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The map label for this gene is 148661122

Identifier: 148661122

GI number: 148661122

Start: 1502909

End: 1503943

Strand: Direct

Name: 148661122

Synonym: MRA_1341

Alternate gene names: NA

Gene position: 1502909-1503943 (Clockwise)

Preceding gene: 148661121

Following gene: 148661123

Centisome position: 34.0

GC content: 69.95

Gene sequence:

>1035_bases
ATGAACTCCATCACCGACGTCGGGGGCATCCGGGTTGGCCACTACCAGAGACTGGACCCCGACGCGTCCCTCGGCGCCGG
GTGGGCTTGTGGCGTCACGGTGGTGTTGCCGCCGCCCGGGACGGTCGGTGCGGTCGATTGCCGCGGCGGCGCCCCTGGAA
CCCGCGAGACTGATCTGCTGGACCCGGCCAACAGCGTGCGCTTCGTCGACGCCCTGTTGCTCGCCGGCGGCAGCGCCTAC
GGTCTGGCCGCCGCCGATGGCGTCATGCGCTGGCTAGAGGAACACCGGCGCGGCGTCGCGATGGACAGCGGCGTGGTGCC
CATCGTGCCGGGCGCGGTGATTTTCGACCTTCCGGTCGGCGGCTGGAATTGTCGGCCGACGGCCGATTTCGGCTATTCGG
CCTGTGCGGCAGCCGGAGTCGACGTCGCGGTCGGGACGGTGGGCGTGGGGGTTGGGGCGCGCGCCGGAGCGCTCAAGGGC
GGTGTCGGGACTGCATCGGCTACCCTGCAGTCCGGTGTGACCGTCGGTGTCCTTGCTGTGGTAAATGCCGCTGGCAACGT
CGTCGATCCAGCCACCGGCTTGCCGTGGATGGCCGACCTAGTCGGCGAGTTCGCGTTGAGGGCCCCGCCGGCCGAGCAGA
TTGCTGCGCTGGCGCAGTTATCGTCCCCGCTGGGAGCCTTCAACACCCCGTTCAATACGACGATCGGTGTGATTGCGTGT
GACGCCGCGCTGAGCCCTGCGGCTTGCCGGCGCATCGCGATTGCCGCCCACGACGGGTTGGCCCGCACCATCCGGCCGGC
ACACACCCCCTTGGATGGCGACACGGTTTTCGCGCTGGCCACCGGCGCGGTAGCGGTGCCGCCGGAGGCCGGCGTGCCGG
CCGCATTGTCTCCGGAGACTCAGCTGGTCACCGCGGTCGGTGCGGCGGCGGCTGATTGCCTGGCTCGTGCGGTGCTGGCC
GGCGTGCTCAATGCTCAGCCGGTAGCCGGAATACCGACCTACCGTGACATGTTTCCCGGAGCATTCGGGTCCTGA

Upstream 100 bases:

>100_bases
CCGTTGGCCGCGCACTTCAATGTCTACCAGTGGCTGACAGTCCTGCAGGAATACCTCGTGCTGGTGCTGATGGGGTCTCG
ATGATCTGCGCGGCGGCCCG

Downstream 100 bases:

>100_bases
AACTTCGGTGTTGCTTAGGAAAGGAACCGTCTACGTGCTGGTGATTCGCGCAGACCTGGTGAATGCGATGGTGGCCCATG
CGCGTCGCGACCACCCCGAC

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPANSVRFVDALLLAGGSAY
GLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVGGWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKG
GVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIAC
DAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPETQLVTAVGAAAADCLARAVLA
GVLNAQPVAGIPTYRDMFPGAFGS

Sequences:

>Translated_344_residues
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPANSVRFVDALLLAGGSAY
GLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVGGWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKG
GVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIAC
DAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPETQLVTAVGAAAADCLARAVLA
GVLNAQPVAGIPTYRDMFPGAFGS
>Mature_344_residues
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPANSVRFVDALLLAGGSAY
GLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVGGWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKG
GVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIAC
DAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPETQLVTAVGAAAADCLARAVLA
GVLNAQPVAGIPTYRDMFPGAFGS

Specific function: Unknown

COG id: COG3191

COG function: function code EQ; L-aminopeptidase/D-esterase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1167

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1333_MYCTU (P64811)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   A70771
- RefSeq:   NP_215849.1
- RefSeq:   NP_335825.1
- ProteinModelPortal:   P64811
- EnsemblBacteria:   EBMYCT00000001149
- EnsemblBacteria:   EBMYCT00000071166
- GeneID:   886882
- GeneID:   924679
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1375
- KEGG:   mtu:Rv1333
- TIGR:   MT1375
- TubercuList:   Rv1333
- GeneTree:   EBGT00050000016187
- HOGENOM:   HBG759105
- OMA:   FDLLNGG
- ProtClustDB:   CLSK791103
- InterPro:   IPR016117
- InterPro:   IPR005321
- Gene3D:   G3DSA:3.60.70.12

Pfam domain/function: PF03576 Peptidase_S58; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: NA

Molecular weight: Translated: 33953; Mature: 33953

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b884ee0)-; HASH(0x1e371278)-; HASH(0x1c9e7dc4)-; HASH(0x1c097308)-; HASH(0x1b0236b8)-; HASH(0x1dc7dd10)-; HASH(0x1dda2170)-; HASH(0x1b0e1588)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLL
CCCCCCCCCEEECCCCCCCCCCCCCCCEECCEEEEECCCCCEEEEECCCCCCCCCCCCCC
DPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVG
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCC
GWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKGGVGTASATLQSGVTVGVLAV
CCCCCCCCCCCCHHHHHCCCCEEEHEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
VNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIAC
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
DAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPET
CCCCCHHHHHEEEEEECCCHHHHCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCH
QLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYRDMFPGAFGS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCH
>Mature Secondary Structure
MNSITDVGGIRVGHYQRLDPDASLGAGWACGVTVVLPPPGTVGAVDCRGGAPGTRETDLL
CCCCCCCCCEEECCCCCCCCCCCCCCCEECCEEEEECCCCCEEEEECCCCCCCCCCCCCC
DPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAVIFDLPVG
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCC
GWNCRPTADFGYSACAAAGVDVAVGTVGVGVGARAGALKGGVGTASATLQSGVTVGVLAV
CCCCCCCCCCCCHHHHHCCCCEEEHEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
VNAAGNVVDPATGLPWMADLVGEFALRAPPAEQIAALAQLSSPLGAFNTPFNTTIGVIAC
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
DAALSPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAVAVPPEAGVPAALSPET
CCCCCHHHHHEEEEEECCCHHHHCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCH
QLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYRDMFPGAFGS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036