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The map label for this gene is ppe69

Identifier: 148663759

GI number: 148663759

Start: 4382930

End: 4384129

Strand: Reverse

Name: ppe69

Synonym: MRA_3931

Alternate gene names: 148663759

Gene position: 4384129-4382930 (Counterclockwise)

Preceding gene: 148663760

Following gene: 148663758

Centisome position: 99.19

GC content: 71.0

Gene sequence:

>1200_bases
ATGCCCGATCCAGGATGGGCTGCGCGGACACCTGAGGCCAACGACCTGCTGCTCACGGCGGGCACCGGCGTGGGCACCCA
TCTGGCCAATCAAACGGCGTGGACCACACTGGGCGCCAGCCACCACGCCTCGGGTGTCGCGTCGGCGATCAACACCGCCG
CCACCGCGGCGAGCTGGTTGGGTGTCGGGTCGGCGGCCTCGGCGCTTAACGTCACCATGCTCAACGCCACGCTGCACGGA
CTGGCCGGCTGGGTCGACGTGAAGCCGGCCGTGGTATCGACCGCGATCGCGGCGTTTGAGACCGCCAACGCGGCCATGCG
CCCTGCCCCCGAGTGCATGGAGAACCGCGACGAATGGGGCGTCGACAACGCCATCAACCCCAGCGTGCTGTGGACACTAA
CGCCTCGAATCGTCTCTTTGGACGTCGAGTATTTCGGGGTGATGTGGCCGAATAACGCCGCGGTGGGCGCCACCTACGGA
GGGGTTCTCGCCGCGCTGGCCGAGAGTCTGGCAATTCCGCCGCCGGTCGCGACCATGGGTGCATCTCCGGCCGCTCCGGC
ACAGGCTGCGGCGGCGGTTGGCCAGGCGGCCGCCGAGGCCGCGGCCGGTGACGGGATGCGTTCCGCCTACCAGGGCGTGC
AGGCAGGGTCAACCGGCGCGGGTCAGTCAACGTCGGCGGGTGAGAACTTCGGCAATCAGCTCAGCACGTTCATGCAGCCG
ATGCAGGCGGTGATGCAAGCGGCCCCGCAGGCGCTGCAGGCGCCGTCGGGACTGATGCAGGCACCGATGAGCGCGATGCA
GCCGCTGCAATCGATGGTGGGCATGTTCGCCAACCCGGGCGCACTGGGCATGGGCGGGGCGGCGCCGGGAGCCTCGGCGG
CTTCGGCGGCCGGTGGGATATCGGCCGCGGCCACCGAGGTCGGTGCGGGCGGCGGAGGCGCCGCCCTGGGCGGCGGCGGT
ATGCCAGCGACGAGCTTCACACGTCCCGTCAGCGCTTTCGAATCGGGCACCAGCGGCAGGCCGGTCGGGTTGCGGCCCAG
CGGGGCTTTGGGCGCCGACGTCGTGCGCGCGCCGACGACCACGGTGGGTGGCACCCCTATCGGAGGCATGCCGGTCGGAC
ATGCGGCGGGGGGTCACCGCGGATCCCATGGCAAGTCCGAGCAGGCCGCGACGGTGCGTGTTGTCGATGACCGGCGGTAG

Upstream 100 bases:

>100_bases
GCGCGGCCTGTTCGCGGGTTAGCAGGGCCTCGCGTCGGGCGTGTACGTGACCACAGAAGCGGCGCGCGCGGCGGCATCGG
CGCTGCAAGGGTAAGTAGGC

Downstream 100 bases:

>100_bases
ATCTAGCTCGGGCACAGGGTGAATCGACAGGTCCGCAGAGCAGCCATACACTTCGCGTCATGCCCCGATATTTGAGGGGG
AACGGCTAACGGCAGTAAAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWLGVGSAASALNVTMLNATLHG
LAGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWGVDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYG
GVLAALAESLAIPPPVATMGASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQP
MQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGISAAATEVGAGGGGAALGGGG
MPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTTTVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR

Sequences:

>Translated_399_residues
MPDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWLGVGSAASALNVTMLNATLHG
LAGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWGVDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYG
GVLAALAESLAIPPPVATMGASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQP
MQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGISAAATEVGAGGGGAALGGGG
MPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTTTVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR
>Mature_398_residues
PDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWLGVGSAASALNVTMLNATLHGL
AGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWGVDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYGG
VLAALAESLAIPPPVATMGASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQPM
QAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGISAAATEVGAGGGGAALGGGGM
PATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTTTVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE69_MYCTU (Q79F90)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   E70598
- RefSeq:   NP_338560.1
- RefSeq:   YP_178024.1
- ProteinModelPortal:   Q79F90
- SMR:   Q79F90
- EnsemblBacteria:   EBMYCT00000000831
- EnsemblBacteria:   EBMYCT00000072638
- GeneID:   886227
- GeneID:   926437
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4007
- KEGG:   mtu:Rv3892c
- TIGR:   MT4007
- TubercuList:   Rv3892c
- GeneTree:   EBGT00050000014889
- HOGENOM:   HBG131199
- OMA:   APMQMMQ
- ProtClustDB:   CLSK800029
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 38853; Mature: 38722

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWL
CCCCCCCCCCCCCCCEEEECCCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GVGSAASALNVTMLNATLHGLAGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWG
CCCCHHHHHEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHCC
VDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYGGVLAALAESLAIPPPVATMG
CCCCCCCCEEEEECCEEEEEEHHHEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCC
ASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
MQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCC
SAAATEVGAGGGGAALGGGGMPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTT
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCC
TVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
PDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWL
CCCCCCCCCCCCCCEEEECCCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GVGSAASALNVTMLNATLHGLAGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWG
CCCCHHHHHEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHCC
VDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYGGVLAALAESLAIPPPVATMG
CCCCCCCCEEEEECCEEEEEEHHHEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCC
ASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
MQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCC
SAAATEVGAGGGGAALGGGGMPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTT
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCC
TVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036