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The map label for this gene is pheA

Identifier: 148663706

GI number: 148663706

Start: 4320150

End: 4321115

Strand: Reverse

Name: pheA

Synonym: MRA_3878

Alternate gene names: 148663706

Gene position: 4321115-4320150 (Counterclockwise)

Preceding gene: 148663710

Following gene: 148663705

Centisome position: 97.76

GC content: 68.94

Gene sequence:

>966_bases
GTGGTGCGTATCGCTTACCTCGGTCCGGAAGGGACATTCACCGAGGCAGCCCTGGTCCGGATGGTGGCCGCCGGCCTAGT
TCCCGAGACCGGGCCCGATGCACTGCAGCGGATGCCGGTCGAGAGCGCGCCCGCAGCACTGGCTGCGGTCCGCGACGGCG
GTGCGGATTATGCGTGCGTGCCGATCGAGAACTCGATCGACGGTTCCGTGCTGCCTACTTTGGATAGCCTGGCCATCGGT
GTGCGCCTGCAGGTGTTCGCCGAGACAACGCTGGACGTGACGTTCAGCATCGTGGTCAAACCCGGGCGCAACGCCGCGGA
CGTGCGGACCCTGGCGGCCTTTCCGGTGGCGGCTGCACAGGTGCGGCAGTGGTTGGCGGCCCATCTTCCCGCCGCCGACC
TGCGGCCGGCTTATTCCAACGCGGACGCGGCCCGGCAGGTGGCTGACGGCTTGGTTGACGCCGCGGTGACCTCGCCGCTG
GCGGCCGCTCGTTGGGGATTGGCGGCCCTGGCCGACGGTGTCGTTGACGAATCCAATGCCCGCACCCGCTTCGTCCTGGT
TGGTCGGCCCGGGCCGCCTCCGGCGCGCACCGGAGCCGATCGCACGTCTGCAGTGCTGCGCATCGACAACCAGCCCGGTG
CGCTGGTAGCTGCGCTGGCCGAGTTCGGCATCCGCGGCATCGATCTCACTCGGATTGAATCCCGGCCCACCCGTACCGAA
CTTGGCACCTATCTGTTCTTCGTGGATTGCGTCGGCCACATCGACGACGAGGCCGTCGCCGAGGCACTCAAGGCGGTGCA
CCGACGTTGTGCTGATGTGCGATACCTGGGGTCCTGGCCGACGGGGCCAGCGGCAGGGGCGCAGCCGCCCCTGGTAGACG
AAGCATCACGCTGGTTAGCGCGGCTCCGCGCGGGCAAACCCGAGCAGACCCTGGTTCGCCCGGACGACCAGGGGGCGCAA
GCATGA

Upstream 100 bases:

>100_bases
GGCATCCACGACCTCCTGTGTTTAGGTAAGCCTAAGTTAACTAATGCACGGTCTGGTCGCAAGAGTTGGCGGTCGGCTTT
GCGTCGTTAGGGTTGTGAGC

Downstream 100 bases:

>100_bases
GCGGTCGTTTGGTGCTGCTGCGGCACGGCCAGTCCTATGGCAACGTCGAGCGCAGGTTGGATACCCTGCCGCCGGGAACG
GCGCTGACACCGCTGGGTCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIG
VRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPL
AAARWGLAALADGVVDESNARTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTE
LGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLARLRAGKPEQTLVRPDDQGAQ
A

Sequences:

>Translated_321_residues
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIG
VRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPL
AAARWGLAALADGVVDESNARTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTE
LGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLARLRAGKPEQTLVRPDDQGAQ
A
>Mature_321_residues
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIG
VRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPL
AAARWGLAALADGVVDESNARTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTE
LGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLARLRAGKPEQTLVRPDDQGAQ
A

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=285, Percent_Identity=26.6666666666667, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_MYCBO (Q7TVJ6)

Other databases:

- EMBL:   BX248347
- RefSeq:   NP_857505.1
- ProteinModelPortal:   Q7TVJ6
- SMR:   Q7TVJ6
- EnsemblBacteria:   EBMYCT00000015537
- GeneID:   1093869
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3868c
- GeneTree:   EBGT00050000015705
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- ProtClustDB:   PRK11898
- BioCyc:   MBOV233413:MB3868C-MONOMER
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 33634; Mature: 33634

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACV
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHCCCCCEEEE
PIENSIDGSVLPTLDSLAIGVRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQ
ECCCCCCCCCCCCHHHHHHCEEEEEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
VRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNA
HHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCC
RTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTE
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCHHH
LGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLA
HHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHHHHHH
RLRAGKPEQTLVRPDDQGAQA
HHHCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACV
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHCCCCCEEEE
PIENSIDGSVLPTLDSLAIGVRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQ
ECCCCCCCCCCCCHHHHHHCEEEEEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
VRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNA
HHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCC
RTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTE
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCHHH
LGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLA
HHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHHHHHH
RLRAGKPEQTLVRPDDQGAQA
HHHCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972