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The map label for this gene is tesB [H]

Identifier: 148651982

GI number: 148651982

Start: 199482

End: 200375

Strand: Direct

Name: tesB [H]

Synonym: PsycPRwf_0166

Alternate gene names: 148651982

Gene position: 199482-200375 (Clockwise)

Preceding gene: 148651980

Following gene: 148651987

Centisome position: 6.7

GC content: 47.99

Gene sequence:

>894_bases
ATGCCTGATTATAAACAGCTGGTAGATCAACTATTAGATACGGTAAAACTGACCGAGATTTCGGAAAATATCTTTGAAGG
CAAAAGTTATGACTACGTAGGGAAGCGTATCTTTGGCGGTCAAGTACTGGCACAGGCAATAATGGCAGCCGCTCAAACTT
TAGATGAGGATAAGCCTTGTCACTCTTTGCATGGCTATTTTTTGCGTGGCGGCAGTATCGGTCAGCCAGTTATCTATCAG
GTACGACGCTTACGTGATGGGCGCAGTCTGTCAGCGCGTGAAGTAACCGCGGTACAGATGAAACAAGACAATGATGGCAA
TATGATTGAGCAAGTGGTGTTCTCTATGATTGCCTCTTTTTCTCCGATGGAAGGTGGCTTAGACTATCAAGAAGAAATGC
CTGCCTATCCGCCGCCGGAGGATTTAGAGTCTGAGCAGTCGCTAAAAGAGCATCACGTGGGCAGCGTGCCTGAACCGTTA
CGTGAGCGCTTTATGCGTCCGCGTCATGTGGAAATTAAGCCGGTTAAGCCGCGTGATCCCGTATATCCTGAGCCTATGGT
ACCAAGACAGGCCAATTGGCTACGAATTCGTGAGCTTGGCGAACAGCCGGTCGCCATCCAGCAAGCACTGTTGGCGTTCT
CATCAGACTATTATCTGGTAGGCACAGGCCTTATGCCACATGGCATCAGCTTTATGACCAAAGGTTTGCAGGCTGCCAGT
ATTGATCATTCAATGCATTTTCACCGCCCTTTTGATATTAATGAGTGGCTGTTGTATGACATGTGGAGTGACACCACCTC
TCATTCTAAAGGCTTAAACCATGGTCAGTTTTGGCAAAATGGCAATCTGGTAGCGACCGTACAGCAAGAGGGTTTAATGC
GCCTTCGCGGATAG

Upstream 100 bases:

>100_bases
GCTCACTTAAAATAGGCGACCATGTTGTCGATTATTCCAAGGCATCTGGTTTGCTTTAGTAGGCCGGGGTCTTATCAATT
TAGGGTCATTGGAGAGATAA

Downstream 100 bases:

>100_bases
CAATACAAGCTTTTAGATAATCTACTCTGTGTGTCATCATAAAACTGCATTGAAAAAGCCGCTTATCTTAAATCAAGATA
AGCGGCTTTTTTTTGCCCCG

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPDYKQLVDQLLDTVKLTEISENIFEGKSYDYVGKRIFGGQVLAQAIMAAAQTLDEDKPCHSLHGYFLRGGSIGQPVIYQ
VRRLRDGRSLSAREVTAVQMKQDNDGNMIEQVVFSMIASFSPMEGGLDYQEEMPAYPPPEDLESEQSLKEHHVGSVPEPL
RERFMRPRHVEIKPVKPRDPVYPEPMVPRQANWLRIRELGEQPVAIQQALLAFSSDYYLVGTGLMPHGISFMTKGLQAAS
IDHSMHFHRPFDINEWLLYDMWSDTTSHSKGLNHGQFWQNGNLVATVQQEGLMRLRG

Sequences:

>Translated_297_residues
MPDYKQLVDQLLDTVKLTEISENIFEGKSYDYVGKRIFGGQVLAQAIMAAAQTLDEDKPCHSLHGYFLRGGSIGQPVIYQ
VRRLRDGRSLSAREVTAVQMKQDNDGNMIEQVVFSMIASFSPMEGGLDYQEEMPAYPPPEDLESEQSLKEHHVGSVPEPL
RERFMRPRHVEIKPVKPRDPVYPEPMVPRQANWLRIRELGEQPVAIQQALLAFSSDYYLVGTGLMPHGISFMTKGLQAAS
IDHSMHFHRPFDINEWLLYDMWSDTTSHSKGLNHGQFWQNGNLVATVQQEGLMRLRG
>Mature_296_residues
PDYKQLVDQLLDTVKLTEISENIFEGKSYDYVGKRIFGGQVLAQAIMAAAQTLDEDKPCHSLHGYFLRGGSIGQPVIYQV
RRLRDGRSLSAREVTAVQMKQDNDGNMIEQVVFSMIASFSPMEGGLDYQEEMPAYPPPEDLESEQSLKEHHVGSVPEPLR
ERFMRPRHVEIKPVKPRDPVYPEPMVPRQANWLRIRELGEQPVAIQQALLAFSSDYYLVGTGLMPHGISFMTKGLQAASI
DHSMHFHRPFDINEWLLYDMWSDTTSHSKGLNHGQFWQNGNLVATVQQEGLMRLRG

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=304, Percent_Identity=37.5, Blast_Score=177, Evalue=9e-45,
Organism=Escherichia coli, GI1786657, Length=277, Percent_Identity=40.072202166065, Blast_Score=215, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71988741, Length=306, Percent_Identity=29.4117647058824, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115532456, Length=283, Percent_Identity=30.3886925795053, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17531889, Length=283, Percent_Identity=30.3886925795053, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17531885, Length=283, Percent_Identity=30.3886925795053, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI212645202, Length=290, Percent_Identity=30.6896551724138, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17558508, Length=317, Percent_Identity=27.1293375394322, Blast_Score=104, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 33784; Mature: 33653

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDYKQLVDQLLDTVKLTEISENIFEGKSYDYVGKRIFGGQVLAQAIMAAAQTLDEDKPC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HSLHGYFLRGGSIGQPVIYQVRRLRDGRSLSAREVTAVQMKQDNDGNMIEQVVFSMIASF
HHHCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCC
SPMEGGLDYQEEMPAYPPPEDLESEQSLKEHHVGSVPEPLRERFMRPRHVEIKPVKPRDP
CCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEECCCCCC
VYPEPMVPRQANWLRIRELGEQPVAIQQALLAFSSDYYLVGTGLMPHGISFMTKGLQAAS
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCHHHC
IDHSMHFHRPFDINEWLLYDMWSDTTSHSKGLNHGQFWQNGNLVATVQQEGLMRLRG
CCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCCHHHCCC
>Mature Secondary Structure 
PDYKQLVDQLLDTVKLTEISENIFEGKSYDYVGKRIFGGQVLAQAIMAAAQTLDEDKPC
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HSLHGYFLRGGSIGQPVIYQVRRLRDGRSLSAREVTAVQMKQDNDGNMIEQVVFSMIASF
HHHCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCC
SPMEGGLDYQEEMPAYPPPEDLESEQSLKEHHVGSVPEPLRERFMRPRHVEIKPVKPRDP
CCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEECCCCCC
VYPEPMVPRQANWLRIRELGEQPVAIQQALLAFSSDYYLVGTGLMPHGISFMTKGLQAAS
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCHHHC
IDHSMHFHRPFDINEWLLYDMWSDTTSHSKGLNHGQFWQNGNLVATVQQEGLMRLRG
CCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]