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The map label for this gene is esxC

Identifier: 148663757

GI number: 148663757

Start: 4382172

End: 4382459

Strand: Reverse

Name: esxC

Synonym: MRA_3929

Alternate gene names: NA

Gene position: 4382459-4382172 (Counterclockwise)

Preceding gene: 148663758

Following gene: 148663756

Centisome position: 99.15

GC content: 60.76

Gene sequence:

>288_bases
ATGTCAGATCAAATCACGTATAACCCGGGAGCCGTATCCGACTTCGCTTCCGACGTGGGCTCGCGCGCCGGCCAGCTCCA
CATGATTTACGAAGACACCGCCAGCAAAACAAATGCGCTGCAAGAGTTTTTCGCGGGCCACGGCGCGCAAGGGTTTTTCG
ACGCCCAGGCGCAGATGCTGTCGGGGCTGCAGGGGCTCATTGAGACGGTGGGTCAGCATGGGACTACCACCGGCCACGTG
CTGGACAACGCGATCGGAACCGACCAGGCCATCGCGGGCTTGTTCTAA

Upstream 100 bases:

>100_bases
AGGGACACGAGGCGGACTCGCAGACAGCGTTTCAGGCGCTGTTCGGCGCTAGCCACGGATCCTGACCCAACTCGTTTCAC
GCCTCGGAAAGGAATTTCAC

Downstream 100 bases:

>100_bases
AGCCGGCCGTGGGCCGAGTGAAGGTGGGGTACATGCGCGGACCGCGCGTCTGCCCCACCTTCTGCTTGCTGCTAGCTGGT
TGAGATGAACGTGACATGCT

Product: esat-6 like protein EsxC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MSDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDAQAQMLSGLQGLIETVGQHGTTTGHV
LDNAIGTDQAIAGLF

Sequences:

>Translated_95_residues
MSDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDAQAQMLSGLQGLIETVGQHGTTTGHV
LDNAIGTDQAIAGLF
>Mature_94_residues
SDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDAQAQMLSGLQGLIETVGQHGTTTGHVL
DNAIGTDQAIAGLF

Specific function: Unknown

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ES6LB_MYCTU (O05454)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   C70598
- RefSeq:   NP_218407.1
- RefSeq:   NP_338558.1
- ProteinModelPortal:   O05454
- EnsemblBacteria:   EBMYCT00000001133
- EnsemblBacteria:   EBMYCT00000072679
- GeneID:   886222
- GeneID:   922527
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4005
- KEGG:   mtu:Rv3890c
- TIGR:   MT4005
- TubercuList:   Rv3890c
- GeneTree:   EBGT00050000017901
- HOGENOM:   HBG571199
- OMA:   NAIGADQ
- ProtClustDB:   CLSK792791
- InterPro:   IPR010310
- InterPro:   IPR020167
- ProDom:   PD065399

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 9920; Mature: 9789

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDAQAQML
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
SGLQGLIETVGQHGTTTGHVLDNAIGTDQAIAGLF
HHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDAQAQML
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
SGLQGLIETVGQHGTTTGHVLDNAIGTDQAIAGLF
HHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036