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The map label for this gene is nagC [C]

Identifier: 148660252

GI number: 148660252

Start: 575294

End: 576610

Strand: Direct

Name: nagC [C]

Synonym: MRA_0492

Alternate gene names: 148660252

Gene position: 575294-576610 (Clockwise)

Preceding gene: 148660250

Following gene: 148660253

Centisome position: 13.02

GC content: 68.72

Gene sequence:

>1317_bases
GTGTACTCGACTAACCGCACCTCACAGTCACTCAGCCGCAAGCCCGGCCGCAAGCACCAGCTGCGATCGCACCGTTACGT
CATGCCGCCGTCGCTGCACCTGTCCGATTCCGCGGCTGCGTCCGTCTTCCGGGCCGTGCGTTTGCGTGGTCCGGTCGGTC
GGGACGTAATTGCTGGATCTACGTCGCTGAGCATCGCGACGGTGAACCGCCAGGTCATCGCACTGCTGGAAGCGGGCCTC
CTGCGTGAGCGGGCGGACCTGGCGGTTTCCGGGGCTATCGGGCGCCCACGCGTGCCTGTCGAAGTAAACCACGAGCCTTT
TGTCACCCTGGGCATCCACATCGGTGCCCGGACCACCAGCATCGTGGCCACCGACCTGTTCGGCCGCACGCTCGACACGG
TGGAGACCCCGACCCCGCGTAACGCTGCCGGGGCCGCGCTGACCTCACTGGCCGACAGCGCTGACCGATACTTGCAGCGC
TGGCGCCGGCGCCGTGCGCTGTGGGTCGGGGTGACGCTTGGTGGTGCAGTCGACAGTGCCACCGGTCATGTCGACCATCC
GCGGCTCGGTTGGCGTCAGGCTCCGGTCGGACCCGTGCTGGCGGATGCCCTAGGCCTGCCCGTGTCGGTGGCGTCCCACG
TCGACGCCATGGCCGGGGCCGAGCTGATGCTCGGCATGCGGCGGTTCGCACCGAGCTCGTCGACGAGCCTCTACGTCTAC
GCCCGCGAAACCGTAGGCTATGCGCTGATGATCGGTGGGCGGGTGCACTGCCCGGCCAGTGGTCCCGGCACCATCGCGCC
CCTGCCCGTCCACTCTGAAATGCTCGGCGGTACCGGGCAGCTGGAGTCCACTGTCAGCGACGAGGCGGTTTTGGCTGCTG
CCCGCCGGCTGCGGATCATCCCCGGCATCGCTTCGAGGACCCGGACCGGTGGGTCCGCTACCGCCATCACCGACTTGCTG
CGAGTGGCACGAGCCGGTAATCAGCAAGCCAAGGAGCTGCTGGCGGAGCGGGCCCGCGTGCTCGGTGGGGCGGTCGCGCT
GCTGCGTGACTTACTCAATCCCGACGAAGTGGTGGTGGGTGGCCAGGCGTTTACCGAATATCCCGAGGCGATGGAGCAGG
TGGAGGCGGCGTTTACGGCAGGGTCGGTGCTGGCGCCGCGTGACATCCGCGTGACCGTTTTCGGCAACCGGGTGCAGGAG
GCCGGGGCAGGCATCGTGTCCCTAAGCGGGCTCTATGCCGATCCATTGGGTGCCTTGCGGCGATCGGGCGCGCTGGATGC
CCGGCTGCAGGACACCGCCCCGGAGGCGCTCGCGTGA

Upstream 100 bases:

>100_bases
GGGCGCGTGTTGTTGCCGCCCCCTTTGCCGCGCCTGACCGATACACGTCAGCAGGTGTGGCCAACAGGACCCGGCCATTG
GAACTCGGAGAAGAACGCCC

Downstream 100 bases:

>100_bases
TCGGCTGACGAGCCGCGTCCGCGCGTGTCACTTCGGTTCCTGCAAGGATGGCAGGTGTGCGGCACGATGACGGTTCAGGG
TTGATCGCCCAGCGCCGTCC

Product: NagC-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGL
LRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQR
WRRRRALWVGVTLGGAVDSATGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVY
ARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLL
RVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQE
AGAGIVSLSGLYADPLGALRRSGALDARLQDTAPEALA

Sequences:

>Translated_438_residues
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGL
LRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQR
WRRRRALWVGVTLGGAVDSATGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVY
ARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLL
RVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQE
AGAGIVSLSGLYADPLGALRRSGALDARLQDTAPEALA
>Mature_438_residues
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGL
LRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQR
WRRRRALWVGVTLGGAVDSATGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVY
ARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLL
RVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQE
AGAGIVSLSGLYADPLGALRRSGALDARLQDTAPEALA

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786891, Length=332, Percent_Identity=22.8915662650602, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787878, Length=341, Percent_Identity=22.8739002932551, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y485_MYCTU (P64705)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   H70743
- RefSeq:   NP_214999.1
- RefSeq:   NP_334912.1
- ProteinModelPortal:   P64705
- SMR:   P64705
- EnsemblBacteria:   EBMYCT00000002554
- EnsemblBacteria:   EBMYCT00000072073
- GeneID:   887170
- GeneID:   923859
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0503
- KEGG:   mtu:Rv0485
- TIGR:   MT0503
- TubercuList:   Rv0485
- GeneTree:   EBGT00050000016471
- HOGENOM:   HBG564996
- OMA:   FTEYPEG
- ProtClustDB:   CLSK790549
- InterPro:   IPR000600

Pfam domain/function: PF00480 ROK

EC number: NA

Molecular weight: Translated: 46099; Mature: 46099

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGS
CCCCCCCHHHHHCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCC
TSLSIATVNRQVIALLEAGLLRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTS
CEEEEEEHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEECCCCEEEEEEEECCCCHH
IVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQRWRRRRALWVGVTLGGAVDSA
HHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC
TGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVY
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRII
EECCCCEEEEECCEEECCCCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PGIASRTRTGGSATAITDLLRVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVG
CCCHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
GQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALR
CHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCHHHHHCCCEEEECCCCCCHHHHHH
RSGALDARLQDTAPEALA
HCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGS
CCCCCCCHHHHHCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCC
TSLSIATVNRQVIALLEAGLLRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTS
CEEEEEEHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEECCCCEEEEEEEECCCCHH
IVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQRWRRRRALWVGVTLGGAVDSA
HHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC
TGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVY
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRII
EECCCCEEEEECCEEECCCCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PGIASRTRTGGSATAITDLLRVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVG
CCCHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
GQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALR
CHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCHHHHHCCCEEEECCCCCCHHHHHH
RSGALDARLQDTAPEALA
HCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036