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The map label for this gene is 148659803

Identifier: 148659803

GI number: 148659803

Start: 48724

End: 49458

Strand: Reverse

Name: 148659803

Synonym: MRA_0046

Alternate gene names: NA

Gene position: 49458-48724 (Counterclockwise)

Preceding gene: 148659804

Following gene: 148659802

Centisome position: 1.12

GC content: 63.67

Gene sequence:

>735_bases
ATGCCAAAAAAGTACGGGGTTAAGGAAAAGGACCAGGTTGTCGCCCACATCCTCAACCTGCTATTGACCGGCAAACTGCG
CAGCGGGGACCGCGTCGACCGCAATGAAATCGCGCACGGCCTGGGGGTCAGCCGGGTTCCCATCCAAGAGGCGCTGGTTC
AACTCGAACACGACGGCATTGTGTCGACTCGCTATCACCGCGGCGCGTTCATCGAGCGGTTCGACGTCGCCACCATCCTG
GAACATCACGAACTCGACGGCTTGCTCAACGGCATTGCCTCTGCCCGCGCAGCCGCCAACCCCACGCCTCGGATCCTGGG
CCAGCTCGACGCAGTCATGCGATCGCTGCGCAACTCCAAGGAGTCGCGGGCCTTCGCCGAATGCGTGTGGGAGTACCGGC
GCACGGTCAACGACGAGTACGCAGGACCGCGGCTGCACGCCACCATCCGGGCCTCACAGAACCTGATTCCGCGAGTGTTC
TGGATGACATACCAAAACAGCCGCGACGACGTGTTGCCGTTCTACGAGGAAGAGAACGCCGCAATCCATCGGCGCGAACC
TGAAGCTGCGAGGGCTGCCTGCATCGGCCGTTCCGAGCTGATGGCCCAGACGATGCTGGCCGAACTGTTCCGCCGCCGAG
TATTGGTCCCGCCCGAGGGCGCTTGTCCCGGCCCGTTTGGGGCGCCGATCCCTGGCTTCGCCAGAAGCTACCAGCCCTCC
TCACCGGTGCCCTAA

Upstream 100 bases:

>100_bases
CCCGGCTTCATCTGGGAAACACCACAACGCAGACGCCGAGTCATGAGAAACTTGCCAGCGCCGGATGGCTGCAGCGGGCT
GAAAGAGATGCTAGATACCG

Downstream 100 bases:

>100_bases
TTACGCCGATCCGATGGTGAAGCCAGCAGCGGCTGCCGGCGTCTCCAATATTGACTGTCCCGTTAACGCGAGAGCCGGTT
TCCGTTGGCGGTCAGTGGCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATIL
EHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVF
WMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPS
SPVP

Sequences:

>Translated_244_residues
MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATIL
EHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVF
WMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPS
SPVP
>Mature_243_residues
PKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILE
HHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVFW
MTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPSS
PVP

Specific function: Unknown

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y043_MYCTU (P67737)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   C70912
- RefSeq:   NP_214557.1
- RefSeq:   NP_334457.1
- ProteinModelPortal:   P67737
- EnsemblBacteria:   EBMYCT00000003564
- EnsemblBacteria:   EBMYCT00000069209
- GeneID:   887032
- GeneID:   922642
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0049
- KEGG:   mtu:Rv0043c
- TIGR:   MT0049
- TubercuList:   Rv0043c
- GeneTree:   EBGT00050000014630
- HOGENOM:   HBG568447
- OMA:   TINEEYA
- ProtClustDB:   CLSK871748
- GO:   GO:0005622
- InterPro:   IPR000524
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00345

Pfam domain/function: PF00392 GntR

EC number: NA

Molecular weight: Translated: 27329; Mature: 27197

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
VSTRYHRGAFIERFDVATILEHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSK
EECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH
ESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENA
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHEEEEECCCCCCCCCCCCCCCC
AIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
SPVP
CCCC
>Mature Secondary Structure 
PKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
VSTRYHRGAFIERFDVATILEHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSK
EECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH
ESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENA
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHEEEEECCCCCCCCCCCCCCCC
AIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
SPVP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036