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The map label for this gene is rnpA [H]

Identifier: 148663790

GI number: 148663790

Start: 4418857

End: 4419234

Strand: Reverse

Name: rnpA [H]

Synonym: MRA_3962

Alternate gene names: 148663790

Gene position: 4419234-4418857 (Counterclockwise)

Preceding gene: 148663791

Following gene: 148663789

Centisome position: 99.98

GC content: 62.96

Gene sequence:

>378_bases
TTGATTGCAACACCGGGCTTATTTGCGGTGCTTCGTGCACGCAACCGCATGAGGCGGTCAGCGGATTTTGAAACAACGGT
GAAGCACGGGATGCGTACCGTGCGGTCTGACATGGTCGTTTATTGGTGGCGTGGGAGTGGCGGTGGGCCGCGCGTCGGAC
TGATTATCGCCAAGTCGGTGGGGTCGGCCGTGGAACGCCACCGCGTGGCACGTCGGCTGCGGCACGTGGCTGGGTCGATC
GTCAAAGAACTCCACCCGTCCGATCATGTGGTGATCCGCGCGCTGCCGAGCAGCCGGCATGTCTCCTCGGCTCGGTTGGA
GCAGCAACTGCGATGCGGCTTGCGGAGGGCTGTCGAACTGGCAGGTAGTGATCGGTGA

Upstream 100 bases:

>100_bases
GGCGAGCTCGTGTTCACGGTTTCCGCTTACGGATGCGTACCCGCGCCGGGAGGTCAATTGTGTCCAGCCGGCGACGCAAG
GGTCGGCGCACGCTCAGTGC

Downstream 100 bases:

>100_bases
GTCTGTCTAGGCAAAGCTGTGGGCGCGTGGTCCGGGTTACCGGTAGAGCATCAGCGCGGGGGTTGATTTTCGTTATCCAG
GTCTATCGGCACATGCTTTC

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSVGSAVERHRVARRLRHVAGSI
VKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVELAGSDR

Sequences:

>Translated_125_residues
MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSVGSAVERHRVARRLRHVAGSI
VKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVELAGSDR
>Mature_125_residues
MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSVGSAVERHRVARRLRHVAGSI
VKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVELAGSDR

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 13942; Mature: 13942

Theoretical pI: Translated: 12.38; Mature: 12.38

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEHEEHHHH
GSAVERHRVARRLRHVAGSIVKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AGSDR
HCCCC
>Mature Secondary Structure
MIATPGLFAVLRARNRMRRSADFETTVKHGMRTVRSDMVVYWWRGSGGGPRVGLIIAKSV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEHEEHHHH
GSAVERHRVARRLRHVAGSIVKELHPSDHVVIRALPSSRHVSSARLEQQLRCGLRRAVEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AGSDR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]