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The map label for this gene is mraY

Identifier: 148651954

GI number: 148651954

Start: 165724

End: 166845

Strand: Direct

Name: mraY

Synonym: PsycPRwf_0137

Alternate gene names: 148651954

Gene position: 165724-166845 (Clockwise)

Preceding gene: 148651953

Following gene: 148651955

Centisome position: 5.56

GC content: 46.26

Gene sequence:

>1122_bases
GTGTTATATTGGTTATTTGACAGTTGGTTGAGTCAATTCTATTCACCGTTCTCGGCGGTATCTTCGGTAACCTTGCGTAC
TTTACTCACCGTTATTACCTCGCTTGCTTTTAGCATCATCTTAGGCCCCCGCACCATCGCTTATCTTCGCAGTGTAAAAT
ATGACCAAGCTGTACGTGATGATGGCCCCAAAACCCATTTAGCAAAAACAGGAACGCCCACCATGGGCGGGGTACTGATC
CTAACCTCGATTGGTTTTTCGACCTTATGCTGGGCCAATTTAGCCAATCCCTATGTTTGGATTTTAATGGTGGTCATGGT
TATCTTTGGGGCGGTGGGCTGGGCCGATGACTGGTTAAAAATTAAGTATAAAAACCCCAAAGGCCTAATCGCCCGTAAAA
AGTATTTTTGGCTGTCAGTGGGTGCGTTATTTGTAGGCAGCTCGCTGTATTATATCGCCAGCCAGCAGCCTGACCCTGCT
CAAACCAAAGCCATGGTGGATTTGTTAATTCCCCTATTTAAAAACTGGATAGTGCCTCTATCAGCGCTACCGCTGGGCTT
AGGCTTCATCATCTTTACCTATTTTGTGATTAATGGGTCATCAAATGCCGTCAACTTGACGGATGGCTTAGATGGTCTGG
CCATTTTACCTGTGGTCTTTGTCGCTGCAGGTCTGGGTGTATTTTCTTATGTATCGGGTGATGTGCGCTTCGCTGATTAT
TTGCATGTGCCTTATATCGCTTATAACTCTGAGGTGACCATTGTTTGTGCAGCCATGATTGGCTCAGGCCTTGGTTTTTT
ATGGTACAACGCGCATCCGGCGCAGGTATTTATGGGCGATGTGGGCGCATTGGCACTGGGTGCTATGCTAGGTACCATTG
CCGTTATGACCCGCCAAGAGATAGCCTTTGCCATCATGGGCGGTCTATTTGTTGCGGAAGCTTTATCAGTTATTCTACAG
GTGGGCTCGTTCAAATTACGCAAAAAACGTGTGTTATTAATGGCGCCACTGCACCATCACTTTGAAGAGCTGGGCTGGAA
AGAAACCCAAGTTGTGGTGCGCTTTTGGATTATTGCTATTTTATTGGTAGTGTTAGGACTGATGACCTTAAAGCTGCGTT
AA

Upstream 100 bases:

>100_bases
GATATCGCTTTGGCATAGGCTGCGGCGATGTCATTTTTATTTGTGGTGATTAGGGGCTAAAAACACACATAATTTTTTAA
AAATTTATGAGGAGTAGGCG

Downstream 100 bases:

>100_bases
TACAGCAGGTTAATCAGGGCTACTATTCATCATTTAATCAATAGTTCAAGCAGTAATTTAAGCAATCGTCCCATGTACAG
CAGTTAATAACGGGTGTCAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRDDGPKTHLAKTGTPTMGGVLI
LTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPA
QTKAMVDLLIPLFKNWIVPLSALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADY
LHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVILQ
VGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAILLVVLGLMTLKLR

Sequences:

>Translated_373_residues
MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRDDGPKTHLAKTGTPTMGGVLI
LTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPA
QTKAMVDLLIPLFKNWIVPLSALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADY
LHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVILQ
VGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAILLVVLGLMTLKLR
>Mature_373_residues
MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRDDGPKTHLAKTGTPTMGGVLI
LTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPA
QTKAMVDLLIPLFKNWIVPLSALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADY
LHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVILQ
VGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAILLVVLGLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=373, Percent_Identity=53.0831099195711, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PSYWF (A5WBQ6)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279047.1
- STRING:   A5WBQ6
- GeneID:   5204544
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0137
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   PSP56811:PSYCPRWF_0137-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 41006; Mature: 41006

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11af6020)-; HASH(0x11eec228)-; HASH(0x12846844)-; HASH(0x1281d17c)-; HASH(0x12846748)-; HASH(0x125fab1c)-; HASH(0x121bab44)-; HASH(0x11cd3100)-; HASH(0x1284688c)-; HASH(0x125fabac)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRD
CEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
DGPKTHLAKTGTPTMGGVLILTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLK
CCCCCCCCCCCCCCCCCCHHEEHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
IKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPAQTKAMVDLLIPLFKNWIVPL
EEECCCCCCEEEHHHHHEEHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
SALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADY
HHHHHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHE
LHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQE
EECCEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFAIMGGLFVAEALSVILQVGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECHHHHHHHHCCCHHHHHHHHHHHHHH
LLVVLGLMTLKLR
HHHHHHHHHHCCH
>Mature Secondary Structure
MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRD
CEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
DGPKTHLAKTGTPTMGGVLILTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLK
CCCCCCCCCCCCCCCCCCHHEEHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
IKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPAQTKAMVDLLIPLFKNWIVPL
EEECCCCCCEEEHHHHHEEHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
SALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADY
HHHHHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHE
LHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQE
EECCEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFAIMGGLFVAEALSVILQVGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECHHHHHHHHCCCHHHHHHHHHHHHHH
LLVVLGLMTLKLR
HHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA