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The map label for this gene is glpQ1

Identifier: 148663710

GI number: 148663710

Start: 4323184

End: 4324008

Strand: Reverse

Name: glpQ1

Synonym: MRA_3882

Alternate gene names: 148663710

Gene position: 4324008-4323184 (Counterclockwise)

Preceding gene: 148663711

Following gene: 148663706

Centisome position: 97.83

GC content: 66.55

Gene sequence:

>825_bases
ATGACATGGGCCGACGAGGTGCTCGCCGGACATCCCTTTGTGGTTGCTCACCGTGGTGCGTCGGCGGCTCGGCCGGAGCA
TACCCTTGCCGCCTACGACCTGGCGCTCAAAGAGGGCGCCGACGGCGTGGAATGTGATGTGCGGTTGACCCGGGACGGGC
ATCTGGTCTGTGTGCATGACCGCCGCCTGGACCGAACCTCGACGGGAGCCGGCTTGGTCAGCACGATGACGCTGGCCCAG
CTACGCGAGCTGGAGTACGGCGCGTGGCACGACAGCTGGCGCCCCGACGGTTCGCACGGCGACACCAGTCTGCTGACCCT
GGACGCGCTTGTTTCGCTGGTTTTGGACTGGCACCGGCCGGTGAAGATCTTCGTCGAGACCAAGCATCCCGTCCGATACG
GCTCGCTGGTGGAAAACAAGCTGCTGGCGCTGCTACACCGGTTCGGTATTGCCGCACCCGCCTCCGCAGATCGATCCCGT
GCGGTGGTGATGTCGTTTTCGGCCGCCGCGGTCTGGCGGATCCGGCGGGCTGCACCGCTGCTGCCGACGGTGTTGCTCGG
CAAGACCCCCCGATACCTGACCAGCAGTGCGGCCACGGCGGTCGGGGCAACCGCCGTGGGACCCTCACTGCCTGCGTTAA
AGGAATATCCGCAACTCGTTGACCGCTCGGCAGCTCAGGGCCGGGCGGTGTACTGCTGGAACGTCGATGAGTACGAGGAC
ATCGACTTTTGCCGGGAGGTCGGGGTGGCCTGGATTGGTACTCACCACCCCGGCCGCACCAAGGCCTGGCTGGAAGACGG
GCGGGCGAACGGGACCACTCGCTGA

Upstream 100 bases:

>100_bases
CAGCGCATCGCTGGGTGGTGGTGAACACAGACGGGCGTTCCGCGCCGGCATCTTCTGTTGCGGTTGAGTTGGACGGGCAG
GAACCGGCAGCATAGTGGAC

Downstream 100 bases:

>100_bases
TCCCCGCCAGGGATCTAGAGGCGGCCCCCGGCAGCGTGCGGGGCGCCTGATGCGGCCGGCGCCACATCCACTTCACGTGC
GACGAAGTTCTCTAGCTCGA

Product: putative glycerophosphoryl diester phosphodiesterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase 1

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMTLAQ
LRELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRPVKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSR
AVVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYED
IDFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR

Sequences:

>Translated_274_residues
MTWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMTLAQ
LRELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRPVKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSR
AVVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYED
IDFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR
>Mature_273_residues
TWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTSTGAGLVSTMTLAQL
RELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRPVKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSRA
VVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYEDI
DFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GDPD domain

Homologues:

Organism=Homo sapiens, GI7706617, Length=162, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789858, Length=80, Percent_Identity=37.5, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPQ1_MYCTU (P96236)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   G70653
- RefSeq:   NP_218359.1
- RefSeq:   NP_338503.1
- ProteinModelPortal:   P96236
- SMR:   P96236
- EnsemblBacteria:   EBMYCT00000003022
- EnsemblBacteria:   EBMYCT00000072157
- GeneID:   886177
- GeneID:   926308
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3950
- KEGG:   mtu:Rv3842c
- TIGR:   MT3950
- TubercuList:   Rv3842c
- GeneTree:   EBGT00050000016256
- HOGENOM:   HBG725117
- OMA:   ATNHPGR
- ProtClustDB:   CLSK792754
- InterPro:   IPR004129
- InterPro:   IPR017946
- Gene3D:   G3DSA:3.20.20.190
- PANTHER:   PTHR23344

Pfam domain/function: PF03009 GDPD; SSF51695 PLC-like_Pdiesterase_TIM-brl

EC number: =3.1.4.46

Molecular weight: Translated: 29917; Mature: 29786

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHD
CCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEC
RRLDRTSTGAGLVSTMTLAQLRELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRP
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSRAVVMSFSAAAVWRIRRAAPL
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCC
LPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYED
HHHHHHCCCCHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
IDFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR
HHHHHHCCEEEEECCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
TWADEVLAGHPFVVAHRGASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHD
CCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEC
RRLDRTSTGAGLVSTMTLAQLRELEYGAWHDSWRPDGSHGDTSLLTLDALVSLVLDWHRP
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VKIFVETKHPVRYGSLVENKLLALLHRFGIAAPASADRSRAVVMSFSAAAVWRIRRAAPL
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCC
LPTVLLGKTPRYLTSSAATAVGATAVGPSLPALKEYPQLVDRSAAQGRAVYCWNVDEYED
HHHHHHCCCCHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
IDFCREVGVAWIGTHHPGRTKAWLEDGRANGTTR
HHHHHHCCEEEEECCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036