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The map label for this gene is pgi [H]

Identifier: 148652084

GI number: 148652084

Start: 322978

End: 324669

Strand: Direct

Name: pgi [H]

Synonym: PsycPRwf_0272

Alternate gene names: 148652084

Gene position: 322978-324669 (Clockwise)

Preceding gene: 148652083

Following gene: 148652085

Centisome position: 10.84

GC content: 49.65

Gene sequence:

>1692_bases
ATGGATAAAACCTTGCCCAATCAGCTGCCCCAATGGCAAAGGCTTCAGCAATTAGCGCAGCAGCCTTGGTCAATCACTGA
GTTATTTGCCAAAGATACCCATAGAAGCACCAACTTTAGCCTCAGTGCTCAAGGCATGTTTTTTGATTACTCCAAGCAGT
GCTTAGATGAATCGGTGAAAGCAGAGCTGTTTGAGTTGGCCAAAGCATGCCGATTGCCACAAAAGCTGGCTGCCTTGTAC
CAAGGCGATAAAGTCAATACCAGTGAAAAACGTGCAGCCCTGCACACCGCATTGCGTCTGCCTAAGTCGGCTCGTCTAAC
CGTAGATGGGGTAGATGTGGTGGCTGAGGTGCATGACAGCTTGGCCAAAGCAGAAGACTTGGTTGATCGCATTCGTGGCG
GTCTGTGGCGTGGCTATTCGGGCAAAGCCATCACTGATGTGGTCAATATTGGGGTAGGCGGCTCAGATTTGGGTCCGGTG
ATGGCCAATACCGCGCTCGATGAATGGGCAGACAGTAATATTCGAGTGCACTTTGTGTCTAACATGGATGGCACGCAATT
GGGCAGCCTGCTCGATAAGCTAAATCCAGAGACCACTCTGTTTATCATCTCATCTAAGTCTTTTGGTACCGTCGATACCT
TATCGAATGCACAAACGGCCCGAGCTTGGCTATTGACCACTGGTGCCAGTCCAGCTACTTTGTTGCGCCGTCATTTTATT
GGGATATCAGCCAATACGGAGCGAGTAAGTGCGTGGGGGATTGCCAAAGAGCATCAATTAAAGCTTTGGGACTGGGTAGG
TGGCCGCTTCTCTATGTGGTCAGCCATTGGTCTGGCTGTGGCCATCCGCATTGGGATGCCGCGATTTTATGAAATGCTGG
CGGGTGCTCACGCTATGGATGAGCACTTCAAGCACGCGGACTTTGAGCATAATTTACCCGTCTTGCTGGGACTTATCGGC
ATATGGAACAGCAGCTTTTTGGGGATTAATGCCCATACCGTATTGCCGTATGATGGCCGTTTAAAATATTTTCCAAGTTA
CCTAACCCAGCTTGAGATGGAAAGTAACGGTAAGTCGGTCACGCATGGCGGCCAGCCTGTGCCTTACGCCACCTGTCCTA
TCTTATGGGGTGAGATTGGCTCGAACGCTCAGCATGCTTTTTATCAGCTATTGCACCAAGGTACTCAAAAGGTGTCTTGT
GACTTTATTGCCTGTGTTAATTACTATCAAAGTCGTGAAGCTGACGAGCTCAAAAAGCAGCATGAGTTATCTTTGGCCAA
CTGCTTGGCACAAAGCCGAGTACTGGCCTTTGGTAACGATGCTTTAGCCGCTAAGCCTGATCAGGTGGCCACTGAGCTTG
ATAAATTTAAGCGTTACCGTGGTAATCAGCCCTCGACGACGTTGCTACTCGATGAGTTGACGCCAGCCAGCTTTGGCGCC
TTAATCGCGCTGTATGAGCACAAAGTATTTGTCATGGCCAGTATTTGGGACATCAACCCCTTTGATCAGTGGGGAGTGGA
GATGGGCAAACAGGTGGCCAATGAGGTGTTTGCTCATATTCGATTGGATACATCTGTGGCCTCTGACGCAGCAGCAGATC
ACGCTCATAAACAGGCTCAGCTTGCTGCAGAAGCCTTTGATGGCTCGACTCAAGCATTGCTGCAGCACATTAATCAGCAG
TTAGACAGCTAA

Upstream 100 bases:

>100_bases
GATAAATAGCACTGTGCGAACATGACTTTAGCTTTCTATGAGGTTAGGGATACAAACATTAAACGCTTTTTGTAACACTT
AATTTTTGAGTACTCTGTTT

Downstream 100 bases:

>100_bases
GCGCACAAAAGCTTACTGTTGGCCATCACTGCTGAGCCCAATGTGCCCCACTGACTCTATTACCATTAAAAAATATTAAG
GATATGCGTATCATGGCAAC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MDKTLPNQLPQWQRLQQLAQQPWSITELFAKDTHRSTNFSLSAQGMFFDYSKQCLDESVKAELFELAKACRLPQKLAALY
QGDKVNTSEKRAALHTALRLPKSARLTVDGVDVVAEVHDSLAKAEDLVDRIRGGLWRGYSGKAITDVVNIGVGGSDLGPV
MANTALDEWADSNIRVHFVSNMDGTQLGSLLDKLNPETTLFIISSKSFGTVDTLSNAQTARAWLLTTGASPATLLRRHFI
GISANTERVSAWGIAKEHQLKLWDWVGGRFSMWSAIGLAVAIRIGMPRFYEMLAGAHAMDEHFKHADFEHNLPVLLGLIG
IWNSSFLGINAHTVLPYDGRLKYFPSYLTQLEMESNGKSVTHGGQPVPYATCPILWGEIGSNAQHAFYQLLHQGTQKVSC
DFIACVNYYQSREADELKKQHELSLANCLAQSRVLAFGNDALAAKPDQVATELDKFKRYRGNQPSTTLLLDELTPASFGA
LIALYEHKVFVMASIWDINPFDQWGVEMGKQVANEVFAHIRLDTSVASDAAADHAHKQAQLAAEAFDGSTQALLQHINQQ
LDS

Sequences:

>Translated_563_residues
MDKTLPNQLPQWQRLQQLAQQPWSITELFAKDTHRSTNFSLSAQGMFFDYSKQCLDESVKAELFELAKACRLPQKLAALY
QGDKVNTSEKRAALHTALRLPKSARLTVDGVDVVAEVHDSLAKAEDLVDRIRGGLWRGYSGKAITDVVNIGVGGSDLGPV
MANTALDEWADSNIRVHFVSNMDGTQLGSLLDKLNPETTLFIISSKSFGTVDTLSNAQTARAWLLTTGASPATLLRRHFI
GISANTERVSAWGIAKEHQLKLWDWVGGRFSMWSAIGLAVAIRIGMPRFYEMLAGAHAMDEHFKHADFEHNLPVLLGLIG
IWNSSFLGINAHTVLPYDGRLKYFPSYLTQLEMESNGKSVTHGGQPVPYATCPILWGEIGSNAQHAFYQLLHQGTQKVSC
DFIACVNYYQSREADELKKQHELSLANCLAQSRVLAFGNDALAAKPDQVATELDKFKRYRGNQPSTTLLLDELTPASFGA
LIALYEHKVFVMASIWDINPFDQWGVEMGKQVANEVFAHIRLDTSVASDAAADHAHKQAQLAAEAFDGSTQALLQHINQQ
LDS
>Mature_563_residues
MDKTLPNQLPQWQRLQQLAQQPWSITELFAKDTHRSTNFSLSAQGMFFDYSKQCLDESVKAELFELAKACRLPQKLAALY
QGDKVNTSEKRAALHTALRLPKSARLTVDGVDVVAEVHDSLAKAEDLVDRIRGGLWRGYSGKAITDVVNIGVGGSDLGPV
MANTALDEWADSNIRVHFVSNMDGTQLGSLLDKLNPETTLFIISSKSFGTVDTLSNAQTARAWLLTTGASPATLLRRHFI
GISANTERVSAWGIAKEHQLKLWDWVGGRFSMWSAIGLAVAIRIGMPRFYEMLAGAHAMDEHFKHADFEHNLPVLLGLIG
IWNSSFLGINAHTVLPYDGRLKYFPSYLTQLEMESNGKSVTHGGQPVPYATCPILWGEIGSNAQHAFYQLLHQGTQKVSC
DFIACVNYYQSREADELKKQHELSLANCLAQSRVLAFGNDALAAKPDQVATELDKFKRYRGNQPSTTLLLDELTPASFGA
LIALYEHKVFVMASIWDINPFDQWGVEMGKQVANEVFAHIRLDTSVASDAAADHAHKQAQLAAEAFDGSTQALLQHINQQ
LDS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=569, Percent_Identity=42.1792618629174, Blast_Score=461, Evalue=1e-129,
Organism=Homo sapiens, GI296080693, Length=569, Percent_Identity=38.6643233743409, Blast_Score=398, Evalue=1e-111,
Organism=Escherichia coli, GI1790457, Length=539, Percent_Identity=45.2690166975881, Blast_Score=474, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71996703, Length=537, Percent_Identity=42.0856610800745, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71996708, Length=537, Percent_Identity=42.0856610800745, Blast_Score=428, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6319673, Length=536, Percent_Identity=41.4179104477612, Blast_Score=440, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24651916, Length=534, Percent_Identity=44.0074906367041, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24651914, Length=534, Percent_Identity=44.0074906367041, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17737445, Length=534, Percent_Identity=44.0074906367041, Blast_Score=456, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 62210; Mature: 62210

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTLPNQLPQWQRLQQLAQQPWSITELFAKDTHRSTNFSLSAQGMFFDYSKQCLDESVK
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCEEEHHHHHHHHHHHH
AELFELAKACRLPQKLAALYQGDKVNTSEKRAALHTALRLPKSARLTVDGVDVVAEVHDS
HHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
LAKAEDLVDRIRGGLWRGYSGKAITDVVNIGVGGSDLGPVMANTALDEWADSNIRVHFVS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
NMDGTQLGSLLDKLNPETTLFIISSKSFGTVDTLSNAQTARAWLLTTGASPATLLRRHFI
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCHHHEEEEEECCCCHHHHHHHHHC
GISANTERVSAWGIAKEHQLKLWDWVGGRFSMWSAIGLAVAIRIGMPRFYEMLAGAHAMD
CCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
EHFKHADFEHNLPVLLGLIGIWNSSFLGINAHTVLPYDGRLKYFPSYLTQLEMESNGKSV
HHHHCCCCCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEE
THGGQPVPYATCPILWGEIGSNAQHAFYQLLHQGTQKVSCDFIACVNYYQSREADELKKQ
CCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCHHHHHHH
HELSLANCLAQSRVLAFGNDALAAKPDQVATELDKFKRYRGNQPSTTLLLDELTPASFGA
HHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
LIALYEHKVFVMASIWDINPFDQWGVEMGKQVANEVFAHIRLDTSVASDAAADHAHKQAQ
HHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LAAEAFDGSTQALLQHINQQLDS
HHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKTLPNQLPQWQRLQQLAQQPWSITELFAKDTHRSTNFSLSAQGMFFDYSKQCLDESVK
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCEEEHHHHHHHHHHHH
AELFELAKACRLPQKLAALYQGDKVNTSEKRAALHTALRLPKSARLTVDGVDVVAEVHDS
HHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
LAKAEDLVDRIRGGLWRGYSGKAITDVVNIGVGGSDLGPVMANTALDEWADSNIRVHFVS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
NMDGTQLGSLLDKLNPETTLFIISSKSFGTVDTLSNAQTARAWLLTTGASPATLLRRHFI
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCHHHEEEEEECCCCHHHHHHHHHC
GISANTERVSAWGIAKEHQLKLWDWVGGRFSMWSAIGLAVAIRIGMPRFYEMLAGAHAMD
CCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
EHFKHADFEHNLPVLLGLIGIWNSSFLGINAHTVLPYDGRLKYFPSYLTQLEMESNGKSV
HHHHCCCCCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEE
THGGQPVPYATCPILWGEIGSNAQHAFYQLLHQGTQKVSCDFIACVNYYQSREADELKKQ
CCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCHHHHHHH
HELSLANCLAQSRVLAFGNDALAAKPDQVATELDKFKRYRGNQPSTTLLLDELTPASFGA
HHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
LIALYEHKVFVMASIWDINPFDQWGVEMGKQVANEVFAHIRLDTSVASDAAADHAHKQAQ
HHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LAAEAFDGSTQALLQHINQQLDS
HHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA