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The map label for this gene is degP [H]

Identifier: 148651945

GI number: 148651945

Start: 152506

End: 153930

Strand: Direct

Name: degP [H]

Synonym: PsycPRwf_0128

Alternate gene names: 148651945

Gene position: 152506-153930 (Clockwise)

Preceding gene: 148651943

Following gene: 148651947

Centisome position: 5.12

GC content: 51.02

Gene sequence:

>1425_bases
GTGCTGGCACTGAGTGGCTTTGGCATAGGTAGCTTGGGGCTAACCGCAGGCACAGCTTTATTGGCTACCTCTGCGACTAT
ACCTACGGCAGCACAGGCCGCGGTTGTGGCTTCAGATTTCTCAGATTTGGTGGAGCAGGTGAGCCCGGGCGTTGCTAGAG
TCAACGTAGTGACTAAGGTGAGTGAAGAGGAGCTTGCCAAGGCTCAAACGGTTGAGCTGCTGCGACAGTTCTTCGGCGAC
CGCATTCGCATTCCAGGTGCCCAAACAGCCCCGGCCATTGAATACAACTATGGTACGGGCTTTTTTGTGACCTCAGATGG
TTATCTGTTGACCAATCACCATGTGATTGCGGGGGCAGATAAGATTACGGTCACCTTAAATGACCGCACCGAGCTTGATG
CTACCTTGGTCGGCAGCGATGAGCGCTCTGATGTGGCGGTATTAAAGGTAAAAGCCCAGCCAGGTAAGTCTTATCCTGCG
CTGCCTACCGGTGACTCCAATGCGGTAAAAGTGGGTGAGCCAGTATTGGCTATTGGCTCGCCTTTTGGTTTTGATTATTC
AGCGTCGGCCGGTATCGTCAGTGCCAAGTCGCGTAACTTCTCACGGGATATTAGCGTGCCCTTTATCCAGTCGGATGTGG
CGCTAAACCCAGGCAACTCAGGCGGTCCACTATTTAATCGTAACGGCCAAGTTATTGGCATTAACTCACGAATATTCAGT
GGTACTGGCGGCTATATGGGACTGTCTTTTTCTATCCCCATTAATGAGGCGATGGATATTTATCAGCAGCTAAAACAAAC
CGGTACAGTGTCACGCGCTTATCTGGGTATATTTCCTCAAGACATCGACCGCAACTTGGCCGAAGCTTATGGCCTAAGTA
AGCCGCAAGGGGCGCTACTGATTAAGGTTACCCCTAAATCGCCAGCAGAAGCAGCTGGCCTAAAGGCGGGCGATATCATC
ACCCATTACAACGGCAAAATGATTTTAGAATCCTCTGACCTTTTAAACATCATTAACCGCAGTAAGCCAGGTGAGAGCTT
TAAGGCCGATGTATTGCGTCAAGGCAAAAAGATTGCAGTCATTGGTAAGTTATCAGCAGCGCCCGATGATGTGGCACCAG
ATGCGGTGGTCACTAAGTCTAATAACAGCCAAATTCGTCTAGGCTTGCGCATTCAGGCGCTGCCTCGTGAAAGCTTGGCA
CAGCTGGACGGAGAAGGGGTATTGGTAACCGAGGTAGATCCTACAGGGATAGCAGCCAGAGCTGGTATAAGAGCCGGTGA
CGTTATCACTAACCTGCATCAGAAGTCGATTAAGAGTATCGATGACTTCCAGCGGGCGCTACGTCAATTACCTGAAGCGG
GCGTGGTGACCATTGAGGTGGTGCGTCAAGGTATCCCAGCCATTATCGGTCTGCGTTTGGATTAG

Upstream 100 bases:

>100_bases
CAACAGACCAAAAACGATAGTTAGCGCATTAAAAACAACTTACTTGTCTCAAAGCTTACAAAAAAGCCAAAAAAAGCTTA
AAGCGTTCGGTGCAGGCTCT

Downstream 100 bases:

>100_bases
TTCTGACGCTTATTCGTATTGCCTATTGCAAGAAGGCGATGTCATTTTATAGGGTGGCATCGCTTTTTTTGGGCTATTGA
TGGGGATGGGGCGTTTACCG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLALSGFGIGSLGLTAGTALLATSATIPTAAQAAVVASDFSDLVEQVSPGVARVNVVTKVSEEELAKAQTVELLRQFFGD
RIRIPGAQTAPAIEYNYGTGFFVTSDGYLLTNHHVIAGADKITVTLNDRTELDATLVGSDERSDVAVLKVKAQPGKSYPA
LPTGDSNAVKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRDISVPFIQSDVALNPGNSGGPLFNRNGQVIGINSRIFS
GTGGYMGLSFSIPINEAMDIYQQLKQTGTVSRAYLGIFPQDIDRNLAEAYGLSKPQGALLIKVTPKSPAEAAGLKAGDII
THYNGKMILESSDLLNIINRSKPGESFKADVLRQGKKIAVIGKLSAAPDDVAPDAVVTKSNNSQIRLGLRIQALPRESLA
QLDGEGVLVTEVDPTGIAARAGIRAGDVITNLHQKSIKSIDDFQRALRQLPEAGVVTIEVVRQGIPAIIGLRLD

Sequences:

>Translated_474_residues
MLALSGFGIGSLGLTAGTALLATSATIPTAAQAAVVASDFSDLVEQVSPGVARVNVVTKVSEEELAKAQTVELLRQFFGD
RIRIPGAQTAPAIEYNYGTGFFVTSDGYLLTNHHVIAGADKITVTLNDRTELDATLVGSDERSDVAVLKVKAQPGKSYPA
LPTGDSNAVKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRDISVPFIQSDVALNPGNSGGPLFNRNGQVIGINSRIFS
GTGGYMGLSFSIPINEAMDIYQQLKQTGTVSRAYLGIFPQDIDRNLAEAYGLSKPQGALLIKVTPKSPAEAAGLKAGDII
THYNGKMILESSDLLNIINRSKPGESFKADVLRQGKKIAVIGKLSAAPDDVAPDAVVTKSNNSQIRLGLRIQALPRESLA
QLDGEGVLVTEVDPTGIAARAGIRAGDVITNLHQKSIKSIDDFQRALRQLPEAGVVTIEVVRQGIPAIIGLRLD
>Mature_474_residues
MLALSGFGIGSLGLTAGTALLATSATIPTAAQAAVVASDFSDLVEQVSPGVARVNVVTKVSEEELAKAQTVELLRQFFGD
RIRIPGAQTAPAIEYNYGTGFFVTSDGYLLTNHHVIAGADKITVTLNDRTELDATLVGSDERSDVAVLKVKAQPGKSYPA
LPTGDSNAVKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRDISVPFIQSDVALNPGNSGGPLFNRNGQVIGINSRIFS
GTGGYMGLSFSIPINEAMDIYQQLKQTGTVSRAYLGIFPQDIDRNLAEAYGLSKPQGALLIKVTPKSPAEAAGLKAGDII
THYNGKMILESSDLLNIINRSKPGESFKADVLRQGKKIAVIGKLSAAPDDVAPDAVVTKSNNSQIRLGLRIQALPRESLA
QLDGEGVLVTEVDPTGIAARAGIRAGDVITNLHQKSIKSIDDFQRALRQLPEAGVVTIEVVRQGIPAIIGLRLD

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=351, Percent_Identity=30.7692307692308, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI22129776, Length=313, Percent_Identity=30.0319488817891, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24308541, Length=271, Percent_Identity=32.4723247232472, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI7019477, Length=335, Percent_Identity=28.3582089552239, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789629, Length=460, Percent_Identity=33.695652173913, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786356, Length=464, Percent_Identity=32.1120689655172, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789630, Length=267, Percent_Identity=33.7078651685393, Blast_Score=145, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24646839, Length=264, Percent_Identity=32.1969696969697, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49816; Mature: 49816

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALSGFGIGSLGLTAGTALLATSATIPTAAQAAVVASDFSDLVEQVSPGVARVNVVTKV
CEEEECCCCCCHHHHHCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC
SEEELAKAQTVELLRQFFGDRIRIPGAQTAPAIEYNYGTGFFVTSDGYLLTNHHVIAGAD
CHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCEEEEECCCEEEECCEEEECCC
KITVTLNDRTELDATLVGSDERSDVAVLKVKAQPGKSYPALPTGDSNAVKVGEPVLAIGS
EEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEECC
PFGFDYSASAGIVSAKSRNFSRDISVPFIQSDVALNPGNSGGPLFNRNGQVIGINSRIFS
CCCCCCCCCCCEEEECCCCCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEECCEEEE
GTGGYMGLSFSIPINEAMDIYQQLKQTGTVSRAYLGIFPQDIDRNLAEAYGLSKPQGALL
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEE
IKVTPKSPAEAAGLKAGDIITHYNGKMILESSDLLNIINRSKPGESFKADVLRQGKKIAV
EEECCCCCHHHCCCCCCCEEEEECCEEEEECHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
IGKLSAAPDDVAPDAVVTKSNNSQIRLGLRIQALPRESLAQLDGEGVLVTEVDPTGIAAR
EEECCCCCCCCCCCEEEECCCCCEEEEEEEEEECCHHHHHHCCCCEEEEEECCCCCCHHH
AGIRAGDVITNLHQKSIKSIDDFQRALRQLPEAGVVTIEVVRQGIPAIIGLRLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCEEEEEEEC
>Mature Secondary Structure
MLALSGFGIGSLGLTAGTALLATSATIPTAAQAAVVASDFSDLVEQVSPGVARVNVVTKV
CEEEECCCCCCHHHHHCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC
SEEELAKAQTVELLRQFFGDRIRIPGAQTAPAIEYNYGTGFFVTSDGYLLTNHHVIAGAD
CHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCEEEEECCCEEEECCEEEECCC
KITVTLNDRTELDATLVGSDERSDVAVLKVKAQPGKSYPALPTGDSNAVKVGEPVLAIGS
EEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEECC
PFGFDYSASAGIVSAKSRNFSRDISVPFIQSDVALNPGNSGGPLFNRNGQVIGINSRIFS
CCCCCCCCCCCEEEECCCCCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEECCEEEE
GTGGYMGLSFSIPINEAMDIYQQLKQTGTVSRAYLGIFPQDIDRNLAEAYGLSKPQGALL
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEE
IKVTPKSPAEAAGLKAGDIITHYNGKMILESSDLLNIINRSKPGESFKADVLRQGKKIAV
EEECCCCCHHHCCCCCCCEEEEECCEEEEECHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
IGKLSAAPDDVAPDAVVTKSNNSQIRLGLRIQALPRESLAQLDGEGVLVTEVDPTGIAAR
EEECCCCCCCCCCCEEEECCCCCEEEEEEEEEECCHHHHHHCCCCEEEEEECCCCCCHHH
AGIRAGDVITNLHQKSIKSIDDFQRALRQLPEAGVVTIEVVRQGIPAIIGLRLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]