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The map label for this gene is atsA [H]

Identifier: 148660486

GI number: 148660486

Start: 807641

End: 810004

Strand: Direct

Name: atsA [H]

Synonym: MRA_0719

Alternate gene names: 148660486

Gene position: 807641-810004 (Clockwise)

Preceding gene: 148660485

Following gene: 148660487

Centisome position: 18.27

GC content: 63.03

Gene sequence:

>2364_bases
ATGGCACCCGAGGCCACCGAGGCGTTCAACGGCACCATCGAGCTGGATATTCGTGATTCGGAGCCGGATTGGGGCCCATA
CGCAGCGCCGGTGGCACCGGAGCACTCACCAAACATCCTGTATCTGGTCTGGGACGACGTCGGCATCGCGACCTGGGACT
GCTTTGGCGGCCTGGTCGAGATGCCCGCGATGACGCGCGTCGCCGAGCGTGGCGTGCGACTGTCGCAATTTCACACCACC
GCACTGTGCTCGCCGACCCGGGCGTCGCTGCTGACCGGTCGCAACGCCACCACCGTAGGCATGGCTACCATCGAAGAGTT
CACCGACGGGTTCCCCAACTGCAACGGGCGGATCCCGGCTGACACCGCGTTGCTCCCAGAGGTGCTGGCCGAACATGGCT
ACAACACCTACTGTGTGGGCAAGTGGCACCTGACGCCACTCGAAGAATCCAATATGGCGTCGACGAAGCGGCACTGGCCG
ACCTCGCGTGGGTTCGAGCGGTTCTACGGATTCCTAGGCGGGGAGACCGACCAGTGGTATCCCGACCTGGTATACGACAA
CCACCCAGTGAGTCCTCCCGGCACACCCGAGGGTGGCTACCACCTGTCAAAAGACATCGCCGACAAGACGATCGAGTTCA
TTCGTGATGCCAAGGTGATCGCGCCCGACAAGCCGTGGTTCAGCTACGTGTGCCCAGGCGCCGGGCATGCGCCGCACCAC
GTCTTCAAGGAATGGGCGGACAGATACGCCGGCCGATTCGACATGGGGTATGAGCGCTATCGCGAGATCGTGCTGGAAAG
GCAAAAGGCGCTAGGGATCGTGCCACCCGACACCGAACTGTCGCCCATAAACCCTTATCTGGATGTGCCGGGGCCAAACG
GCGAGACCTGGCCGCTGCAGGACACGGTGCGGCCGTGGGACTCGCTGAGCGATGAAGAAAAGAAGCTGTTTTGCCGGATG
GCCGAGGTGTTCGCCGGCTTTCTGAGCTACACCGACGCCCAGATCGGACGGATCCTGGACTACCTCGAGGAATCCGGCCA
GCTGGACAACACCATCATCGTGGTGATCTCCGACAACGGCGCCAGCGGCGAGGGCGGACCCAACGGATCGGTCAACGAAG
GCAAGTTCTTCAACGGCTACATCGACACCGTCGCTGAAAGCATGAAGCTCTTCGACCACCTCGGTGGCCCGCAGACCTAC
AACCACTACCCCATCGGGTGGGCAATGGCCTTCAACACCCCCTACAAGCTGTTCAAGCGCTACGCCTCGCATGAAGGCGG
CATTGCCGACCCGGCAATCATCTCCTGGCCCAACGGCATTGCCGCACACGGTGAAATCCGCGACAACTACGTCAATGTCA
GCGACATCACGCCCACCGTCTACGACCTGTTGGGCATGACACCGCCGGGGACCGTCAAGGGGATTCCGCAGAAACCGATG
GACGGCGTGAGCTTCATAGCGGCCCTTGCCGACCCGGCCGCCGACACCGGCAAGACCACCCAGTTCTACACCATGCTGGG
CACCCGCGGGATCTGGCATGAAGGTTGGTTCGCCAACACCATTCACGCGGCCACGCCCGCCGGCTGGTCGAATTTCAACG
CTGACCGCTGGGAACTGTTCCACATCGCAGCAGACCGCAGCCAGTGCCACGACCTGGCCGCCGAGCATCCCGACAAACTT
GAGGAGCTCAAGGCGCTGTGGTTCTCCGAAGCCGCCAAGTACAACGGGCTGCCGCTGGCCGATCTGAACCTCCTGGAAAC
GATGACTCGGTCGCGGCCTTACCTGGTCAGCGAACGAGCCAGCTACGTCTACTATCCCGACTGCGCTGACGTCGGCATCG
GCGCGGCCGTAGAGATTCGCGGGCGCTCGTTCGCCGTGCTGGCCGATGTGACCATCGATACCACCGGCGCCGAGGGCGTG
CTGTTCAAGCACGGCGGCGCCCATGGCGGGCACGTGCTGTTCGTCCGGGACGGACGCTTGCACTACGTCTACAACTTCCT
CGGTGAGCGCCAGCAGCTGGTCAGCTCGTCGGGTCCGGTCCCGTCGGGAAGACATCTACTCGGGGTTCGTTATTTGCGGA
CCGGAACCGTGCCCAACAGTCACACGCCGGTGGGCGATCTTGAGCTGTTCTTCGACGAGAACCTGGTCGGCGCCCTGACC
AATGTGCTGACCCACCCTGGAACGTTCGGGTTGGCCGGCGCCGCTATCAGCGTTGGCCGCAACGGCGGTTCGGCTGTGTC
CAGCCACTACGAAGCGCCGTTCGCGTTCACCGGCGGTACCATCACCCAGGTCACCGTCGACGTGTCAGGCCGACCGTTCG
AAGATGTGGAATCCGATCTTGCGCTTGCTTTTTCGCGTGACTGA

Upstream 100 bases:

>100_bases
ACCAGCGCGGCGTCAGTGCGGAAATCCTCAGCTGATTCCTACCCTGTGCGTGTAGTGTACACAACCGTTCATTAACTCCA
CGGGGAAGTGAGGCTGGCTT

Downstream 100 bases:

>100_bases
GCGGTCTGCTGTGACGCGGGACGGCGTGGTCGGCATACGCTGAAGTCGTGCTGACCGAGTTGGTTGACCTGCCCGGCGGA
TCGTTCCGCATGGGCTCGAC

Product: putative arylsulfatase AtsA

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MAPEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVEMPAMTRVAERGVRLSQFHTT
ALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPADTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWP
TSRGFERFYGFLGGETDQWYPDLVYDNHPVSPPGTPEGGYHLSKDIADKTIEFIRDAKVIAPDKPWFSYVCPGAGHAPHH
VFKEWADRYAGRFDMGYERYREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQDTVRPWDSLSDEEKKLFCRM
AEVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVISDNGASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTY
NHYPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGIAAHGEIRDNYVNVSDITPTVYDLLGMTPPGTVKGIPQKPM
DGVSFIAALADPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWSNFNADRWELFHIAADRSQCHDLAAEHPDKL
EELKALWFSEAAKYNGLPLADLNLLETMTRSRPYLVSERASYVYYPDCADVGIGAAVEIRGRSFAVLADVTIDTTGAEGV
LFKHGGAHGGHVLFVRDGRLHYVYNFLGERQQLVSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALT
NVLTHPGTFGLAGAAISVGRNGGSAVSSHYEAPFAFTGGTITQVTVDVSGRPFEDVESDLALAFSRD

Sequences:

>Translated_787_residues
MAPEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVEMPAMTRVAERGVRLSQFHTT
ALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPADTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWP
TSRGFERFYGFLGGETDQWYPDLVYDNHPVSPPGTPEGGYHLSKDIADKTIEFIRDAKVIAPDKPWFSYVCPGAGHAPHH
VFKEWADRYAGRFDMGYERYREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQDTVRPWDSLSDEEKKLFCRM
AEVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVISDNGASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTY
NHYPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGIAAHGEIRDNYVNVSDITPTVYDLLGMTPPGTVKGIPQKPM
DGVSFIAALADPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWSNFNADRWELFHIAADRSQCHDLAAEHPDKL
EELKALWFSEAAKYNGLPLADLNLLETMTRSRPYLVSERASYVYYPDCADVGIGAAVEIRGRSFAVLADVTIDTTGAEGV
LFKHGGAHGGHVLFVRDGRLHYVYNFLGERQQLVSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALT
NVLTHPGTFGLAGAAISVGRNGGSAVSSHYEAPFAFTGGTITQVTVDVSGRPFEDVESDLALAFSRD
>Mature_786_residues
APEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVEMPAMTRVAERGVRLSQFHTTA
LCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPADTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWPT
SRGFERFYGFLGGETDQWYPDLVYDNHPVSPPGTPEGGYHLSKDIADKTIEFIRDAKVIAPDKPWFSYVCPGAGHAPHHV
FKEWADRYAGRFDMGYERYREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQDTVRPWDSLSDEEKKLFCRMA
EVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVISDNGASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTYN
HYPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGIAAHGEIRDNYVNVSDITPTVYDLLGMTPPGTVKGIPQKPMD
GVSFIAALADPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWSNFNADRWELFHIAADRSQCHDLAAEHPDKLE
ELKALWFSEAAKYNGLPLADLNLLETMTRSRPYLVSERASYVYYPDCADVGIGAAVEIRGRSFAVLADVTIDTTGAEGVL
FKHGGAHGGHVLFVRDGRLHYVYNFLGERQQLVSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALTN
VLTHPGTFGLAGAAISVGRNGGSAVSSHYEAPFAFTGGTITQVTVDVSGRPFEDVESDLALAFSRD

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI59797060, Length=244, Percent_Identity=29.9180327868852, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI109389362, Length=253, Percent_Identity=27.6679841897233, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI38569407, Length=247, Percent_Identity=28.7449392712551, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI38569405, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI157266309, Length=161, Percent_Identity=37.2670807453416, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI71852584, Length=141, Percent_Identity=36.1702127659575, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI71852586, Length=146, Percent_Identity=35.6164383561644, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI53831991, Length=137, Percent_Identity=34.3065693430657, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI58743319, Length=140, Percent_Identity=35.7142857142857, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI31742482, Length=151, Percent_Identity=33.112582781457, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI4503899, Length=258, Percent_Identity=28.2945736434109, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI146229331, Length=137, Percent_Identity=33.5766423357664, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI146229329, Length=137, Percent_Identity=33.5766423357664, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI6005990, Length=137, Percent_Identity=33.5766423357664, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI146229324, Length=137, Percent_Identity=33.5766423357664, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI87081924, Length=213, Percent_Identity=26.7605633802817, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533416, Length=338, Percent_Identity=24.8520710059172, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17559078, Length=141, Percent_Identity=35.4609929078014, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281363223, Length=353, Percent_Identity=24.3626062322946, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24666175, Length=328, Percent_Identity=25.609756097561, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24666109, Length=436, Percent_Identity=23.8532110091743, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281366397, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281366395, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666163, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 86215; Mature: 86084

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2 ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVE
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHH
MPAMTRVAERGVRLSQFHTTALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPA
HHHHHHHHHCCCEEHHHHHHHHCCCCHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCCC
DTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWPTSRGFERFYGFLGGETDQWY
CHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCC
PDLVYDNHPVSPPGTPEGGYHLSKDIADKTIEFIRDAKVIAPDKPWFSYVCPGAGHAPHH
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEECCCCCCCHHH
VFKEWADRYAGRFDMGYERYREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
DTVRPWDSLSDEEKKLFCRMAEVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVISDNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
ASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTYNHYPIGWAMAFNTPYKLFKR
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHH
YASHEGGIADPAIISWPNGIAAHGEIRDNYVNVSDITPTVYDLLGMTPPGTVKGIPQKPM
HHCCCCCCCCCCEEECCCCCEECCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCC
DGVSFIAALADPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWSNFNADRWELF
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEE
HIAADRSQCHDLAAEHPDKLEELKALWFSEAAKYNGLPLADLNLLETMTRSRPYLVSERA
EEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCC
SYVYYPDCADVGIGAAVEIRGRSFAVLADVTIDTTGAEGVLFKHGGAHGGHVLFVRDGRL
CEEECCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCE
HYVYNFLGERQQLVSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALT
EEHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHH
NVLTHPGTFGLAGAAISVGRNGGSAVSSHYEAPFAFTGGTITQVTVDVSGRPFEDVESDL
HHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEECCCEEEEEEEEECCCCHHHHHHHH
ALAFSRD
EEEEECC
>Mature Secondary Structure 
APEATEAFNGTIELDIRDSEPDWGPYAAPVAPEHSPNILYLVWDDVGIATWDCFGGLVE
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHH
MPAMTRVAERGVRLSQFHTTALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPA
HHHHHHHHHCCCEEHHHHHHHHCCCCHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCCC
DTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWPTSRGFERFYGFLGGETDQWY
CHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCC
PDLVYDNHPVSPPGTPEGGYHLSKDIADKTIEFIRDAKVIAPDKPWFSYVCPGAGHAPHH
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEECCCCCCCHHH
VFKEWADRYAGRFDMGYERYREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
DTVRPWDSLSDEEKKLFCRMAEVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVISDNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
ASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTYNHYPIGWAMAFNTPYKLFKR
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHH
YASHEGGIADPAIISWPNGIAAHGEIRDNYVNVSDITPTVYDLLGMTPPGTVKGIPQKPM
HHCCCCCCCCCCEEECCCCCEECCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCC
DGVSFIAALADPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWSNFNADRWELF
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEE
HIAADRSQCHDLAAEHPDKLEELKALWFSEAAKYNGLPLADLNLLETMTRSRPYLVSERA
EEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCC
SYVYYPDCADVGIGAAVEIRGRSFAVLADVTIDTTGAEGVLFKHGGAHGGHVLFVRDGRL
CEEECCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCE
HYVYNFLGERQQLVSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALT
EEHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHH
NVLTHPGTFGLAGAAISVGRNGGSAVSSHYEAPFAFTGGTITQVTVDVSGRPFEDVESDL
HHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEECCCEEEEEEEEECCCCHHHHHHHH
ALAFSRD
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]