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The map label for this gene is moaA [H]

Identifier: 148652033

GI number: 148652033

Start: 257966

End: 259279

Strand: Direct

Name: moaA [H]

Synonym: PsycPRwf_0217

Alternate gene names: 148652033

Gene position: 257966-259279 (Clockwise)

Preceding gene: 148652032

Following gene: 148652034

Centisome position: 8.66

GC content: 48.02

Gene sequence:

>1314_bases
ATGACTACGGTACCCCATATGACCCTTCTTAATTCCAACCTAAGGAAAGCTAGGCTATACACACCTTCCCCCAATTCAGT
TATGTTTGATGGTCATGTTCCGCTGTCATCTGCTCATGCGCTCTTGCATCCTACTGTTAACTCTATCAATGCGTTTACCC
ACTCTGCCATACCCTCTGTTGCAAGCGCCTCTTTTTCCTGGCCAAAAGCGACAAAGCCGGCTGACTTTATGTCGCCCTTT
ACCCAGCTTGCGCGCAGTACCTTGACCACACTAAGATCTACCAAAGGCTCAGCGGCTGCCTCTGTGAGCAGTCATGTGCC
CCAAACCAATGACACTGATGCTCTATTGACCGATGGCTTCTCAAGGCGCTTGACCTATTTGCGCCTATCGATTACTGATT
TTTGTAATTTTCGCTGTGGCTATTGTCTGCCCAATGGCTATCAAGGCAAGCGTCCGGACAATGAGCTGACTTTGCAAGAG
ATTGAGGTATTGATTAAGGCCTTTGCTCAAGTGGGCACAAAAAAGGTGCGTTTAACCGGTGGCGAGCCATCTATCCGAAA
AGATGTCACTCAAATTATTGAGCAAGTCAAAGCCACGCCCGGCATCCAAACTGTGGCGATGACCAGCAATGGCTATAAAC
TGGGCAAGCACGTCGCTAATTGGCAACAAGCCGGCCTTGATCAATTAAACATCAGTGTCGATAGCTTTGATCCGGCCACG
TTTAAGCAAATGACTGGTTTTGATATGTTGCCGCAGCTGCTACAGGACATGGATACGCTGCTAGAGACGACTGATATCAA
GCTCAAGCTCAATGGCATCTTGATGGAAGAGACTGCTTACGACAGTCTGCTTGCAGCCTTACACTATGTCAAAACGCGTC
CGGTCACCTACCGCTTTATCGAGTTTATGCAGACCACTGACAACAGTGATCTATTTTTTGCGCAGCATGCACAGTCAGCG
CTGATTACCGATTATTTGCTAAGTCATGGCTGGCAAGCGCAGGATAGAGGCCAAAATGATGGCCCAGCCATGGAGTACAC
TCACCCCGATTATGTGGGCCGTATTGGTATGATTGCCCCCTATGCGGCGCACTTTTGTGACAGCTGTAATCGACTGCGGG
TCAGCAGCCTAGGTAAGGTGCATTTGTGCTTATTTGATCAAGGCAACTACGATATCCGTCAATATTTACAGCAGCAAGAT
GTGGCGGGTCTGGTACAAAAACTCCATGAATTTATGCCGATAAAACCTGAGCACCATCACTTGGCAGAATCCAACAGTGG
CATTATGCACAACTTATCGATGATTGGTGGTTAA

Upstream 100 bases:

>100_bases
AAGTATCTATTAGGCCGCAACCTGTTATAATGACGTTATCGCAACTTTTTTAAGTTTTTATTCACAACCTGAGGCAACGC
TTAGAGCACATTCACTACTA

Downstream 100 bases:

>100_bases
CAGGATTGGCGGCTAAGCCAAAAGGTACGTTTCAAAGCCATCTGTTTAAATCTTAATTGTTTTCCCTGTTATTTAAGGCG
CTTTTATGTCAAAAGAAAAA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTTVPHMTLLNSNLRKARLYTPSPNSVMFDGHVPLSSAHALLHPTVNSINAFTHSAIPSVASASFSWPKATKPADFMSPF
TQLARSTLTTLRSTKGSAAASVSSHVPQTNDTDALLTDGFSRRLTYLRLSITDFCNFRCGYCLPNGYQGKRPDNELTLQE
IEVLIKAFAQVGTKKVRLTGGEPSIRKDVTQIIEQVKATPGIQTVAMTSNGYKLGKHVANWQQAGLDQLNISVDSFDPAT
FKQMTGFDMLPQLLQDMDTLLETTDIKLKLNGILMEETAYDSLLAALHYVKTRPVTYRFIEFMQTTDNSDLFFAQHAQSA
LITDYLLSHGWQAQDRGQNDGPAMEYTHPDYVGRIGMIAPYAAHFCDSCNRLRVSSLGKVHLCLFDQGNYDIRQYLQQQD
VAGLVQKLHEFMPIKPEHHHLAESNSGIMHNLSMIGG

Sequences:

>Translated_437_residues
MTTVPHMTLLNSNLRKARLYTPSPNSVMFDGHVPLSSAHALLHPTVNSINAFTHSAIPSVASASFSWPKATKPADFMSPF
TQLARSTLTTLRSTKGSAAASVSSHVPQTNDTDALLTDGFSRRLTYLRLSITDFCNFRCGYCLPNGYQGKRPDNELTLQE
IEVLIKAFAQVGTKKVRLTGGEPSIRKDVTQIIEQVKATPGIQTVAMTSNGYKLGKHVANWQQAGLDQLNISVDSFDPAT
FKQMTGFDMLPQLLQDMDTLLETTDIKLKLNGILMEETAYDSLLAALHYVKTRPVTYRFIEFMQTTDNSDLFFAQHAQSA
LITDYLLSHGWQAQDRGQNDGPAMEYTHPDYVGRIGMIAPYAAHFCDSCNRLRVSSLGKVHLCLFDQGNYDIRQYLQQQD
VAGLVQKLHEFMPIKPEHHHLAESNSGIMHNLSMIGG
>Mature_436_residues
TTVPHMTLLNSNLRKARLYTPSPNSVMFDGHVPLSSAHALLHPTVNSINAFTHSAIPSVASASFSWPKATKPADFMSPFT
QLARSTLTTLRSTKGSAAASVSSHVPQTNDTDALLTDGFSRRLTYLRLSITDFCNFRCGYCLPNGYQGKRPDNELTLQEI
EVLIKAFAQVGTKKVRLTGGEPSIRKDVTQIIEQVKATPGIQTVAMTSNGYKLGKHVANWQQAGLDQLNISVDSFDPATF
KQMTGFDMLPQLLQDMDTLLETTDIKLKLNGILMEETAYDSLLAALHYVKTRPVTYRFIEFMQTTDNSDLFFAQHAQSAL
ITDYLLSHGWQAQDRGQNDGPAMEYTHPDYVGRIGMIAPYAAHFCDSCNRLRVSSLGKVHLCLFDQGNYDIRQYLQQQDV
AGLVQKLHEFMPIKPEHHHLAESNSGIMHNLSMIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=287, Percent_Identity=32.7526132404181, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI22027536, Length=287, Percent_Identity=32.7526132404181, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1786999, Length=328, Percent_Identity=46.3414634146341, Blast_Score=310, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI32566331, Length=290, Percent_Identity=35.8620689655172, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI32566329, Length=348, Percent_Identity=32.4712643678161, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17561210, Length=290, Percent_Identity=35.8620689655172, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574490, Length=351, Percent_Identity=32.7635327635328, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI28574488, Length=321, Percent_Identity=33.6448598130841, Blast_Score=190, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 48530; Mature: 48399

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVPHMTLLNSNLRKARLYTPSPNSVMFDGHVPLSSAHALLHPTVNSINAFTHSAIPSV
CCCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCHHCCCCHHHHHHHHHHHCCHH
ASASFSWPKATKPADFMSPFTQLARSTLTTLRSTKGSAAASVSSHVPQTNDTDALLTDGF
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHCCH
SRRLTYLRLSITDFCNFRCGYCLPNGYQGKRPDNELTLQEIEVLIKAFAQVGTKKVRLTG
HHHHEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
GEPSIRKDVTQIIEQVKATPGIQTVAMTSNGYKLGKHVANWQQAGLDQLNISVDSFDPAT
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCHH
FKQMTGFDMLPQLLQDMDTLLETTDIKLKLNGILMEETAYDSLLAALHYVKTRPVTYRFI
HHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCEEECHHHHHHHHHHHHHHHCCCHHHHHH
EFMQTTDNSDLFFAQHAQSALITDYLLSHGWQAQDRGQNDGPAMEYTHPDYVGRIGMIAP
HHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
YAAHFCDSCNRLRVSSLGKVHLCLFDQGNYDIRQYLQQQDVAGLVQKLHEFMPIKPEHHH
HHHHHHCCCCCEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LAESNSGIMHNLSMIGG
HHCCCCCCEEHHHHHCC
>Mature Secondary Structure 
TTVPHMTLLNSNLRKARLYTPSPNSVMFDGHVPLSSAHALLHPTVNSINAFTHSAIPSV
CCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCHHCCCCHHHHHHHHHHHCCHH
ASASFSWPKATKPADFMSPFTQLARSTLTTLRSTKGSAAASVSSHVPQTNDTDALLTDGF
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHCCH
SRRLTYLRLSITDFCNFRCGYCLPNGYQGKRPDNELTLQEIEVLIKAFAQVGTKKVRLTG
HHHHEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
GEPSIRKDVTQIIEQVKATPGIQTVAMTSNGYKLGKHVANWQQAGLDQLNISVDSFDPAT
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCHH
FKQMTGFDMLPQLLQDMDTLLETTDIKLKLNGILMEETAYDSLLAALHYVKTRPVTYRFI
HHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCEEECHHHHHHHHHHHHHHHCCCHHHHHH
EFMQTTDNSDLFFAQHAQSALITDYLLSHGWQAQDRGQNDGPAMEYTHPDYVGRIGMIAP
HHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
YAAHFCDSCNRLRVSSLGKVHLCLFDQGNYDIRQYLQQQDVAGLVQKLHEFMPIKPEHHH
HHHHHHCCCCCEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LAESNSGIMHNLSMIGG
HHCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA