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The map label for this gene is pks13 [H]

Identifier: 148663668

GI number: 148663668

Start: 4264391

End: 4269592

Strand: Reverse

Name: pks13 [H]

Synonym: MRA_3840

Alternate gene names: 148663668

Gene position: 4269592-4264391 (Counterclockwise)

Preceding gene: 148663669

Following gene: 148663667

Centisome position: 96.6

GC content: 68.45

Gene sequence:

>5202_bases
ATGGCTGACGTAGCGGAATCCCAGGAGAACGCCCCCGCCGAAAGGGCCGAGCTAACGGTCCCCGAGATGCGCCAGTGGCT
GCGCAACTGGGTGGGTAAGGCCGTCGGAAAGGCACCGGACTCGATCGACGAATCGGTGCCCATGGTGGAGCTGGGTCTGT
CGTCGCGCGATGCCGTCGCGATGGCCGCCGACATAGAAGACCTGACCGGGGTCACGCTGTCGGTCGCGGTGGCGTTCGCG
CATCCGACCATCGAATCGCTGGCCACCCGGATCATCGAGGGCGAGCCGGAGACCGACCTAGCGGGCGATGACGCCGAAGA
CTGGTCGCGCACCGGCCCGGCCGAGCGCGTCGACATCGCGATCGTGGGCTTGTCCACCCGCTTCCCGGGCGAGATGAACA
CCCCCGAGCAGACCTGGCAGGCGCTGCTGGAAGGCCGCGACGGGATCACCGACCTGCCCGACGGGCGCTGGTCGGAATTC
CTCGAAGAGCCGCGGCTGGCCGCGCGGGTCGCCGGGGCCCGCACCCGGGGCGGCTACCTGAAGGACATCAAGGGCTTCGA
TTCGGAGTTCTTCGCGGTGGCCAAGACCGAAGCCGACAACATCGACCCGCAGCAGCGGATGGCGCTGGAGCTGACCTGGG
AGGCGCTCGAGCACGCCCGCATCCCGGCGTCGAGCCTGCGCGGCCAGGCCGTCGGTGTGTACATCGGCAGCTCCACCAAC
GACTACAGCTTCCTGGCGGTGTCGGACCCGACGGTCGCGCACCCGTATGCGATCACCGGCACCAGCAGCTCGATCATCGC
CAACCGGGTGTCCTACTTCTACGACTTCCACGGACCGTCGGTCACCATTGACACCGCGTGCTCGAGTTCGCTGGTGGCCA
TCCACCAGGGGGTGCAGGCGCTGCGCAACGGCGAGGCCGACGTAGTGGTCGCCGGCGGGGTGAACGCGTTGATCACACCG
ATGGTCACCCTGGGTTTCGACGAGATCGGTGCGGTGCTGGCGCCCGACGGCCGGATCAAGTCGTTCTCAGCCGACGCCGA
CGGCTACACCCGCTCCGAAGGCGGCGGCATGCTGGTGCTCAAGCGGGTCGACGACGCCCGCCGCGACGGCGACGCGATCC
TGGCCGTGATCGCCGGCAGCGCGGTCAACCACGACGGCCGGTCCAACGGCCTGATCGCACCCAACCAGGACGCGCAGGCC
GACGTGCTGCGCCGGGCCTACAAGGACGCCGGCATCGATCCGCGCACCGTCGACTACATCGAGGCGCACGGCACCGGCAC
CATCCTCGGCGACCCAATCGAGGCCGAGGCGCTGGGCCGGGTGGTCGGTAGGGGCCGTCCGGCCGATCGGCCGGCGCTGC
TGGGTGCGGTGAAAACCAACGTCGGGCACCTGGAATCGGCGGCCGGCGCGGCCAGCATGGCCAAGGTGGTGCTGGCGCTG
CAGCACGACAAACTGCCGCCGTCGATCAACTTCGCCGGCCCCAGCCCCTACATCGACTTCGACGCGATGCGGTTGAAGAT
GATCACCACGCCCACCGACTGGCCGCGATACGGCGGCTACGCGCTGGCCGGGGTGTCCAGCTTCGGCTTCGGCGGCGCCA
ACGCGCACGTGGTGGTGCGCGAGGTCCTGCCGCGTGACGTGGTGGAAAAGGAACCGGAACCCGAGCCGGAACCCAAGGCG
GCCGCCGAACCCGCCGAGGCGCCCACGTTGGCAGGCCACGCGCTGCGGTTCGACGAGTTCGGCAACATCATCACCGACTC
GGCGGTCGCCGAAGAGCCGGAGCCCGAACTGCCCGGAGTCACCGAGGAGGCGCTGCGGCTCAAGGAAGCCGCGTTGGAAG
AGCTTGCGGCCCAAGAGGTTACGGCACCATTGGTCCCGTTGGCGGTGTCGGCGTTTCTGACGTCCCGCAAGAAGGCGGCG
GCCGCCGAGTTGGCGGACTGGATGCAAAGCCCGGAAGGCCAGGCCTCCTCGCTGGAATCGATCGGCAGGTCGTTGTCGCG
GCGCAACCACGGCCGTTCCCGCGCGGTGGTGTTGGCCCACGACCACGACGAGGCCATCAAGGGCCTGCGCGCGGTCGCCG
CGGGCAAGCAGGCGCCGAACGTGTTCAGCGTCGACGGGCCGGTGACCACCGGCCCGGTCTGGGTGCTCGCCGGATTCGGC
GCCCAGCATCGCAAGATGGGCAAGAGCCTGTACCTGCGCAACGAGGTGTTCGCGGCGTGGATCGAGAAGGTCGACGCCCT
GGTCCAAGACGAGCTGGGCTACTCGGTGCTGGAGCTGATCCTGGACGACGCGCAGGACTACGGCATCGAGACCACCCAGG
TCACCATCTTCGCGATCCAGATCGCGCTGGGTGAGCTGCTGCGCCATCACGGCGCCAAACCGGCCGCGGTCATCGGCCAG
TCGCTGGGTGAGGCCGCGTCGGCCTACTTCGCCGGCGGGCTGTCGCTGCGGGATGCCACCCGGGCGATCTGCTCGCGCTC
GCACCTGATGGGCGAGGGTGAGGCGATGCTGTTCGGCGAGTACATCCGGTTGATGGCGCTGGTGGAATACTCCGCCGACG
AAATCAGAGAAGTGTTCTCCGACTTCCCCGATCTGGAGGTGTGTGTCTACGCCGCGCCCACCCAGACGGTCATCGGCGGC
CCCCCCGAGCAGGTGGACGCGATCCTTGCCCGCGCCGAGGCCGAGGGCAAGTTCGCCCGCAAATTCGCGACCAAGGGCGC
CAGCCACACCTCGCAGATGGACCCGCTGCTGGGCGAGCTCACCGCGGAGCTGCAAGGCATCAAGCCGACGAGCCCGACGT
GTGGGATCTTCTCGACGGTGCACGAGGGCCGCTACATCAAACCCGGCGGCGAACCCATCCACGACGTCGAATACTGGAAG
AAGGGGCTGCGGCATTCCGTCTACTTCACCCACGGCATCCGCAACGCCGTCGACAGCGGGCACACCACCTTCCTGGAGCT
GGCACCCAATCCGGTGGCGCTGATGCAGGTCGCCCTGACCACCGCCGATGCCGGGCTGCATGACGCCCAGTTGATCCCGA
CGCTGGCCCGCAAGCAAGACGAGGTCTCCTCGATGGTCTCGACCATGGCGCAGCTGTATGTGTACGGCCACGACCTGGAC
ATACGCACGCTGTTTAGCCGCGCCAGTGGGCCGCAGGATTACGCGAACATTCCGCCGACCCGGTTCAAGCGCAAGGAGCA
CTGGCTGCCCGCGCACTTCTCCGGCGACGGCTCGACGTACATGCCGGGCACCCATGTCGCCCTGCCGGATGGGCGGCACG
TCTGGGAGTACGCGCCGCGGGACGGCAATGTGGACTTGGCCGCGTTGGTCAGGGCCGCCGCCGCCCACGTGCTTCCGGAC
GCGCAACTGACCGCCGCCGAGCAGCGCGCGGTGCCCGGCGACGGCGCCCGGCTGGTGACGACGATGACCCGTCACCCCGG
CGGCGCCTCGGTGCAGGTGCACGCCCGCATCGACGAGTCCTTCACGCTGGTCTACGACGCCCTGGTGTCCCGAGCGGGGT
CCGAATCGGTGTTGCCCACCGCGGTGGGTGCGGCGACGGCGATCGCGGTTGCGGACGGGGCGCCTGTCGCGCCGGAAACG
CCCGCCGAAGACGCGGACGCCGAGACGCTTTCGGACAGCCTGACCACCCGTTACATGCCGTCCGGCATGACCCGATGGTC
GCCTGATTCCGGTGAGACCATCGCCGAGCGGCTGGGCCTGATTGTCGGGTCTGCGATGGGCTATGAGCCCGAGGACCTGC
CGTGGGAGGTGCCGCTGATCGAGCTTGGCCTGGACTCGCTGATGGCGGTGCGCATCAAAAACCGCGTCGAGTACGACTTC
GACCTGCCACCGATCCAGCTGACCGCGGTGCGCGACGCCAACCTCTACAACGTGGAGAAGCTGATCGAATACGCGGTCGA
GCACCGTGACGAGGTGCAGCAGCTGCACGAGCACCAGAAAACCCAGACCGCTGAGGAGATCGCGCGGGCCCAGGCCGAAT
TGCTGCATGGCAAGGTGGGCAAGACCGAGCCGGTCGACTCGGAAGCCGGGGTTGCGCTCCCGTCGCCGCAAAACGGCGAG
CAGCCAAACCCGACAGGGCCCGCGCTCAACGTCGACGTGCCGCCGCGGGACGCTGCCGAGCGGGTCACCTTCGCCACCTG
GGCGATCGTCACCGGCAAGTCCCCGGGCGGCATCTTCAACGAGCTGCCCAGGCTGGACGACGAGGCCGCGGCCAAGATTG
CGCAGCGGCTTTCCGAGCGCGCCGAAGGCCCGATCACCGCCGAGGACGTGCTGACGTCGTCGAACATCGAGGCGCTGGCC
GACAAGGTGCGCACGTATTTGGAGGCCGGGCAGATCGATGGGTTCGTCCGCACCCTGCGGGCGCGGCCCGAAGCAGGCGG
GAAGGTGCCGGTGTTCGTGTTTCATCCGGCCGGCGGCTCGACGGTGGTGTACGAGCCGCTGCTGGGCCGGCTGCCGGCGG
ACACCCCAATGTATGGCTTCGAACGGGTCGAGGGGTCGATCGAAGAGCGTGCACAGCAGTACGTGCCGAAGCTGATCGAG
ATGCAGGGCGACGGGCCCTATGTCCTGGTGGGTTGGTCGCTGGGCGGTGTGCTGGCCTACGCGTGCGCGATCGGTTTGCG
GCGGCTGGGCAAGGACGTGCGGTTCGTCGGGCTGATCGACGCGGTGCGCGCCGGTGAGGAGATCCCGCAGACCAAGGAGG
AGATCCGCAAGCGCTGGGACCGCTACGCCGCCTTCGCCGAGAAGACGTTCAACGTGACCATCCCGGCGATCCCGTACGAG
CAGCTCGAGGAGCTCGACGACGAGGGCCAGGTCCGGTTCGTGCTGGACGCCGTCAGCCAGTCCGGTGTGCAGATCCCGGC
CGGGATCATCGAACACCAACGCACGTCGTATCTGGACAACCGGGCGATCGACACCGCCCAGATCCAGCCGTACGACGGGC
ATGTCACCCTCTACATGGCCGATCGCTACCATGACGACGCGATCATGTTCGAGCCCCGCTACGCCGTGCGCCAGCCGGAC
GGCGGGTGGGGCGAGTACGTTTCCGACCTCGAGGTGGTGCCGATCGGTGGCGAGCACATTCAGGCCATCGACGAGCCGAT
CATCGCCAAGGTGGGCGAACACATGAGCCGCGCGTTGGGGCAGATCGAGGCCGATCGAACAAGTGAGGTAGGCAAGCAGT
GA

Upstream 100 bases:

>100_bases
CAAGATCGGCCGCCGCGCCTGCCGTGCGGCCTACCTCGACGGCAGCCTGCGCAGTGGCGTGGGTTCCCCGACGGTCTTCG
CCACTTCGGACTGAGGACCC

Downstream 100 bases:

>100_bases
CCGTCACCGAGCCGGTTCTGCATACCACCGCCGAGAAGCTGGCGGAGCTGCGCGAACGCCTGGAGTTGGCCAAGGAACCC
GGCGGTGAGAAGGCCGCCGC

Product: polyketide synthase Pks13

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1733; Mature: 1732

Protein sequence:

>1733_residues
MADVAESQENAPAERAELTVPEMRQWLRNWVGKAVGKAPDSIDESVPMVELGLSSRDAVAMAADIEDLTGVTLSVAVAFA
HPTIESLATRIIEGEPETDLAGDDAEDWSRTGPAERVDIAIVGLSTRFPGEMNTPEQTWQALLEGRDGITDLPDGRWSEF
LEEPRLAARVAGARTRGGYLKDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEHARIPASSLRGQAVGVYIGSSTN
DYSFLAVSDPTVAHPYAITGTSSSIIANRVSYFYDFHGPSVTIDTACSSSLVAIHQGVQALRNGEADVVVAGGVNALITP
MVTLGFDEIGAVLAPDGRIKSFSADADGYTRSEGGGMLVLKRVDDARRDGDAILAVIAGSAVNHDGRSNGLIAPNQDAQA
DVLRRAYKDAGIDPRTVDYIEAHGTGTILGDPIEAEALGRVVGRGRPADRPALLGAVKTNVGHLESAAGAASMAKVVLAL
QHDKLPPSINFAGPSPYIDFDAMRLKMITTPTDWPRYGGYALAGVSSFGFGGANAHVVVREVLPRDVVEKEPEPEPEPKA
AAEPAEAPTLAGHALRFDEFGNIITDSAVAEEPEPELPGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAA
AAELADWMQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQAPNVFSVDGPVTTGPVWVLAGFG
AQHRKMGKSLYLRNEVFAAWIEKVDALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPAAVIGQ
SLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGG
PPEQVDAILARAEAEGKFARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIKPGGEPIHDVEYWK
KGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQVALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLD
IRTLFSRASGPQDYANIPPTRFKRKEHWLPAHFSGDGSTYMPGTHVALPDGRHVWEYAPRDGNVDLAALVRAAAAHVLPD
AQLTAAEQRAVPGDGARLVTTMTRHPGGASVQVHARIDESFTLVYDALVSRAGSESVLPTAVGAATAIAVADGAPVAPET
PAEDADAETLSDSLTTRYMPSGMTRWSPDSGETIAERLGLIVGSAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDF
DLPPIQLTAVRDANLYNVEKLIEYAVEHRDEVQQLHEHQKTQTAEEIARAQAELLHGKVGKTEPVDSEAGVALPSPQNGE
QPNPTGPALNVDVPPRDAAERVTFATWAIVTGKSPGGIFNELPRLDDEAAAKIAQRLSERAEGPITAEDVLTSSNIEALA
DKVRTYLEAGQIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGFERVEGSIEERAQQYVPKLIE
MQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYE
QLEELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRQPD
GGWGEYVSDLEVVPIGGEHIQAIDEPIIAKVGEHMSRALGQIEADRTSEVGKQ

Sequences:

>Translated_1733_residues
MADVAESQENAPAERAELTVPEMRQWLRNWVGKAVGKAPDSIDESVPMVELGLSSRDAVAMAADIEDLTGVTLSVAVAFA
HPTIESLATRIIEGEPETDLAGDDAEDWSRTGPAERVDIAIVGLSTRFPGEMNTPEQTWQALLEGRDGITDLPDGRWSEF
LEEPRLAARVAGARTRGGYLKDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEHARIPASSLRGQAVGVYIGSSTN
DYSFLAVSDPTVAHPYAITGTSSSIIANRVSYFYDFHGPSVTIDTACSSSLVAIHQGVQALRNGEADVVVAGGVNALITP
MVTLGFDEIGAVLAPDGRIKSFSADADGYTRSEGGGMLVLKRVDDARRDGDAILAVIAGSAVNHDGRSNGLIAPNQDAQA
DVLRRAYKDAGIDPRTVDYIEAHGTGTILGDPIEAEALGRVVGRGRPADRPALLGAVKTNVGHLESAAGAASMAKVVLAL
QHDKLPPSINFAGPSPYIDFDAMRLKMITTPTDWPRYGGYALAGVSSFGFGGANAHVVVREVLPRDVVEKEPEPEPEPKA
AAEPAEAPTLAGHALRFDEFGNIITDSAVAEEPEPELPGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAA
AAELADWMQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQAPNVFSVDGPVTTGPVWVLAGFG
AQHRKMGKSLYLRNEVFAAWIEKVDALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPAAVIGQ
SLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGG
PPEQVDAILARAEAEGKFARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIKPGGEPIHDVEYWK
KGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQVALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLD
IRTLFSRASGPQDYANIPPTRFKRKEHWLPAHFSGDGSTYMPGTHVALPDGRHVWEYAPRDGNVDLAALVRAAAAHVLPD
AQLTAAEQRAVPGDGARLVTTMTRHPGGASVQVHARIDESFTLVYDALVSRAGSESVLPTAVGAATAIAVADGAPVAPET
PAEDADAETLSDSLTTRYMPSGMTRWSPDSGETIAERLGLIVGSAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDF
DLPPIQLTAVRDANLYNVEKLIEYAVEHRDEVQQLHEHQKTQTAEEIARAQAELLHGKVGKTEPVDSEAGVALPSPQNGE
QPNPTGPALNVDVPPRDAAERVTFATWAIVTGKSPGGIFNELPRLDDEAAAKIAQRLSERAEGPITAEDVLTSSNIEALA
DKVRTYLEAGQIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGFERVEGSIEERAQQYVPKLIE
MQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYE
QLEELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRQPD
GGWGEYVSDLEVVPIGGEHIQAIDEPIIAKVGEHMSRALGQIEADRTSEVGKQ
>Mature_1732_residues
ADVAESQENAPAERAELTVPEMRQWLRNWVGKAVGKAPDSIDESVPMVELGLSSRDAVAMAADIEDLTGVTLSVAVAFAH
PTIESLATRIIEGEPETDLAGDDAEDWSRTGPAERVDIAIVGLSTRFPGEMNTPEQTWQALLEGRDGITDLPDGRWSEFL
EEPRLAARVAGARTRGGYLKDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEHARIPASSLRGQAVGVYIGSSTND
YSFLAVSDPTVAHPYAITGTSSSIIANRVSYFYDFHGPSVTIDTACSSSLVAIHQGVQALRNGEADVVVAGGVNALITPM
VTLGFDEIGAVLAPDGRIKSFSADADGYTRSEGGGMLVLKRVDDARRDGDAILAVIAGSAVNHDGRSNGLIAPNQDAQAD
VLRRAYKDAGIDPRTVDYIEAHGTGTILGDPIEAEALGRVVGRGRPADRPALLGAVKTNVGHLESAAGAASMAKVVLALQ
HDKLPPSINFAGPSPYIDFDAMRLKMITTPTDWPRYGGYALAGVSSFGFGGANAHVVVREVLPRDVVEKEPEPEPEPKAA
AEPAEAPTLAGHALRFDEFGNIITDSAVAEEPEPELPGVTEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAA
AELADWMQSPEGQASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQAPNVFSVDGPVTTGPVWVLAGFGA
QHRKMGKSLYLRNEVFAAWIEKVDALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQIALGELLRHHGAKPAAVIGQS
LGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGP
PEQVDAILARAEAEGKFARKFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIKPGGEPIHDVEYWKK
GLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQVALTTADAGLHDAQLIPTLARKQDEVSSMVSTMAQLYVYGHDLDI
RTLFSRASGPQDYANIPPTRFKRKEHWLPAHFSGDGSTYMPGTHVALPDGRHVWEYAPRDGNVDLAALVRAAAAHVLPDA
QLTAAEQRAVPGDGARLVTTMTRHPGGASVQVHARIDESFTLVYDALVSRAGSESVLPTAVGAATAIAVADGAPVAPETP
AEDADAETLSDSLTTRYMPSGMTRWSPDSGETIAERLGLIVGSAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFD
LPPIQLTAVRDANLYNVEKLIEYAVEHRDEVQQLHEHQKTQTAEEIARAQAELLHGKVGKTEPVDSEAGVALPSPQNGEQ
PNPTGPALNVDVPPRDAAERVTFATWAIVTGKSPGGIFNELPRLDDEAAAKIAQRLSERAEGPITAEDVLTSSNIEALAD
KVRTYLEAGQIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGFERVEGSIEERAQQYVPKLIEM
QGDGPYVLVGWSLGGVLAYACAIGLRRLGKDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYEQ
LEELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRQPDG
GWGEYVSDLEVVPIGGEHIQAIDEPIIAKVGEHMSRALGQIEADRTSEVGKQ

Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=426, Percent_Identity=38.0281690140845, Blast_Score=291, Evalue=4e-78,
Organism=Homo sapiens, GI8923559, Length=436, Percent_Identity=28.2110091743119, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=33.5616438356164, Blast_Score=75, Evalue=6e-13,
Organism=Escherichia coli, GI1787337, Length=426, Percent_Identity=27.4647887323944, Blast_Score=137, Evalue=5e-33,
Organism=Escherichia coli, GI1788663, Length=293, Percent_Identity=30.7167235494881, Blast_Score=116, Evalue=1e-26,
Organism=Escherichia coli, GI1786801, Length=312, Percent_Identity=25.3205128205128, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=426, Percent_Identity=38.0281690140845, Blast_Score=290, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17550940, Length=552, Percent_Identity=31.1594202898551, Blast_Score=222, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71983541, Length=346, Percent_Identity=26.0115606936416, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=27.6515151515151, Blast_Score=104, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=26.4444444444444, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221330659, Length=448, Percent_Identity=37.7232142857143, Blast_Score=277, Evalue=4e-74,
Organism=Drosophila melanogaster, GI19920632, Length=448, Percent_Identity=37.7232142857143, Blast_Score=277, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24581345, Length=488, Percent_Identity=35.2459016393443, Blast_Score=269, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24644341, Length=448, Percent_Identity=28.5714285714286, Blast_Score=144, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 186447; Mature: 186316

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVAESQENAPAERAELTVPEMRQWLRNWVGKAVGKAPDSIDESVPMVELGLSSRDAVA
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCCCCCCEE
MAADIEDLTGVTLSVAVAFAHPTIESLATRIIEGEPETDLAGDDAEDWSRTGPAERVDIA
EEECHHHHCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEE
IVGLSTRFPGEMNTPEQTWQALLEGRDGITDLPDGRWSEFLEEPRLAARVAGARTRGGYL
EEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCH
KDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEHARIPASSLRGQAVGVYIGSSTN
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCC
DYSFLAVSDPTVAHPYAITGTSSSIIANRVSYFYDFHGPSVTIDTACSSSLVAIHQGVQA
CEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHHH
LRNGEADVVVAGGVNALITPMVTLGFDEIGAVLAPDGRIKSFSADADGYTRSEGGGMLVL
HHCCCCCEEEECCCHHHHHHHHHHCHHHHCCEECCCCCCEEECCCCCCCEECCCCCEEEE
KRVDDARRDGDAILAVIAGSAVNHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYI
EECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
EAHGTGTILGDPIEAEALGRVVGRGRPADRPALLGAVKTNVGHLESAAGAASMAKVVLAL
EECCCCCEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QHDKLPPSINFAGPSPYIDFDAMRLKMITTPTDWPRYGGYALAGVSSFGFGGANAHVVVR
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECHHHCCCCCCCHHHHHH
EVLPRDVVEKEPEPEPEPKAAAEPAEAPTLAGHALRFDEFGNIITDSAVAEEPEPELPGV
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHEEHHHHCCHHHCCHHCCCCCCCCCCC
TEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAAAELADWMQSPEGQASSLES
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQAPNVFSVDGPVTTGPVWVLAGFG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCC
AQHRKMGKSLYLRNEVFAAWIEKVDALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
IALGELLRHHGAKPAAVIGQSLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
YIRLMALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGPPEQVDAILARAEAEGKFAR
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHH
KFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIKPGGEPIHDVEYWK
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEECCCCCCCHHHHHHH
KGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQVALTTADAGLHDAQLIPTLARKQD
HHCCCCEEEHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EVSSMVSTMAQLYVYGHDLDIRTLFSRASGPQDYANIPPTRFKRKEHWLPAHFSGDGSTY
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCEE
MPGTHVALPDGRHVWEYAPRDGNVDLAALVRAAAAHVLPDAQLTAAEQRAVPGDGARLVT
CCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEE
TMTRHPGGASVQVHARIDESFTLVYDALVSRAGSESVLPTAVGAATAIAVADGAPVAPET
EEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCCCCCCC
PAEDADAETLSDSLTTRYMPSGMTRWSPDSGETIAERLGLIVGSAMGYEPEDLPWEVPLI
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ELGLDSLMAVRIKNRVEYDFDLPPIQLTAVRDANLYNVEKLIEYAVEHRDEVQQLHEHQK
HHCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQTAEEIARAQAELLHGKVGKTEPVDSEAGVALPSPQNGEQPNPTGPALNVDVPPRDAAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCHHH
RVTFATWAIVTGKSPGGIFNELPRLDDEAAAKIAQRLSERAEGPITAEDVLTSSNIEALA
HEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHH
DKVRTYLEAGQIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECHHHCCCCCCCCCHHH
ERVEGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDVRFVGLID
HHHCCHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEHHHHH
AVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYEQLEELDDEGQVRFVLDAVSQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCCCEEEEEEHHHC
SGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRQPD
CCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCEEEECCCHHCCCCC
GGWGEYVSDLEVVPIGGEHIQAIDEPIIAKVGEHMSRALGQIEADRTSEVGKQ
CCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure 
ADVAESQENAPAERAELTVPEMRQWLRNWVGKAVGKAPDSIDESVPMVELGLSSRDAVA
CCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCCCCCCEE
MAADIEDLTGVTLSVAVAFAHPTIESLATRIIEGEPETDLAGDDAEDWSRTGPAERVDIA
EEECHHHHCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEE
IVGLSTRFPGEMNTPEQTWQALLEGRDGITDLPDGRWSEFLEEPRLAARVAGARTRGGYL
EEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCH
KDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEHARIPASSLRGQAVGVYIGSSTN
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCC
DYSFLAVSDPTVAHPYAITGTSSSIIANRVSYFYDFHGPSVTIDTACSSSLVAIHQGVQA
CEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHHH
LRNGEADVVVAGGVNALITPMVTLGFDEIGAVLAPDGRIKSFSADADGYTRSEGGGMLVL
HHCCCCCEEEECCCHHHHHHHHHHCHHHHCCEECCCCCCEEECCCCCCCEECCCCCEEEE
KRVDDARRDGDAILAVIAGSAVNHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRTVDYI
EECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
EAHGTGTILGDPIEAEALGRVVGRGRPADRPALLGAVKTNVGHLESAAGAASMAKVVLAL
EECCCCCEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QHDKLPPSINFAGPSPYIDFDAMRLKMITTPTDWPRYGGYALAGVSSFGFGGANAHVVVR
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECHHHCCCCCCCHHHHHH
EVLPRDVVEKEPEPEPEPKAAAEPAEAPTLAGHALRFDEFGNIITDSAVAEEPEPELPGV
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHEEHHHHCCHHHCCHHCCCCCCCCCCC
TEEALRLKEAALEELAAQEVTAPLVPLAVSAFLTSRKKAAAAELADWMQSPEGQASSLES
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAAGKQAPNVFSVDGPVTTGPVWVLAGFG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCC
AQHRKMGKSLYLRNEVFAAWIEKVDALVQDELGYSVLELILDDAQDYGIETTQVTIFAIQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
IALGELLRHHGAKPAAVIGQSLGEAASAYFAGGLSLRDATRAICSRSHLMGEGEAMLFGE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
YIRLMALVEYSADEIREVFSDFPDLEVCVYAAPTQTVIGGPPEQVDAILARAEAEGKFAR
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHH
KFATKGASHTSQMDPLLGELTAELQGIKPTSPTCGIFSTVHEGRYIKPGGEPIHDVEYWK
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEECCCCCCCHHHHHHH
KGLRHSVYFTHGIRNAVDSGHTTFLELAPNPVALMQVALTTADAGLHDAQLIPTLARKQD
HHCCCCEEEHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EVSSMVSTMAQLYVYGHDLDIRTLFSRASGPQDYANIPPTRFKRKEHWLPAHFSGDGSTY
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCEE
MPGTHVALPDGRHVWEYAPRDGNVDLAALVRAAAAHVLPDAQLTAAEQRAVPGDGARLVT
CCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEE
TMTRHPGGASVQVHARIDESFTLVYDALVSRAGSESVLPTAVGAATAIAVADGAPVAPET
EEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCCCCCCC
PAEDADAETLSDSLTTRYMPSGMTRWSPDSGETIAERLGLIVGSAMGYEPEDLPWEVPLI
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ELGLDSLMAVRIKNRVEYDFDLPPIQLTAVRDANLYNVEKLIEYAVEHRDEVQQLHEHQK
HHCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQTAEEIARAQAELLHGKVGKTEPVDSEAGVALPSPQNGEQPNPTGPALNVDVPPRDAAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCHHH
RVTFATWAIVTGKSPGGIFNELPRLDDEAAAKIAQRLSERAEGPITAEDVLTSSNIEALA
HEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHH
DKVRTYLEAGQIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECHHHCCCCCCCCCHHH
ERVEGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDVRFVGLID
HHHCCHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEHHHHH
AVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYEQLEELDDEGQVRFVLDAVSQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCCCEEEEEEHHHC
SGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHVTLYMADRYHDDAIMFEPRYAVRQPD
CCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCEEEECCCHHCCCCC
GGWGEYVSDLEVVPIGGEHIQAIDEPIIAKVGEHMSRALGQIEADRTSEVGKQ
CCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]