downstream 100 bases:

>100_bases
TCGGGCCTGGCCGCCGCGGCGCCGGGTAACCAAGCAGCCCGTTACGCCCAGTTCGCCTATGAGAAGGCAGTAAGAAGCGC
GAAAAATGGCAGACCCCGAC

Product: fatty-acid-CoA ligase fadD9

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1168; Mature: 1167

Protein sequence:

>1168_residues
MSINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELL
PRFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFNSVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPT
MIATSIDNLGDAVEVLAGHAPARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALA
LLIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTLFE
DLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAALEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLL
ADVHLVEGYGSTEAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGF
YRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHGIEN
LKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQ
SGPDAPVLPTLCRAAAALLGSTAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAAR
TGVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLI
CLVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPY
SQLFGPNAAGTAELLRLALTGKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREA
HEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGT
HSPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAK
PICGSIAPTDQFRAAVQEAKIGPDKDIPHLTAAIIAKYISNLRLLGLL

Sequences:

>Translated_1168_residues
MSINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELL
PRFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFNSVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPT
MIATSIDNLGDAVEVLAGHAPARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALA
LLIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTLFE
DLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAALEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLL
ADVHLVEGYGSTEAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGF
YRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHGIEN
LKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQ
SGPDAPVLPTLCRAAAALLGSTAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAAR
TGVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLI
CLVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPY
SQLFGPNAAGTAELLRLALTGKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREA
HEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGT
HSPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAK
PICGSIAPTDQFRAAVQEAKIGPDKDIPHLTAAIIAKYISNLRLLGLL
>Mature_1167_residues
SINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLP
RFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFNSVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPTM
IATSIDNLGDAVEVLAGHAPARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALAL
LIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTLFED
LALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAALEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLA
DVHLVEGYGSTEAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGFY
RTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHGIENL
KPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQS
GPDAPVLPTLCRAAAALLGSTAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAART
GVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLIC
LVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPYS
QLFGPNAAGTAELLRLALTGKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREAH
EQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH
SPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAKP
ICGSIAPTDQFRAAVQEAKIGPDKDIPHLTAAIIAKYISNLRLLGLL

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI57165410, Length=595, Percent_Identity=27.0588235294118, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI40807491, Length=598, Percent_Identity=28.0936454849498, Blast_Score=199, Evalue=2e-50,
Organism=Homo sapiens, GI57165412, Length=594, Percent_Identity=27.1043771043771, Blast_Score=198, Evalue=3e-50,
Organism=Homo sapiens, GI42794756, Length=595, Percent_Identity=25.8823529411765, Blast_Score=192, Evalue=2e-48,
Organism=Homo sapiens, GI42794760, Length=595, Percent_Identity=25.8823529411765, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI42794758, Length=595, Percent_Identity=25.8823529411765, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI42794754, Length=647, Percent_Identity=25.0386398763524, Blast_Score=163, Evalue=8e-40,
Organism=Homo sapiens, GI42794752, Length=647, Percent_Identity=25.0386398763524, Blast_Score=163, Evalue=8e-40,
Organism=Homo sapiens, GI4758332, Length=689, Percent_Identity=24.8185776487663, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI12669909, Length=689, Percent_Identity=24.6734397677794, Blast_Score=156, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556552, Length=601, Percent_Identity=26.7886855241265, Blast_Score=192, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17510401, Length=451, Percent_Identity=32.3725055432373, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17564090, Length=473, Percent_Identity=27.6955602536998, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553312, Length=643, Percent_Identity=25.3499222395023, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193204819, Length=635, Percent_Identity=24.7244094488189, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541856, Length=465, Percent_Identity=26.4516129032258, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25147511, Length=465, Percent_Identity=27.3118279569892, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17531443, Length=430, Percent_Identity=25.3488372093023, Blast_Score=87, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320852, Length=459, Percent_Identity=27.0152505446623, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323903, Length=473, Percent_Identity=26.6384778012685, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322182, Length=615, Percent_Identity=24.5528455284553, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324893, Length=447, Percent_Identity=24.3847874720358, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319591, Length=676, Percent_Identity=25.5917159763314, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281366413, Length=659, Percent_Identity=26.7071320182094, Blast_Score=206, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24666501, Length=659, Percent_Identity=26.7071320182094, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666497, Length=659, Percent_Identity=26.7071320182094, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI62471689, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471679, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471683, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471685, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24586636, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471681, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471687, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24586634, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI22026970, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 127329; Mature: 127198

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50075 ACP_DOMAIN ; PS00061 ADH_SHORT ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALG
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
QRALRFVTDPDSGRTMVELLPRFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFN
HHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
SVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEVLAGHA
CCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCEECCCCCEEEECHHHHHHHHHHHHCCC
PARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALA
CEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LLIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGT
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEE
LSNGGTAYFVAKSDLSTLFEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAA
ECCCCEEEEEECHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAGMVLND
HHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEECC
GMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGF
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCC
YRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARA
EECCCEEEEECCCEEEEEECCCCEEEECCCCEEEHHHHHHHHCCCCCEEEEEEECCCCCC
YPLAVVVPSGDALSRHGIENLKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGL
EEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCEECCHH
LTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
STAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAAR
CCHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
TGVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFL
HCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCHHHH
GRYLALEWLDRMDLVNGKLICLVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEV
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEE
LAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCCHHHHHHHHHC
GKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREA
CCCCCEEEEEEEECCCCCCHHHCCCCCCEEEECCHHHCCCHHHCCCCCCCHHHHHHHHHH
HEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQR
HHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
AHYDGLPVEFVAEAICTLGTHSPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQ
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHH
RIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAKPICGSIAPTDQFRAAVQEAK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHC
IGPDKDIPHLTAAIIAKYISNLRLLGLL
CCCCCCCHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALG
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
QRALRFVTDPDSGRTMVELLPRFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFN
HHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
SVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEVLAGHA
CCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCEECCCCCEEEECHHHHHHHHHHHHCCC
PARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALA
CEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LLIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGT
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEE
LSNGGTAYFVAKSDLSTLFEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAA
ECCCCEEEEEECHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAGMVLND
HHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEECC
GMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGF
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCC
YRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARA
EECCCEEEEECCCEEEEEECCCCEEEECCCCEEEHHHHHHHHCCCCCEEEEEEECCCCCC
YPLAVVVPSGDALSRHGIENLKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGL
EEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCEECCHH
LTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
STAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAAR
CCHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
TGVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFL
HCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHEEEEEEECCHHHH
GRYLALEWLDRMDLVNGKLICLVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEV
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEE
LAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCCHHHHHHHHHC
GKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREA
CCCCCEEEEEEEECCCCCCHHHCCCCCCEEEECCHHHCCCHHHCCCCCCCHHHHHHHHHH
HEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQR
HHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
AHYDGLPVEFVAEAICTLGTHSPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQ
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHH
RIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAKPICGSIAPTDQFRAAVQEAK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHC
IGPDKDIPHLTAAIIAKYISNLRLLGLL
CCCCCCCHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA