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The map label for this gene is udg [H]

Identifier: 148652085

GI number: 148652085

Start: 324762

End: 326102

Strand: Direct

Name: udg [H]

Synonym: PsycPRwf_0273

Alternate gene names: 148652085

Gene position: 324762-326102 (Clockwise)

Preceding gene: 148652084

Following gene: 148652088

Centisome position: 10.9

GC content: 48.99

Gene sequence:

>1341_bases
ATGGCAACGTCAACTCATTCGCCTGCTGCCCCTAGCAAAGCTGTTACCGACCACTGCGTTATTGTGGGTCATTCTATCGA
TGCCATCACCACCGCGACAGTCATGGTCAGTCTTGGCAATCAGGTGTGCCTGTATGCAGACCAACAAGCCTTGCAGCATA
CGCTTGAGACTTACACCTTTGAGCATCAACAGCAAGCGCTATGGCAGCTGTATCTCAATCAAAACAGCATTGTTGTGCAG
GACATGCCACAGCTTGCAAGCCAATTATTTAGCAATACTAAGGCCAGCTTCTACTGGCTGTTTTATGGCGATTTGCCCAG
CAGCTGGCAAGCTTTGGATGGGGTGCAGCAAGCATGGGTCAGTGAGCTGAATGACAGCCAAGTACCCAGTCAGACGCCAG
TTATTTTCAGTGGTATCAGCACCCTAGGGGTATTTGCAAGCCTGGCCAAGCAGTGCCAAAGACCGTGGGTGTATTATGTC
CCCTTTGTGTTTTTACAAGACGGCAGCGCCTATCCTTCGATGCTATCACCAAAATTGTGGCTGATGGGAGAGAAGACTGC
AGATTCTATCGATAAAGTGGCGGTGCTGCAGCCGCTAATAGCGCAGGCTCAGCAAAGCTATGTTAGCGATATTGCCACCA
TTGAGTTTTCTCGTAGTGCCATTATGAGCATGCTGGCCACCCGAGTCAGCTTTATGAATGAATGGTCGAGACTGGCCGAT
CAGCAGGGCGTAGATATCCTTGAGGTTGCCAATATTATGGGGTTAGATACCCGTATCGGCAGCAGCTATCTAAAAGCAGG
CTGGGGCTTTGGCGGTCAAACCTTGCCGGCTGAGATTAGCGCCCTACAGCAAACCTTACAAAATACTCAGGTTGAACATC
GCCTAATGCAGGCGGTCAATATCATTAATGATGACCAAAAAGAACTGATTTTCCGTAAATTCTGGCAGCATTTTGATGGT
GCCATTGAAAACAAACAGGTGAGTATATGGGGCGCAAGCTATAAAGCAGGCTCAGGGCGCACTTCCGCCTCTGCCATTCA
TCCGTTACTACGCCTATTGTGGTCATACAACATTACCACCCATATCTATGCGCTAGAGGCACAGTCTGAGCTGGCAAGTC
TATACCCTGATCAGCCGCTGTTACAGTTTATTGACTCTGCCACCGATAAGTTGGCCGATAGCGATGCGTTATTTGTGCTG
TCTTGGCCAAGCACCAAGCGTCTACCTATCAGTGCCATTAATGAGGTGGTGGTGCCAGTCTTTGATGCCCAAAATGCCTT
TGCAAAAACTCAAGTGGCCGCTTTAGTAGGTACGTATCAAGGAATTGGCCGCAGTAAATAA

Upstream 100 bases:

>100_bases
ACAGCTAAGCGCACAAAAGCTTACTGTTGGCCATCACTGCTGAGCCCAATGTGCCCCACTGACTCTATTACCATTAAAAA
ATATTAAGGATATGCGTATC

Downstream 100 bases:

>100_bases
CCACCCTAATTTCAAATCCATGTCACTAAAAAACCCCGCGGACTTACTGTAAGTCGCGGGGTCTTGGTTTACCTATCTAG
CGGCTGATTGAACGGGGTAA

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MATSTHSPAAPSKAVTDHCVIVGHSIDAITTATVMVSLGNQVCLYADQQALQHTLETYTFEHQQQALWQLYLNQNSIVVQ
DMPQLASQLFSNTKASFYWLFYGDLPSSWQALDGVQQAWVSELNDSQVPSQTPVIFSGISTLGVFASLAKQCQRPWVYYV
PFVFLQDGSAYPSMLSPKLWLMGEKTADSIDKVAVLQPLIAQAQQSYVSDIATIEFSRSAIMSMLATRVSFMNEWSRLAD
QQGVDILEVANIMGLDTRIGSSYLKAGWGFGGQTLPAEISALQQTLQNTQVEHRLMQAVNIINDDQKELIFRKFWQHFDG
AIENKQVSIWGASYKAGSGRTSASAIHPLLRLLWSYNITTHIYALEAQSELASLYPDQPLLQFIDSATDKLADSDALFVL
SWPSTKRLPISAINEVVVPVFDAQNAFAKTQVAALVGTYQGIGRSK

Sequences:

>Translated_446_residues
MATSTHSPAAPSKAVTDHCVIVGHSIDAITTATVMVSLGNQVCLYADQQALQHTLETYTFEHQQQALWQLYLNQNSIVVQ
DMPQLASQLFSNTKASFYWLFYGDLPSSWQALDGVQQAWVSELNDSQVPSQTPVIFSGISTLGVFASLAKQCQRPWVYYV
PFVFLQDGSAYPSMLSPKLWLMGEKTADSIDKVAVLQPLIAQAQQSYVSDIATIEFSRSAIMSMLATRVSFMNEWSRLAD
QQGVDILEVANIMGLDTRIGSSYLKAGWGFGGQTLPAEISALQQTLQNTQVEHRLMQAVNIINDDQKELIFRKFWQHFDG
AIENKQVSIWGASYKAGSGRTSASAIHPLLRLLWSYNITTHIYALEAQSELASLYPDQPLLQFIDSATDKLADSDALFVL
SWPSTKRLPISAINEVVVPVFDAQNAFAKTQVAALVGTYQGIGRSK
>Mature_445_residues
ATSTHSPAAPSKAVTDHCVIVGHSIDAITTATVMVSLGNQVCLYADQQALQHTLETYTFEHQQQALWQLYLNQNSIVVQD
MPQLASQLFSNTKASFYWLFYGDLPSSWQALDGVQQAWVSELNDSQVPSQTPVIFSGISTLGVFASLAKQCQRPWVYYVP
FVFLQDGSAYPSMLSPKLWLMGEKTADSIDKVAVLQPLIAQAQQSYVSDIATIEFSRSAIMSMLATRVSFMNEWSRLADQ
QGVDILEVANIMGLDTRIGSSYLKAGWGFGGQTLPAEISALQQTLQNTQVEHRLMQAVNIINDDQKELIFRKFWQHFDGA
IENKQVSIWGASYKAGSGRTSASAIHPLLRLLWSYNITTHIYALEAQSELASLYPDQPLLQFIDSATDKLADSDALFVLS
WPSTKRLPISAINEVVVPVFDAQNAFAKTQVAALVGTYQGIGRSK

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296040443, Length=206, Percent_Identity=26.2135922330097, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4507813, Length=206, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI296040438, Length=206, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788340, Length=226, Percent_Identity=26.5486725663717, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560350, Length=281, Percent_Identity=27.0462633451957, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17136908, Length=227, Percent_Identity=26.431718061674, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49291; Mature: 49160

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSTHSPAAPSKAVTDHCVIVGHSIDAITTATVMVSLGNQVCLYADQQALQHTLETYTF
CCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
EHQQQALWQLYLNQNSIVVQDMPQLASQLFSNTKASFYWLFYGDLPSSWQALDGVQQAWV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
SELNDSQVPSQTPVIFSGISTLGVFASLAKQCQRPWVYYVPFVFLQDGSAYPSMLSPKLW
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHCCCCEE
LMGEKTADSIDKVAVLQPLIAQAQQSYVSDIATIEFSRSAIMSMLATRVSFMNEWSRLAD
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQGVDILEVANIMGLDTRIGSSYLKAGWGFGGQTLPAEISALQQTLQNTQVEHRLMQAVN
HCCCHHHHHHHHHCCCHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IINDDQKELIFRKFWQHFDGAIENKQVSIWGASYKAGSGRTSASAIHPLLRLLWSYNITT
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEE
HIYALEAQSELASLYPDQPLLQFIDSATDKLADSDALFVLSWPSTKRLPISAINEVVVPV
EEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHEEE
FDAQNAFAKTQVAALVGTYQGIGRSK
ECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ATSTHSPAAPSKAVTDHCVIVGHSIDAITTATVMVSLGNQVCLYADQQALQHTLETYTF
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
EHQQQALWQLYLNQNSIVVQDMPQLASQLFSNTKASFYWLFYGDLPSSWQALDGVQQAWV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
SELNDSQVPSQTPVIFSGISTLGVFASLAKQCQRPWVYYVPFVFLQDGSAYPSMLSPKLW
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHCCCCEE
LMGEKTADSIDKVAVLQPLIAQAQQSYVSDIATIEFSRSAIMSMLATRVSFMNEWSRLAD
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQGVDILEVANIMGLDTRIGSSYLKAGWGFGGQTLPAEISALQQTLQNTQVEHRLMQAVN
HCCCHHHHHHHHHCCCHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IINDDQKELIFRKFWQHFDGAIENKQVSIWGASYKAGSGRTSASAIHPLLRLLWSYNITT
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEE
HIYALEAQSELASLYPDQPLLQFIDSATDKLADSDALFVLSWPSTKRLPISAINEVVVPV
EEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHEEE
FDAQNAFAKTQVAALVGTYQGIGRSK
ECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]