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The map label for this gene is rstB [H]

Identifier: 148652014

GI number: 148652014

Start: 234457

End: 236148

Strand: Direct

Name: rstB [H]

Synonym: PsycPRwf_0198

Alternate gene names: 148652014

Gene position: 234457-236148 (Clockwise)

Preceding gene: 148652013

Following gene: 148652016

Centisome position: 7.87

GC content: 46.51

Gene sequence:

>1692_bases
ATGCCAATATTCTCATCCTTAAAACATAGTATTTTTCTGCGCATCTATGCCGGCTTATTATTGGTTTGTCTTTTTGTTGC
CTTATTTGCCCAGCTGTTGGTGGACACTATCAATAACGAGCGCATTCAAACTTATAGAGAAAATGTGGCCACAGGCGCTT
TATATTTGGTCAGCTCGGGTCTAAAGCAGCAAGCTTCTGAGACCCAGCGTGAATATTGGCTTAATGACATCAGTCAATTA
TTTGGTAATAATTTTAGTATTCAGCCAGAGTCAAGTATCGACTTTAAGGCCAGTGAGCTCAAGCGTTTAGAGCAACAAAA
AACAGTGGTACGTTATGTCGCTCAGCCGGCCTATGCCGACATTTTTCATCCTATCGAGGGTGAAGATAATGTCATTACCG
TGCGTATTAGCAAAGTCACTGAGCAACAAGTGCGTGCCATGGCAGTACTGCTTTTAAATGATTTGTCCTACTTTCCTGAC
CTTGAAAGCAAGCGTCAGCGTCTTAGTGAAATTTCAGAAAAATTCGCGTTTCCACTTAGCATTGAAAATGTTGATAAGCT
TGAACTAGATGATGATCAACTGCGCCGCCTAGACCGTGATGAAGTGGTCATACTGTTTCGTGACAGTACCCGCTCTGATG
ATTCCTCTATTAAGGTTATAGCGCCCTCTGAGCTTGAGAATATGGCGTTGGTTATTGGGCCGGTTAGTCTGTTTAAGTGG
TTCCCCTTTAATCTGATTATCAGTGTGGTGCTTATCAGCATGTTCCTTATTAGTTTGGGAGTTTATGCACTGATTTTCCC
ACTTGAGCGCAAATTGCAACTGATTCAGTCCGGTGTTAATGAGGTCGGCGATGGTAATTTAGATACCCGCGTGCAGGTGG
TGGGTCAAGATGAGATTGCCCGATTGGCCGCCACCTTCAACGCCATGACTGAGCACATCAAGCGCCTTATTGAGTCACAG
CGGGAGCTAACCCGAGCGGTGTCACATGAGCTGCGCACCCCTGTGGCACGTATTCGCTTTGCGGTAGATATGTTGGCAGA
TACTGAAGATCAAGAATCTCGAGAGATGCAGCGCGACTATATCGATGAAGATATTGAGTCGTTAAATGGTCTTATTGATG
AGATTTTAACTTACGCTAAGTTAGAAGAAGGCTCGCCTAAGCTAGACCTTGAGCCGGTGAGCCTAAAAGAGCTGGTCGAT
CAGATTGTGCGTGAGACCAATGCGTTAGGTAAGCCTATTGAGATAGTGGGTATAGCACCGACAGCCAAGGTGACTGCGGT
GGCAGACAGACGCTACCTACACCGTGTGGTGCAGAACTTGGCGGGTAATGCCTTGCGATATGCTGAGTCGAAGATTGTTA
TTAGTGCCGGCGTACGTAAAGGCGAGGCTTTTGTGTCGGTAGAAGATGATGGCCACGGTATTCCAGAAGAAGATCGCGAT
AAGGTATTCGTGCCTTTTGCGCGCTTAGATGACAGTCGCACGCGCGCTTCAGGGGGCTATGGCCTCGGGCTATCTATCGT
GTCACGTATTGCGTTTTGGTTTAATGGCACCATGTCTGTGGATGAAAGTCCGAAATTGGGCGGCGCTCGCTTTACCATGA
ATTGGCCGATTAAGCCGTTAACCCAGACCATTTCAGCCGATCAATTAACGCAAGAAAAAGGCGCTCGTAAACTGATAGAC
AGCGACAGCTAA

Upstream 100 bases:

>100_bases
ACGGGTAGCGTTAGTAGACACTGGCAGCAGCTTGATCATCGGTAGGTTAAAAATCCAAATTAGGGTAAACTAGGATAAAA
TTAATTTTATTAGATGTCAT

Downstream 100 bases:

>100_bases
TCCATTAGCTGTCCTATTGTCTGGCCTTACTCATACTGGTCTTGCTCATACGGACCCTATTCATGATAGGCTTCTACGTC
ATCCTCATCGTTAGGCTCCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MPIFSSLKHSIFLRIYAGLLLVCLFVALFAQLLVDTINNERIQTYRENVATGALYLVSSGLKQQASETQREYWLNDISQL
FGNNFSIQPESSIDFKASELKRLEQQKTVVRYVAQPAYADIFHPIEGEDNVITVRISKVTEQQVRAMAVLLLNDLSYFPD
LESKRQRLSEISEKFAFPLSIENVDKLELDDDQLRRLDRDEVVILFRDSTRSDDSSIKVIAPSELENMALVIGPVSLFKW
FPFNLIISVVLISMFLISLGVYALIFPLERKLQLIQSGVNEVGDGNLDTRVQVVGQDEIARLAATFNAMTEHIKRLIESQ
RELTRAVSHELRTPVARIRFAVDMLADTEDQESREMQRDYIDEDIESLNGLIDEILTYAKLEEGSPKLDLEPVSLKELVD
QIVRETNALGKPIEIVGIAPTAKVTAVADRRYLHRVVQNLAGNALRYAESKIVISAGVRKGEAFVSVEDDGHGIPEEDRD
KVFVPFARLDDSRTRASGGYGLGLSIVSRIAFWFNGTMSVDESPKLGGARFTMNWPIKPLTQTISADQLTQEKGARKLID
SDS

Sequences:

>Translated_563_residues
MPIFSSLKHSIFLRIYAGLLLVCLFVALFAQLLVDTINNERIQTYRENVATGALYLVSSGLKQQASETQREYWLNDISQL
FGNNFSIQPESSIDFKASELKRLEQQKTVVRYVAQPAYADIFHPIEGEDNVITVRISKVTEQQVRAMAVLLLNDLSYFPD
LESKRQRLSEISEKFAFPLSIENVDKLELDDDQLRRLDRDEVVILFRDSTRSDDSSIKVIAPSELENMALVIGPVSLFKW
FPFNLIISVVLISMFLISLGVYALIFPLERKLQLIQSGVNEVGDGNLDTRVQVVGQDEIARLAATFNAMTEHIKRLIESQ
RELTRAVSHELRTPVARIRFAVDMLADTEDQESREMQRDYIDEDIESLNGLIDEILTYAKLEEGSPKLDLEPVSLKELVD
QIVRETNALGKPIEIVGIAPTAKVTAVADRRYLHRVVQNLAGNALRYAESKIVISAGVRKGEAFVSVEDDGHGIPEEDRD
KVFVPFARLDDSRTRASGGYGLGLSIVSRIAFWFNGTMSVDESPKLGGARFTMNWPIKPLTQTISADQLTQEKGARKLID
SDS
>Mature_562_residues
PIFSSLKHSIFLRIYAGLLLVCLFVALFAQLLVDTINNERIQTYRENVATGALYLVSSGLKQQASETQREYWLNDISQLF
GNNFSIQPESSIDFKASELKRLEQQKTVVRYVAQPAYADIFHPIEGEDNVITVRISKVTEQQVRAMAVLLLNDLSYFPDL
ESKRQRLSEISEKFAFPLSIENVDKLELDDDQLRRLDRDEVVILFRDSTRSDDSSIKVIAPSELENMALVIGPVSLFKWF
PFNLIISVVLISMFLISLGVYALIFPLERKLQLIQSGVNEVGDGNLDTRVQVVGQDEIARLAATFNAMTEHIKRLIESQR
ELTRAVSHELRTPVARIRFAVDMLADTEDQESREMQRDYIDEDIESLNGLIDEILTYAKLEEGSPKLDLEPVSLKELVDQ
IVRETNALGKPIEIVGIAPTAKVTAVADRRYLHRVVQNLAGNALRYAESKIVISAGVRKGEAFVSVEDDGHGIPEEDRDK
VFVPFARLDDSRTRASGGYGLGLSIVSRIAFWFNGTMSVDESPKLGGARFTMNWPIKPLTQTISADQLTQEKGARKLIDS
DS

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=375, Percent_Identity=33.6, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=30.9701492537313, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=29.4736842105263, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788393, Length=281, Percent_Identity=29.1814946619217, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=288, Percent_Identity=28.8194444444444, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=27.6450511945392, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=28.8702928870293, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=26.4925373134328, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=300, Percent_Identity=26, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790551, Length=295, Percent_Identity=27.1186440677966, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786600, Length=251, Percent_Identity=26.2948207171315, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=25.0936329588015, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=216, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=28.9256198347107, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=25.5737704918033, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=27.5862068965517, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63330; Mature: 63199

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIFSSLKHSIFLRIYAGLLLVCLFVALFAQLLVDTINNERIQTYRENVATGALYLVSSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LKQQASETQREYWLNDISQLFGNNFSIQPESSIDFKASELKRLEQQKTVVRYVAQPAYAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
IFHPIEGEDNVITVRISKVTEQQVRAMAVLLLNDLSYFPDLESKRQRLSEISEKFAFPLS
HCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
IENVDKLELDDDQLRRLDRDEVVILFRDSTRSDDSSIKVIAPSELENMALVIGPVSLFKW
CCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEHHHHHHH
FPFNLIISVVLISMFLISLGVYALIFPLERKLQLIQSGVNEVGDGNLDTRVQVVGQDEIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHH
RLAATFNAMTEHIKRLIESQRELTRAVSHELRTPVARIRFAVDMLADTEDQESREMQRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
IDEDIESLNGLIDEILTYAKLEEGSPKLDLEPVSLKELVDQIVRETNALGKPIEIVGIAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TAKVTAVADRRYLHRVVQNLAGNALRYAESKIVISAGVRKGEAFVSVEDDGHGIPEEDRD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEECCCCCCCEEEEECCCCCCCCCCCCC
KVFVPFARLDDSRTRASGGYGLGLSIVSRIAFWFNGTMSVDESPKLGGARFTMNWPIKPL
CEEEEHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHH
TQTISADQLTQEKGARKLIDSDS
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PIFSSLKHSIFLRIYAGLLLVCLFVALFAQLLVDTINNERIQTYRENVATGALYLVSSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LKQQASETQREYWLNDISQLFGNNFSIQPESSIDFKASELKRLEQQKTVVRYVAQPAYAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
IFHPIEGEDNVITVRISKVTEQQVRAMAVLLLNDLSYFPDLESKRQRLSEISEKFAFPLS
HCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
IENVDKLELDDDQLRRLDRDEVVILFRDSTRSDDSSIKVIAPSELENMALVIGPVSLFKW
CCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEHHHHHHH
FPFNLIISVVLISMFLISLGVYALIFPLERKLQLIQSGVNEVGDGNLDTRVQVVGQDEIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHH
RLAATFNAMTEHIKRLIESQRELTRAVSHELRTPVARIRFAVDMLADTEDQESREMQRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
IDEDIESLNGLIDEILTYAKLEEGSPKLDLEPVSLKELVDQIVRETNALGKPIEIVGIAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TAKVTAVADRRYLHRVVQNLAGNALRYAESKIVISAGVRKGEAFVSVEDDGHGIPEEDRD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEECCCCCCCEEEEECCCCCCCCCCCCC
KVFVPFARLDDSRTRASGGYGLGLSIVSRIAFWFNGTMSVDESPKLGGARFTMNWPIKPL
CEEEEHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHH
TQTISADQLTQEKGARKLIDSDS
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]