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The map label for this gene is mec

Identifier: 148661123

GI number: 148661123

Start: 1503951

End: 1504391

Strand: Direct

Name: mec

Synonym: MRA_1342

Alternate gene names: 148661123

Gene position: 1503951-1504391 (Clockwise)

Preceding gene: 148661122

Following gene: 148661124

Centisome position: 34.03

GC content: 63.49

Gene sequence:

>441_bases
GTGTTGCTTAGGAAAGGAACCGTCTACGTGCTGGTGATTCGCGCAGACCTGGTGAATGCGATGGTGGCCCATGCGCGTCG
CGACCACCCCGACGAAGCCTGCGGAGTGCTGGCCGGACCCGAGGGCTCTGACCGTCCCGAGCGGCATATCCCGATGACCA
ATGCCGAGCGCTCGCCGACCTTCTACCGGTTGGATTCCGGTGAGCAACTGAAGGTGTGGCGGGCTATGGAAGATGCCGAC
GAGGTCCCGGTCGTCATCTATCACTCGCACACTGCGACCGAAGCGTACCCGAGCCGTACGGACGTGAAGCTTGCCACCGA
ACCCGACGCGCACTACGTGCTGGTGTCCACCCGCGACCCGCACCGGCACGAGCTACGCAGCTACCGCATCGTCGATGGCG
CTGTCACCGAGGAACCTGTCAATGTCGTCGAGCAGTACTGA

Upstream 100 bases:

>100_bases
GCTCGTGCGGTGCTGGCCGGCGTGCTCAATGCTCAGCCGGTAGCCGGAATACCGACCTACCGTGACATGTTTCCCGGAGC
ATTCGGGTCCTGAAACTTCG

Downstream 100 bases:

>100_bases
ACCGTTCCGAGAAAGGCCAGCATGAACGTCACCGTATCCATTCCGACCATCCTGCGGCCCCACACCGGCGGCCAGAAGAG
TGTCTCGGCCAGCGGCGATA

Product: hypothetical protein

Products: NA

Alternate protein names: Metallocarboxypeptidase Mec

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDAD
EVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY

Sequences:

>Translated_146_residues
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDAD
EVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY
>Mature_146_residues
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDAD
EVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY

Specific function: Protease that hydrolyzes the covalent CysO-cysteine adduct synthesized by CysM to release L-cysteine and regenerate CysO

COG id: COG1310

COG function: function code R; Predicted metal-dependent protease of the PAD1/JAB1 superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MPN (JAB/Mov34) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MEC_MYCBO (P64814)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_855023.1
- ProteinModelPortal:   P64814
- EnsemblBacteria:   EBMYCT00000017122
- GeneID:   1090660
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1369
- GeneTree:   EBGT00050000017583
- HOGENOM:   HBG712429
- OMA:   EPVVIYH
- ProtClustDB:   CLSK871927
- BioCyc:   MBOV233413:MB1369-MONOMER
- InterPro:   IPR000555
- SMART:   SM00232

Pfam domain/function: PF01398 Mov34

EC number: NA

Molecular weight: Translated: 16530; Mature: 16530

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPT
CEECCCCEEEEEEHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCCCCCCCCCCCE
FYRLDSGEQLKVWRAMEDADEVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDP
EEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
HRHELRSYRIVDGAVTEEPVNVVEQY
CHHHHHEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPT
CEECCCCEEEEEEHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCCCCCCCCCCCE
FYRLDSGEQLKVWRAMEDADEVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDP
EEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
HRHELRSYRIVDGAVTEEPVNVVEQY
CHHHHHEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972